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The importance of glycan analysis and characterisation for biopharma

Drug Discovery World

This initial work, which was published in Analytical Biochemistry and co-authored by scientists from both NIBRT and Agilent (Xie et al, 2021), includes the analysis of glycan profiles of two mAbs, human polyclonal antibodies and the total protein in human serum. The glycan database . This complexity makes quantification challenging. .

Protein 52
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The evolution of assays for immuno-oncology research

Drug Discovery World

Cancer is a complex heterogenous multistep disease characterised by uncontrolled cell proliferation combined with a dysregulated immune response. A healthy immune system is naturally primed to eliminate malignant and abnormal cells through a synchronised and dynamic interplay between adaptive and innate immunity.