Cloudbyz

MARCH 5, 2024

The complexities in clinical research in both Clinical research for both biologics and small molecules involves complex processes that are crucial for demonstrating safety, efficacy, and quality before obtaining regulatory approval. Enhancing bioavailability is often a key focus in the development of small molecule drugs.

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Development Drugs Manufacturing Immune Response 78

Roots Analysis

MARCH 2, 2022

However, it is important to highlight that there are still several challenges which need to be addressed in order to develop biologic drugs capable of effectively being administered via the oral route without undergoing significant losses in specificity and / or bioavailability. Oral Protein / Peptide-based Drugs.

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Protein Drug Delivery Drugs Drug Delivery Systems 52

The Pharma Data

MARCH 11, 2021

Session Category: Clinical Research (Excluding Trials). Session Title: Disease-Oriented Innovative Clinical Research and Trials. Session Type: Clinical Trials Minisymposium. Abstract Number: 442. Session Title: Combination Immunotherapies. Session Type: E-Poster Session. Sintilimab. Abstract Number: CT041.

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Research Clinical Trials Clinical Trials Trials 52

Drug Discovery World

JULY 25, 2023

The final section provides practical and pragmatic approaches to clinical study design in paediatric patients including important considerations regarding dose formulation and selection, sample size, sample collection and analysis, relative bioavailability, food interactions and drug-drug interactions (DDIs), amongst others.

Development 52

Development Drugs Medicine Production 52

Pharmaceutical Technology

NOVEMBER 24, 2022

Understanding how a drug will act in the body, including how it is absorbed, distributed, and eventually eliminated, is a crucial component of drug research. Well-planned ADME investigations are conducted in the early stages of clinical research to generate this important data, which is needed for regulatory submissions.

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Bioavailability Manufacturing Drugs Production 130

Pharmaceutical Technology

FEBRUARY 13, 2023

At Quotient Sciences, our drug development consultants use our 30+ years of experience in clinical research outcomes to profile each new molecule that we look at. Quotient Sciences was asked to select the best candidate based on material science and oral bioavailability considerations.

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Development In-Vivo Clinical Trials Clinical Trials 130

XTalks

AUGUST 30, 2022

Clinical research experts from the CRO Medpace shared insights about the operational and regulatory considerations for neuroscience trials with direct CNS administration. Consider targeting your therapies that fail to be orally bioavailable and brain penetrant. The patients are waiting!

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Trials Drug Delivery Drugs Gene 83