Pharmaceutical Technology

FEBRUARY 15, 2023

Another area where we tend to see problems is in encapsulation efficiency,” says Andrew Kondratowicz, Bioassay Team Lead, Precision NanoSystems. The bioassays are the canary in the coal mine of how well your process development is going. Where is your payload? Where is it allocated?

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Bioassay Development RNA Drugs 130

Drug Discovery World

APRIL 4, 2024

It will take place on 2 May at 3pm BST, 10am EDT, 4pm CEST and will presented by Ron Morena, Manager in Analytical Bioassay at Tanvex Biopharma CDMO, along with and Dr Neha Mishra, Senior Scientist in the BioProduction R&D team, Revvity.

Bioassay 52

Bioassay Antibody Drug Delivery Scientist 52

Drug Discovery World

APRIL 10, 2024

It will take place on 2 May at 3pm BST, 10am EDT, 4pm CEST and will be presented by Ron Morena, Manager in Analytical Bioassay at Tanvex Biopharma CDMO, along with and Dr Neha Mishra, Senior Scientist in the BioProduction R&D team, Revvity.

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Development Bioassay Antibody Drug Delivery 40

Pharmaceutical Technology

OCTOBER 12, 2022

As part of the collaboration, Toregem will use WuXi Biologics’ integrated CMC services in cell culture development, cell line development, bioassay development, biologics GMP manufacturing, cell banking and testing services, as well as other related services.

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Antibody Development Bioassay Manufacturing 130

BioTech 365

AUGUST 5, 2021

Magenta Therapeutics Reports Second Quarter Financial Results and Recent Program Highlights Magenta Therapeutics Reports Second Quarter Financial Results and Recent Program Highlights – Progress in addressing the FDA’s recommendations regarding bioassay and dose escalations to clear the current clinical hold … Continue reading →

Bioassay 52

Bioassay 52

Drug Discovery World

MARCH 4, 2024

By effectively running bioassays and analysing results, drug developers can efficiently optimise lead compounds, predict in vivo efficacy, and gain insights into the mechanism of action. RA: What are the current limitations of the standard practice for describing bioassay protocols?

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Drugs Bioassay Scientist In-Vivo 59

pharmaphorum

JANUARY 21, 2021

View the full event guide here to see the full agenda, speaker faculty and more! The post Gene Therapy Comparability appeared first on.

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Gene Therapy Gene Bioassay Manufacturing 52

pharmaphorum

SEPTEMBER 26, 2022

Whether you are focusing on specific characterization methods, enhancing your genome sequencing, advancing your understanding of full and partial particles, or advancing your early-stage bioassays, with 4 tracks, 8 pre-conference workshops, and a post-conference focus day, the 4 th Gene Therapy Analytical Development Summit will encompass all aspects (..)

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Gene Therapy Gene Development Bioassay 52

Drug Discovery World

AUGUST 1, 2023

Using multiple bioassays to gain insights on the effects of the CATCH regimen on different types of immune cells, the researchers showed that their strategy not only reactivated the cycle but also removed obstacles at other stages. The researchers named their approach CATCH.

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RNA Bioassay Genome Genomics 52

Drug Discovery World

MARCH 8, 2023

New projects will sit alongside the Alliance’s current portfolio of projects, now overseen by Dr Hall, which includes the IDMP Ontology Project, DataFAIRy Bioassay Annotation Project and Diversity & Inclusion in STEM Leadership program. A global initiative The inaugural meeting of the Council took place in January 2023.

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Life Science Bioassay Scientist Research 52

Roots Analysis

JANUARY 16, 2023

Cell and Gene Therapy Bioassay Services Market, 2021-2030. Further, owing to the various advantages offered by the AHST, such as cost effectiveness, the demand for such kits is likely to increase in the coming years. You may also be interested in the following titles: Targeted protein degradation market , 2022-2035. Our Social Media Platform.

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Bioassay Gene Editing Marketing Gene Therapy 52

pharmaphorum

AUGUST 5, 2021

It is a popular method in systems biology, requiring fewer compounds to be screened in bioassays, reducing time and cost. From here, the binding sites are classified into two categories which determine whether a structure- or ligand-based approach is required.

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Protein Gene Bioassay DNA 126

Drug Discovery World

FEBRUARY 23, 2023

SLAS 2023 Supplement, Volume 24 – Issue 1, Winter 2022/2023 About the authors Yue Liu is an Associate Director leading the bioassay innovation and discovery team at Generate Biomedicines.

Protein 52

Protein Life Science Bioassay Development 52

Drug Discovery World

JANUARY 19, 2023

However, standard technologies used to ensure the highest value cells are progressed require multistep operations and instruments, extensive hands-on time, and lengthy liquid handling processes, as well as complex, low throughput bioassays for functional validation and verification.

Engineer 52

Engineer Bioassay Life Science Genome 52

Drug Discovery World

AUGUST 12, 2022

millimolar solution for a bioassay or a milligram amount of a reactant for a synthesizer could have detrimental skewing effects on a derived dose response curve or could lead to an unbalanced reaction. Weighing out a sample based on the wrong molecular weight to create a 0.1 Figure 3 – Google Search for a Salt Molecular Weight.

Drugs 52

Drugs Bioassay Development Research 52

Drug Discovery World

MAY 4, 2023

Here, new bioassay technologies helped testing, but more definite answers were required. Expression patterns, proteomic profiles, bioassay results, and structures could now be captured en masse in normal and disease conditions. Thus, there was a dire need for new and effective drug targets.

Medicine 52

Medicine Protein Drugs Bioassay 52

Drug Discovery World

MAY 10, 2023

Carcinogenicity testing For decades, the two-year rodent bioassay has been the regulatory standard used to determine the carcinogenic potential of new drugs. This process historically involved lifetime carcinogenicity bioassays in two species. Figure 1: Comparing Carcinogenicity Testing Timelines in Transgenic vs. Standard Mice.

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Bioassay Genotoxicity Drugs In-Vivo 52

Drug Discovery World

NOVEMBER 30, 2023

Promega had two posters from which to share insight, which included: ‘Cell-based luminescent reporter bioassays for immunotherapies targeting macrophage effector functions’, and ‘Development of bioluminescent no-wash Fc gamma receptor binding immunoassay to guide the development of antibody therapeutics’.

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Antibody Protein Engineer In-Vivo 59

Drug Discovery World

NOVEMBER 9, 2023

Advances in analytical techniques and approaches This session is made up of four presentations which include: Christian Graf, PhD, Fellow, Scientific Office, Novartis TRD Biologics, on: ‘MS-based cell bioassays: A novel tool for biotherapeutics characterisation’.

Engineer 52

Engineer Antibody Protein In-Vivo 52

The Pharma Data

MAY 13, 2021

Aspartame bioassay findings portend human cancer hazards. Huang D, Dhawan T, Young S, et al. Fructose impairs glucose-induced hepatic triglyceride synthesis. Lipids Health Dis. 2011;10:20 DOI: 10.1186/1476-511X-10-20 . Huff J, LaDou J. Int J Occup Environ Health. 2007 OctDec;13(4):446-8. DOI: 10.1179/oeh.2007.13.4.446 2007.13.4.446 .

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Insulin Production Hormones Medicine 52

Pharmaceutical Technology

JANUARY 6, 2023

Cambrex performs validated IVRT on product development batches and also offers a range of bioassays to demonstrate product potency when applicable. Microbial bioassay – measures the potency of a biological active substance (e.g., Bioburden and microbial testing. an antibiotic).

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Production Manufacturing Development Bioequivalency 130