BioSpace

OCTOBER 20, 2022

Kite Pharma entered into a global licensing deal with Refuge Biotechnologies to leverage the latter's propriety gene expression plaform and develop potential blood cancer therapies.

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Gene Expression Gene Licensing Licensing 78

Scienmag

JULY 22, 2021

Strong social connections and greater maternal care early in life can influence molecular markers related to gene expression in DNA and future stress response, suggests a […]. Holekamp Having friends may not only be good for the health of your social life, but also for your actual health–if you’re a hyena, that is.

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Gene Expression Gene DNA Genetics 97

Scienmag

JANUARY 27, 2022

Researchers at Baylor College of Medicine, Yale University and other institutions have identified previously unrecognized changes in gene expression and cellular interactions in distinct cell populations in chronic obstructive pulmonary disease (COPD).

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Gene Expression Gene Medicine Research 72

Scienmag

NOVEMBER 25, 2021

A team led by researchers at Baylor College of Medicine and the Czech Academy of Sciences has uncovered a new piece of the puzzle of how gene expression is orchestrated. Published in the journal Science, the findings reveal a novel mechanism that coordinates the assembly of components inside cells that control gene expression.

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Gene Expression Gene Protein Medicine 66

Bio Pharma Dive

AUGUST 30, 2023

The China-based company is one of at least four young biotechs in a competitive race to use CRISPR tools to alter gene expression without changing DNA.

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Gene Expression Gene DNA 157

Scienmag

OCTOBER 1, 2020

The type and direction of the force on a cell alters gene expression by stretching different regions of DNA, researchers at University of […]. . — Tissues and cells in the human body are subjected to a constant push and pull – strained by other cells, blood pressure and fluid flow, to name a few.

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Gene Expression Gene DNA Research 70

Bio Pharma Dive

NOVEMBER 17, 2021

Chroma Medicine's launch is the latest step in a decadeslong quest by drugmakers to capitalize on research into epigenetics, a way of controlling gene expression without altering DNA.

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Gene Expression Gene DNA Medicine 322

Scienmag

MARCH 9, 2021

CHOP researchers find small changes in RNA due to RNA editing could have a large impact on gene expression and phenotype Philadelphia, March 9, 2021–Combining computational mining of big data with experimental testing in the lab, researchers at Children’s Hospital of Philadelphia (CHOP) have identified RNA editing events that influence (..)

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Gene Expression RNA Gene Research 53

Scienmag

MARCH 11, 2021

Study marks the first time this complex has been visualized for human cells Credit: Northwestern University For the first time ever, a Northwestern University-led research team has peered inside a human cell to view a multi-subunit machine responsible for regulating gene expression.

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Gene Expression Gene Research Regulation 51

Scienmag

DECEMBER 1, 2021

BOSTON – An important player in the healthy development of female embryos turns out also to play a key role in regulating the behavior of chromosome loops and gene expression in both sexes, according to a new study by researchers at Massachusetts General Hospital (MGH).

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Gene Expression Gene RNA Research 61

AuroBlog - Aurous Healthcare Clinical Trials blog

DECEMBER 15, 2022

“We observed that gene expression in the brain tissue of patients who died […]. Severe COVID-19 looks scarily like old age in the human brain, according to a postmortem analysis of 54 healthy and infected individuals.

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Gene Expression Gene Research Clinical Trials 215

Scienmag

DECEMBER 21, 2020

LJI scientists track down control elements that govern gene expression from a distance Credit: Alex Fung LA JOLLA–The COVID-19 pandemic has highlighted how our small genetic differences can have a tremendous effect on how our bodies respond to disease. “The difference is within us,” says Vivek Chandra, Ph.D.,

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Gene Expression Gene Genetics Scientist 52

BioTech 365

APRIL 20, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Algorithm maps gene expression in space.As we accumulate more and more gene-sequencing information, cell-type databases are growing in both size and complexity.

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Gene Expression Gene Gene Sequencing Research 40

BioTech 365

OCTOBER 14, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Protein that manipulates gene expression inside the cell nucleus could inspire new RSV drugs, vaccines.Protein that manipulates gene expression inside the cell nucleus could inspire new RSV … Continue reading →

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Gene Expression Gene Protein Drugs 40

BioTech 365

JUNE 28, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: ADA: TB vaccine repurposed in Type 1 diabetes restores gene expression in key immune cells.ADA: TB vaccine repurposed in Type 1 diabetes restores gene expression in key … Continue reading →

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Gene Expression Gene Vaccination Vaccine 40

BioTech 365

APRIL 1, 2021

10x Genomics Puts Single Cell Analysis Within Reach of All With Low Throughput Gene Expression Kit 10x Genomics Puts Single Cell Analysis Within Reach of All With Low Throughput Gene Expression Kit Along with recent release of CellPlex, product increases … Continue reading →

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Gene Expression Genome Genomics Gene 40

BioTech 365

DECEMBER 1, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Researchers identify key RNA “gatekeeper” in gene expression, pointing to possible new drug targets.An

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Gene Expression RNA Gene Drugs 40

BioTech 365

APRIL 9, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: MIT and UCSF researchers create CRISPR ‘on-off switch’ that controls gene expression without changing DNA.MIT and UCSF researchers create CRISPR ‘on-off switch’ that controls gene expression without … Continue reading → (..)

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Gene Expression Gene Research DNA 40

BioTech 365

JUNE 2, 2021

Resolve Biosciences Launches Commercial Molecular Cartography™ Services to Provide Scientists with Highest-Resolution View of Subcellular Gene Expression Resolve Biosciences Launches Commercial Molecular Cartography™ Services to Provide Scientists with Highest-Resolution View of Subcellular Gene Expression Company expands global footprint (..)

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Gene Expression Gene Scientist 40

Scienmag

JUNE 24, 2022

BIRMINGHAM, Ala. While lower vertebrates can repair their adult hearts after a heart attack, mammals — including humans — cannot. The ability to regenerate dead muscle tissue in mammalian hearts disappears just a few days after birth because the heart muscle cells, called cardiomyocytes, exit the cell cycle. Credit: UAB BIRMINGHAM, Ala.

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Gene Expression Gene 76

BioTech 365

JULY 28, 2021

BostonGene Announces Publication in Clinical Cancer Research Identifying the Cellular Features and Gene Expression Characteristics Underlying MRI Visibility in Prostate Cancer BostonGene Announces Publication in Clinical Cancer Research Identifying the Cellular Features and Gene Expression Characteristics Underlying MRI Visibility in … Continue (..)

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Gene Expression Gene Research 52

Medical Xpress

MARCH 8, 2023

Scientific evidence shows how the cognitive decline in Alzheimer's disease (AD) is caused by the buildup of amyloid beta proteins, which promote synaptic malfunction.

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Gene Expression Gene Scientist Protein 84

BioTech 365

SEPTEMBER 20, 2021

Global Gene Expression Market Size, Share & Trends Analysis 2021-2028 by Product (DNA Chip/Microarray, Kits & Reagents), Technique (Promoter Analysis, RNA Exp.) – ResearchAndMarkets.com Global Gene Expression Market Size, Share & Trends Analysis 2021-2028 by Product (DNA Chip/Microarray, Kits & … Continue reading → (..)

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Gene Expression Reagent RNA DNA 40

Pharmaceutical Technology

JULY 29, 2022

Ultragenyx uses adeno-associated virus 8 (AAV8) gene therapy to induce stable OTC gene expression. This treatment activates the OTC gene so that ammonia can be removed from the blood. In CAMP4’s approach, regRNAs are drugged with antisense oligonucleotides to control the direction of gene expression.

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RNA Gene Expression Gene Therapy Gene 245

BioTech 365

APRIL 9, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: New, reversible CRISPR method can control gene expression while leaving underlying DNA sequence unchanged.Over the past decade, the CRISPR-Cas9 gene editing system has revolutionized genetic engineering, allowing … Continue (..)

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Gene Expression Gene DNA Gene Editing 40

Pharmaceutical Technology

JANUARY 19, 2023

AOC 1020 has been designed for the treatment of the underlying cause of FSHD, which is caused by the abnormal expression of a gene known as double homeobox 4 or DUX4. Avidity Biosciences’ AOC 1020 is intended to reduce the DUX4 mRNA and DUX4 protein expression in muscles in these patients.

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Gene Expression Gene Clinical Trials Clinical Trials 246

Medical Xpress

MARCH 25, 2023

A new study examining the gene expression of gut microbes suggests that the heart-healthy benefits of walnuts may be linked to beneficial changes in the mix of microbes found in our gut. The findings could help identify other foods or supplements with similar nutritional benefits.

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Gene Expression Gene Cardiology 127

Pharmaceutical Technology

NOVEMBER 28, 2022

A key natural regulator, NRF2 controls antioxidant genes’ expression. The company’s lead molecules in the oral NRF2 Activator programme have been demonstrated to substantially activate NRF2 on dosing orally, offering anti-inflammatory and antioxidant activity.

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Gene Expression Development Clinical Trials Clinical Trials 264

BioTech 365

JANUARY 31, 2022

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: A new method for mapping gene expression deep in the body could one day be used to track stem cells or cancer therapy.Even fans of black-and-white film … Continue reading →

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Gene Expression Gene Research 40

BioTech 365

DECEMBER 8, 2020

Rocket Pharmaceuticals Announces Positive Gene Expression, Clinical Biomarker and Preliminary Functional Data from Phase 1 Trial of RP-A501 for the Treatment of Danon Disease Rocket Pharmaceuticals Announces Positive Gene Expression, Clinical Biomarker and Preliminary Functional Data from Phase 1 Trial … Continue reading →

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Gene Expression Gene Trials 40

Drug Discovery Today

MAY 14, 2020

Users will be able to analyse either fresh/fixed frozen or FFPE samples and rapidly create single cell gene expression maps of up to 600 genes.

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Gene Expression Gene Reagent 40

Scienmag

SEPTEMBER 30, 2021

Crop legumes are an integral part of sustainable agriculture, as several of these species represent an important protein source for both human and animal populations. Legumes engage in a unique and beneficial interaction with a group of soil bacteria, collectively called rhizobia.

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Gene Expression Gene Bacteria Protein 80

Scienmag

JULY 12, 2021

The function of a protein can depend on its abundance in a cell. So, when investigating the properties of a new protein, it is essential to make sure that the same amount is produced by every cell. Researchers at Baylor College of Medicine and Rice University have found a new way to do just that […].

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Gene Expression Gene Protein Engineer 63

Medical Xpress

NOVEMBER 8, 2022

A gene expression-based screening assay using chimeric mice with humanized hepatocytes revealed that letrozole has a modifying effect on fibrosis-related gene expression in the hepatocytes, including YAP, CTGF, TGF-?, and CYP26A1.

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Gene Expression Gene 75

Scienmag

JULY 6, 2022

A University of Minnesota Twin Cities-led team has developed a new technique that allows scientists and engineers to, for the first time, visualize mRNA molecules in the brains of living mice.

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Gene Expression Research Gene Scientist 90

Medical Xpress

DECEMBER 13, 2022

If humans are ever going to be able to regrow damaged tissues the way lizards and fish routinely do, it will require the precise control of gene expression in time and place—otherwise you might end up with random cells growing everywhere or a new body part that never quits growing.

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Gene Gene Therapy Gene Expression Research 98

Medical Xpress

NOVEMBER 24, 2022

But they are also involved in regulating the genes expressed within—and the signaling between—cells. When we consume fats (also called lipids) in our diet, they can be metabolized or stored to provide energy for the body.

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Immune Response Gene Expression Gene Research 98