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Nitrogen-producing process of anammox bacterium finally uncovered

Scienmag

The anammox bacterium and other bacteria use this enzyme to convert toxic nitrite into nitrate. After years of research, the molecular structure of the enzyme responsible for a large part of the global nitrate and nitrogen production by bacteria has finally been uncovered.

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Patients with kidney transplants more vulnerable to common, usually harmless bacterium

Scienmag

11, 2021) – It’s a pervasive bacterium found in soil and water that rarely causes disease, but a new national review of nocardia infection in people who have had a kidney transplant shows that when it occurs it most commonly causes pneumonia and brain abscess, and reminds their physicians to stay on the […]. AUGUSTA, Ga.

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Common bacteria modified to make designer sugar-based drug

Scienmag

— Envisioning an animal-free drug supply, scientists have — for the first time — reprogrammed a common bacterium to make a designer polysaccharide molecule used in pharmaceuticals and nutraceuticals. Process paves a road to safe, ethical, and fast drug manufacturing Credit: Rensselaer Polytechnic Institute TROY, N.Y.

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MIT Scientists Develop Food Sensor That Can Detect Spoiled or Contaminated Food

XTalks

MIT engineers have designed a food sensor , made from an array of silk microneedles, that can pierce through the plastic packaging of foods to sample for bacterial contamination and spoilage. The strip did indeed work, showing a positive for the bacterium in about 16 hours and indicating spoilage a few hours after that.

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Non-vaccine nasal spray could protect against COVID-19

pharmaphorum

The spray is based on the SporeVax technology developed at Sporegen by Royal Holloway University Professor Simon Cutting and takes the form of heat killed spores of a bacterium – Bacillus subtilis – that stimulate a part of the innate immune system known as mucosal immunity.

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Global advances in synthetic biology

Drug Discovery World

The rapidly growing area of synthetic biology – including molecular biology, biotechnology, biophysics, and genetic engineering – is having a marked impact on the drug discovery landscape. In the UK, work being carried out at Imperial College 4 has seen the engineering of designer cells which could help advance treatment for disease. .

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Synlogic preps phenylketonuria drug for phase 3 after mid-stage win

pharmaphorum

Now, Synlogic has reported phase 2 results of two non-absorbed strains of the bacterium Escherichia coli Nissle used as probiotics – codenamed SYNB1618 and SYNB1934 – which have been engineered to break down phe in the gastrointestinal tract.

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