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New method identifies antibody-like proteins with diagnostic and therapeutic potential for SARS-CoV-2

Scienmag

Antibody-like proteins that capture and neutralize SARS-CoV-2 Scientists have used a new high-speed, in vitro selection method to isolate 9 antibody-like proteins (ALPs) that bind to the SARS-CoV-2 virus – 4 of which also exhibited neutralizing activity – within 4 days, according to a new study.

Protein 53
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A protein-based COVID-19 vaccine that mimics the shape of the virus

The Pharma Data

Even as several safe and effective COVID-19 vaccines are being administered to people worldwide, scientists are still hard at work developing different vaccine strategies that could provide even stronger or longer-lasting immunity against SARS-CoV-2 and its variants.

Protein 52
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What to expect from PEGS Europe 2023: Day 1

Drug Discovery World

Ahead of protein and antibody engineering conference PEGS Europe 2024 in Lisbon, DDW’s Megan Thomas looks at what to expect from each track of the annual biologics technology meeting.

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How T Cell Tests Could Trump Antibody Tests in the Detection of COVID-19

XTalks

A new type of test based on detection of activated T cells may prove to have greater utility in determining whether someone has had a COVID-19 infection compared to a traditional antibody test. Researchers at Adaptive Biotechnologies compared T-Detect to a commercial antibody test from DiaSorin on samples obtained from people in Vo’, Italy.

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Reflections on the 1-Year Anniversary of the COVID-19 Pandemic

XTalks

Amidst initial confusion, fear and chaos, masks and social distancing quickly became new norms, and now vaccines are leading hope for a way out. As a novel virus, public health experts, scientists and clinicians faced challenges in how to effectively prevent its transmission, and how to best treat it in the most severe cases.

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DDW Turning Science into Business Summit: Cancer research

Drug Discovery World

Seiler echoed these sentiments, particularly the evolution of cancer therapeutics in which we aim to target the cancer itself, and the turning point of about ten years ago where scientists began engaging the immune system for controlling homeostasis within individual tissues and organs.

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The evolution of assays for immuno-oncology research

Drug Discovery World

These have been the most promising form of antibodies being developed, with Ipilimumab (CTLA4 blocking) and Nivolumab (PD1 blocking) now approved by the US Food and Drug Administration (FDA) for more than nine cancer types. Half of people diagnosed with cancer in England and Wales survive their disease for 10 years or more (2010-11) 1.