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Evaluating methods targeting Protein-Protein Interactions

pharmaphorum

Critical cellular processes including DNA replication and translation cannot occur without functional-specific proteins. Whereas targets like receptors contain an obvious ligand-binding site for drug molecules to interact with, PPIs comprise a more complex structure. Current challenges and conventional approaches in targeting PPIs.

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Can artificial intelligence help craft new medicines?

Drug Discovery World

Here, new bioassay technologies helped testing, but more definite answers were required. Recombinant DNA technology and improved protein purification techniques further contributed to our understanding and explorations of drug targets. Thus, there was a dire need for new and effective drug targets.