pharmaphorum

NOVEMBER 28, 2022

Tralokinumab is a high-affinity human monoclonal antibody that specifically targets and neutralises interleukin (IL)-13 cytokine, which plays an important role in the immune and inflammatory processes underlying AD signs and symptoms.

Dermatology 52

Dermatology Trials Medicine Antibody 52

The Pharma Data

MARCH 28, 2022

Dupixent peak sales ambition raised to more than €13 billion Chronic obstructive pulmonary disease 2023 pivotal readouts provide potential for additional Dupixent sales ambition upgrade 13 potential new medicines currently in the clinic to treat chronic inflammatory diseases, with 17 readouts expected by the end of 2024.

Medicine 52

Medicine Sales Clinical Development Development 52

pharmaphorum

JUNE 2, 2021

The deal gives Amgen rights to the KHK4083 antibody in all countries except Kyowa’s home market of Japan, and is back-loaded with potential milestone payments worth another $850 million plus royalties on sales. Kyowa will co-promote the drug in the US if approved, with opt-in rights in some other countries as well.

Drugs 52

Drugs Licensing Licensing Sales 52

The Pharma Data

AUGUST 3, 2021

Product sales increased 3% globally, driven by double digit volume growth across a number of our products including Prolia ® (denosumab), Repatha ® (evolocumab) and our biosimilar products MVASI ® (bevacizumab-awwb) and KANJINTI ® (trastuzumab-anns). Product Sales Performance. Key results include: Total revenues increased 5% to $6.5

Sales 52

Sales Production Antibody Development 52

pharmaphorum

APRIL 26, 2021

The drug is a nanobody, a molecule around one-tenth the size of a regular antibody derived from camelid species such as the llama. Proponents say they can offer greater stability, smaller size, higher potency, and lower production or synthesis costs compared to conventional monoclonal antibodies. billion in sales last year.

Antibody 52

Antibody Drugs Marketing Licensing 52

pharmaphorum

AUGUST 16, 2021

billion to take control of lebrikizumab’s developer Dermira last year after the antibody showed promising results in phase 2b trials, and has been waiting for the results of the phase 3 trials to see if that was a good move. Lilly shelled out $1.1

Antibody 52

Antibody Trials Marketing Drugs 52

pharmaphorum

SEPTEMBER 29, 2022

The disorder – driven by type 2 inflammation characterised by an antibody-based immune response – causes hard lumps or nodules to form on the skin that are so itchy they can lead patients to scratch themselves to the point of bleeding or pain.

Drugs 69

Drugs Immune Response Allergies Sales 69

pharmaphorum

JANUARY 6, 2023

It is estimated to be a market opportunity worth over $4 billion. The estimated market opportunity value for that is in excess of $2.5 As Dr Shao-Lee Lin, founder and CEO of ACELYRIN, commented: “The acquisition of ValenzaBio adds additional programmes to our portfolio, such as lonigutamab.”.

Trials 59

Trials Marketing Protein Antibody 59

pharmaphorum

MAY 25, 2022

But while the company is adamant sales will pick up quickly, analysts have predicted a more challenging start for the new product. Dermavant has said it is planning a swift rollout for Vtama, with the commercial team in place for a launch early next month.

Drugs 52

Drugs FDA Approval Licensing Licensing 52

pharmaphorum

AUGUST 2, 2021

UCB’s bimekizumab hasn’t been approved for marketing in Europe yet, but has already been given the nod for NHS use in England and Wales under a new fast-track scheme introduced by NICE.

Marketing 52

Marketing Medicine Production Sales 52

The Pharma Data

NOVEMBER 8, 2020

9, 2020 /PRNewswire/ — Solid 9M business performance despite COVID-19 and generic Aczone challenges: Net Sales €613.8 Ilumetri ® sales grew +125% year-on-year and Seysara ® showed Net Sales performance improvement quarter-on-quarter following clinically relevant FDA label improvement. BARCELONA, Spain , Nov.

Dermatology 52

Dermatology Sales Marketing Production 52

The Pharma Data

AUGUST 19, 2020

The transaction will include full global rights to nipocalimab (M281), a clinically validated, potentially best-in-class anti-FcRn antibody. Janssen expects nipocalimab to contribute to its goals of achieving above-market growth over the mid and long term. Nipocalimab recently received a rare pediatric disease designation from the U.S.

Production 52

Production Dermatology Development Containment 52

The Pharma Data

AUGUST 19, 2020

The transaction will include full global rights to nipocalimab (M281), a clinically validated, potentially best-in-class anti-FcRn antibody. Janssen expects nipocalimab to contribute to its goals of achieving above-market growth over the mid and long term. Nipocalimab recently received a rare pediatric disease designation from the U.S.

Production 40

Production Dermatology Development Containment 40

The Pharma Data

SEPTEMBER 15, 2020

On a non-risk adjusted basis, these opportunities collectively represent more than $15 billion (excluding 20vPnC) in potential incremental revenue for Pfizer from 2020 to 2025, as well as aggregate peak annual sales potential of $35 billion to $40 billion (including 20vPnC). for RSV A and 18.0 Inflammation and Immunology.

Gene Therapy 52

Gene Therapy Vaccination Vaccine Trials 52