Containment Gene Therapy In-Vitro In-Vivo 
Pharmaceutical Technology
MAY 12, 2023
The in vivo study, conducted in mice, involved a phosphatidylserine-containing nano-formulation of mRNA supplied by BioNTech, distinct from traditional lipid nanocrystals (LNCs). Whilst the formulation had been successful in vitro , the oral administration in mice did not elicit activity.
Drug Discovery World
OCTOBER 27, 2023
With cues from a diverse population of tissue-specific cell types, extracellular matrix proteins, and biomechanical forces, cells grown in organ-chips closely emulate their in vivo counterparts and replicate tissue-level functions. But can organ-chips entirely replace other models? Not yet, according to Ewart.
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