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Turning science into business: An optimised alternative to antibodies

Drug Discovery World

DS: What motivated you and Dr David Bunka, CTO, to create Aptamer and did you imagine you would one day be operating on such a global scale?    I quickly recognised the commercial value of aptamers as being able to address the gap in the market where antibodies fail to perform, and together we established the business to begin aptamer development.

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Reflecting on ELRIG’s Drug Discovery 2022 

Drug Discovery World

The DDW team spent 4-5 October, 2022 at ELRIG’s annual meeting, Drug Discovery 2022, which remains Europe’s largest meeting for life sciences industry professionals and took place at ExCel, London, UK. Drug Discovery 2022: The numbers . Drug Discovery 2022: The numbers . Of those delegates, 75% work in drug discovery.

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Receptor Occupancy Assays by Flow Cytometry: Benefits for Clinical Trials

XTalks

Both the areas of drug development and clinical trials are increasingly using in vitro assays to help determine the efficacy of an investigational therapeutic. All drug development processes evaluate a drug’s pharmacokinetics (PK) to gather data about its absorption, distribution, metabolism, and excretion in the body.

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The evolution of assays for immuno-oncology research

Drug Discovery World

Evolution of such defence mechanisms can lead to multi-drug resistance, further disease progression, and cancer metastasis. Cancer is a complex heterogenous multistep disease characterised by uncontrolled cell proliferation combined with a dysregulated immune response. This continues to be the standard of care.

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Highlights from SLAS2023: Day One

Drug Discovery World

The company launched its EnVision Nexus system at the show, which is designed for demanding HTS applications and to help accelerate drug discovery efforts. As the company’s first HT system, it has been designed to overcome adoption barriers currently limiting the use of predictive human liver models within drug discovery workflows.

Drugs 52