Grand Rounds May 19, 2023: Aspirin or Low-Molecular-Weight Heparin for Thromboprophylaxis After a Fracture (Robert O’Toole, MD)
Rethinking Clinical Trials
MAY 25, 2023
The North American guideline is to give Low Molecular Weight Heparin (LMWH) in cases of orthopedic trauma for VTE prophylaxis. Aspirin vs. Low Molecular Weight Heparin for Thromboprophylaxis: A Randomized Clinical Trial of Over 12,000 Orthopedic Trauma Patients (PREVENT CLOT) was conducted through METRC at 21 centers across the country.
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