Drug Discovery World

SEPTEMBER 26, 2022

The bacteria in the intestinal tract (‘ microbiota’ ) play an important role in the success of ICI therapy, suggesting that crosstalk between the immune system and bacteria in the intestine can impact the overall anti-tumor T-cell activation status. .

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Bacteria Biobanking In-Vivo In-Vitro 52

Drug Discovery World

OCTOBER 13, 2022

These included: HUB Organoids as a preclinical tool for inflammatory bowel disease (IBD) drug development; Autologous organoids and T cell co-cultures in immunotherapy drug development ; Patient-derived organoids to predict clinical response ; Hub Organoid-bacteria co-culture system in assessing host-pathogen interaction s; and Developing a patient-derived (..)

Drugs 52

Drugs In-Vivo In-Vitro Biobanking 52

The Pharma Data

JULY 12, 2021

The last step, called target validation in preclinical models, was conducted in a first-of-its-kind Phase ‘0’ clinical trial using a living biobank of organoids created from IBD patients at?The?HUMANOID HUMANOID Center of Research Excellence?(CoRE), CoRE), the translational arm of iNetMed.

Drugs 52

Drugs Gene Expression Big Data Gene 52

The Pharma Data

JANUARY 21, 2021

Four years ago, the University of Malta established a national ALS Registry and Biobank to identify ALS patients and collect data on their residence, occupation, lifestyle and environmental exposures. Amyotrophic lateral sclerosis (ALS) is a progressive neurological disease that destroys the nerves linked to the muscles.

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Research DNA Hormones Vaccination 52