Study highlights role of disordered protein interactions in gene expression

Scienmag

A team led by researchers at Baylor College of Medicine and the Czech Academy of Sciences has uncovered a new piece of the puzzle of how gene expression is orchestrated. Published in the journal Science, the findings reveal a novel mechanism that coordinates the assembly of components inside cells that control gene expression. Latest News Disordered expression gene highlights interactions protein role study

Early-life social connections influence gene expression, stress resilience

Scienmag

Strong social connections and greater maternal care early in life can influence molecular markers related to gene expression in DNA and future stress response, suggests a […]. Credit: Kay E.

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Researchers speed identification of DNA regions that regulate gene expression

Scienmag

Jude Children’s Research Hospital scientists have developed a highly efficient method to address a major challenge in biology–identifying the genetic ‘switches’ that regulate gene expression. Biology Gene Therapy Genes Genetics Medicine/Health

Researchers reveal 3D structure responsible for gene expression

Scienmag

Study marks the first time this complex has been visualized for human cells Credit: Northwestern University For the first time ever, a Northwestern University-led research team has peered inside a human cell to view a multi-subunit machine responsible for regulating gene expression.

Gene expression altered by direction of forces acting on cell

Scienmag

The type and direction of the force on a cell alters gene expression by stretching different regions of DNA, researchers at University of […]. CHAMPAIGN, Ill. — Tissues and cells in the human body are subjected to a constant push and pull – strained by other cells, blood pressure and fluid flow, to name a few.

The Equalizer: An engineered circuit for uniform gene expression

Scienmag

The function of a protein can depend on its abundance in a cell. So, when investigating the properties of a new protein, it is essential to make sure that the same amount is produced by every cell. Researchers at Baylor College of Medicine and Rice University have found a new way to do just that […]. Technology and Engineering Biology Biomedical/Environmental/Chemical Engineering Biotechnology Cell Biology Genetics

Salt stress alters legume responses to symbiotic rhizobacteria by modulating gene expression

Scienmag

Social & Behavioral Science alters expression gene legume modulating responses rhizobacteria salt stress symbioticCrop legumes are an integral part of sustainable agriculture, as several of these species represent an important protein source for both human and animal populations.

#news #biotech Algorithm maps gene expression in space

BioTech 365

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Algorithm maps gene expression in space.As we accumulate more and more gene-sequencing information, cell-type databases are growing in both size and complexity. There is a need to … Continue reading → #news

#news #biotech Protein that manipulates gene expression inside the cell nucleus could inspire new RSV drugs, vaccines

BioTech 365

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Protein that manipulates gene expression inside the cell nucleus could inspire new RSV drugs, vaccines.Protein that manipulates gene expression inside the cell nucleus could inspire new RSV … Continue reading → #news

#news #biotech Study highlights role of disordered protein interactions in gene expression

BioTech 365

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Study highlights role of disordered protein interactions in gene expression.A team led by researchers at Baylor College of Medicine and the Czech Academy of Sciences has uncovered … Continue reading → #news

Quantitative approach on understanding how epigenetic switches control gene expression

Scienmag

Biology GenesCredit: Nucleic Acids Research Scientists at Tokyo Institute of Technology decipher how to quantitatively assess the effects of specific epigenetic changes on the rate of transcription by developing a mathematical model.

BostonGene Announces Publication in Clinical Cancer Research Identifying the Cellular Features and Gene Expression Characteristics Underlying MRI Visibility in Prostate Cancer

BioTech 365

10x Genomics Puts Single Cell Analysis Within Reach of All With Low Throughput Gene Expression Kit

BioTech 365

10x Genomics Puts Single Cell Analysis Within Reach of All With Low Throughput Gene Expression Kit 10x Genomics Puts Single Cell Analysis Within Reach of All With Low Throughput Gene Expression Kit Along with recent release of CellPlex, product increases … Continue reading → GlobeNewswire

New 3D maps reveal inner workings of immune cell gene expression

Scienmag

LJI scientists track down control elements that govern gene expression from a distance Credit: Alex Fung LA JOLLA–The COVID-19 pandemic has highlighted how our small genetic differences can have a tremendous effect on how our bodies respond to disease.

#news #biotech ADA: TB vaccine repurposed in Type 1 diabetes restores gene expression in key immune cells

BioTech 365

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: ADA: TB vaccine repurposed in Type 1 diabetes restores gene expression in key immune cells.ADA: TB vaccine repurposed in Type 1 diabetes restores gene expression in key … Continue reading → #news

Global Gene Expression Market Size, Share & Trends Analysis 2021-2028 by Product (DNA Chip/Microarray, Kits & Reagents), Technique (Promoter Analysis, RNA Exp.) – ResearchAndMarkets.com

BioTech 365

Global Gene Expression Market Size, Share & Trends Analysis 2021-2028 by Product (DNA Chip/Microarray, Kits & Reagents), Technique (Promoter Analysis, RNA Exp.) – ResearchAndMarkets.com Global Gene Expression Market Size, Share & Trends Analysis 2021-2028 by Product (DNA Chip/Microarray, Kits & … Continue reading → Business Wire

Resolve Biosciences Launches Commercial Molecular Cartography™ Services to Provide Scientists with Highest-Resolution View of Subcellular Gene Expression

BioTech 365

Resolve Biosciences Launches Commercial Molecular Cartography™ Services to Provide Scientists with Highest-Resolution View of Subcellular Gene Expression Resolve Biosciences Launches Commercial Molecular Cartography™ Services to Provide Scientists with Highest-Resolution View of Subcellular Gene Expression Company expands global footprint with opening … Continue reading → Business Wire

Study reports novel role of enzyme in plant immunity and defense gene expression

Scienmag

A recently published article in the Molecular Plant-Microbe Interactions journal provides new evidence that pathogens are hijacking the plant immune system to cause disease while providing insights into a newly discovered mechanism. A large variety of pathogens infect plants and cause different diseases, which can lead to reduced crop yields. During infection, pathogens secrete effector […].

#news #biotech New, reversible CRISPR method can control gene expression while leaving underlying DNA sequence unchanged

BioTech 365

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: New, reversible CRISPR method can control gene expression while leaving underlying DNA sequence unchanged.Over the past decade, the CRISPR-Cas9 gene editing system has revolutionized genetic engineering, allowing … Continue reading → #news

#news #biotech MIT and UCSF researchers create CRISPR ‘on-off switch’ that controls gene expression without changing DNA

BioTech 365

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: MIT and UCSF researchers create CRISPR ‘on-off switch’ that controls gene expression without changing DNA.MIT and UCSF researchers create CRISPR ‘on-off switch’ that controls gene expression without … Continue reading → #news

#news #biotech Understudied mutations have big impact on gene expression

BioTech 365

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Understudied mutations have big impact on gene expression.An international team of researchers led by computer scientists at the University of California San Diego have identified 163 variable … Continue reading → #news

Key early steps in gene expression captured in real time by CSU researchers

Scienmag

Capturing how RNA polymerase enzymes kick off transcription On scales too small for our eyes to see, the business of life happens through the making of proteins, which impart to our cells both structure and function. Cellular proteins get their marching orders from genetic instructions encoded in DNA, whose sequences are first copied and made […]. Chemistry AND Physics Biochemistry Bioinformatics Biology Biomechanics/Biophysics Genetics

#news #biotech How epigenetic switches control gene expression

BioTech 365

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: How epigenetic switches control gene expression.Scientists at Tokyo Institute of Technology have deciphered how to quantitatively assess the effects of specific epigenetic changes on the rate of … Continue reading → #news

A startup emerges with $125M and plans to edit the epigenome

Bio Pharma Dive

Chroma Medicine's launch is the latest step in a decadeslong quest by drugmakers to capitalize on research into epigenetics, a way of controlling gene expression without altering DNA

For the first time, researchers describe how Rho protein really stops gene expression

BioTech 365

Source : Biology Textbooks Wrong?

Rocket Pharmaceuticals Announces Positive Gene Expression, Clinical Biomarker and Preliminary Functional Data from Phase 1 Trial of RP-A501 for the Treatment of Danon Disease

BioTech 365

Rocket Pharmaceuticals Announces Positive Gene Expression, Clinical Biomarker and Preliminary Functional Data from Phase 1 Trial of RP-A501 for the Treatment of Danon Disease Rocket Pharmaceuticals Announces Positive Gene Expression, Clinical Biomarker and Preliminary Functional Data from Phase 1 Trial … Continue reading → Business Wire

Racial/ethnic variation found in nasal gene expression of key protein used by SARS-CoV-2

Scienmag

Findings suggest one factor that may contribute to disparities in COVID-19 infection New York – In a study published in JAMA today, Mount Sinai researchers report findings that shed some light on the disproportionate impact of COVID-19 on Blacks, who have experienced rates of infection and death that are much greater, in some areas twice […]. Medicine & Health Biology Genetics Medicine/Health

#news #biotech The plant hormone auxin may promote disease by regulating virulence gene expression

BioTech 365

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: The plant hormone auxin may promote disease by regulating virulence gene expression.Scientists have long known that the plant hormone auxin controls many aspects of plant growth, development, … Continue reading → #news

#news #biotech GTEx Consortium releases fresh insights into how DNA differences govern gene expression

BioTech 365

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: GTEx Consortium releases fresh insights into how DNA differences govern gene expression.Scientists from the Genotype-Tissue Expression (GTEx) project, a National Institutes of Health-funded consortium including researchers from … Continue reading → #news

CARTANA launches expanded range of In Situ Sequencing kits for high throughput single cell gene expression mapping

Drug Discovery Today

Users will be able to analyse either fresh/fixed frozen or FFPE samples and rapidly create single cell gene expression maps of up to 600 genes Stockholm, May 1st, 2020 – Swedish biotechnology company CARTANA today announced the launch of a new range of In Situ Sequencing (ISS) reagent kits designed to increase the efficiency and enable ISS on virtually any tissue sample.

Combining the Powers of Single Cell Sequencing and AI in Understanding Disease Biology and Drug Development

XTalks

The detailed complexity of these processes can be captured by creating models that combine correlates of gene and protein expression, providing insight into the molecular composition of tissues. Visium Spatial Gene Expression Solution.

Epigenetic Therapeutic Targets Summit

Pharma Phorum

Join the Epigenetic Therapeutic Targets Summit – the only virtual summit dedicated to the clinical translation and optimization of therapeutic candidates targeting epigenetic mechanisms of gene expression.

Novel artificial genomic DNA can replicate and evolve outside the cell

Scienmag

Professor Norikazu Ichihashi and his colleagues at the University of Tokyo have successfully induced gene expression from a DNA, characteristic of all life, and evolution through continuous replication extracellularly using cell-free materials alone, such as nucleic acids and proteins for the first time.

DNA 83

How alike are the cancer cells from a single patient?

Scienmag

To carry out these behaviors, each cancer cell uses its genes to make the needed molecules in a unique way known as its “gene expression signature.”

Bioengineers learn the secrets to precisely turning on and off genes

Scienmag

Credit: Thomas Gorochowski In a recent study led by the University of Bristol, scientists have shown how to simultaneously harness multiple forms of regulation in living cells to strictly control gene expression and open new avenues for improved biotechnologies.

On the Heels of $46.7 Million Financing, Glympse Bio Announces Positive Data for NASH Sensors

BioSpace

Glympse Bio’s novel injectable mixture of synthetic sensors, which quantify protease activity and predict treatment response in non-alcoholic steatohepatitis (NASH), was demonstrated as safe and well-tolerated in healthy volunteers in a gene expression study of advanced fibrosis

Hackensack Meridian CDI scientists find one-two punch for preclinical cancer models

Scienmag

New cellular atlas maps out healthy and cancerous breast tissue

Scienmag

The research, which relied on expertise spanning from breast cancer biology through to bioinformatics, measured gene expression in single cells taken from healthy women and cancerous breast tissue, including […].

Solving ancient problem of nucleic acid synthesis helps to design new antiviral drugs

Scienmag

An international team of scientists from the University of Turku, Finland and PennState University, USA have solved a long-standing mystery of how living organisms distinguish RNA and DNA building blocks during gene expression paving the way for the design of new antiviral drugs.

Three-nation research to examine relationships between social factors and epigenetics

Scienmag

million National Institute on Aging grant to USC’s Eileen Crimmins supports collaboration of large studies in US, Republic of Ireland and Northern Ireland to answer questions about how life circumstances affect gene expression and health. A new three-nation project will examine how social, economic, psychological, environmental and behavioral circumstances in childhood influence gene expression […].

New drug inhibits the growth of cancer cells

Scienmag

Blocking gene expression in mitochondria in mice stops cancer cells from growing Credit: Hauke S. Hillen A newly developed compound starves cancer cells by attacking their “power plants” – the so-called mitochondria.

Basic cell health systems wear down in Huntington’s disease, novel analysis shows

Scienmag

Mathematics Computer Science Genes Genetics Mathematics/Statistics Medicine/Health Mental Health Molecular Biology Neurobiology

Molecular changes in white blood cells can help diagnose ‘the bends’ earlier in divers

Scienmag

First study to show gene expression changes in divers with ‘the bends’ reveals key role of genes for inflammation and immunity For over a century, researchers have known about “the bends”, a serious condition affecting scuba divers.