The Pharma Data

DECEMBER 15, 2020

As the world’s first PPAR pan agonist that completed two confirmatory phase III clinical trials, Chiglitazar Sodium has shown significant and long-lasting hypoglycemic effects in a series of clinical studies, as well as other comprehensive effects including significant insulin sensitization and blood lipid regulation.

Insulin 40

Insulin Drugs Production Clinical Trials 40

The Pharma Data

DECEMBER 15, 2020

The Phase III trial evaluated the use of the diabetes vaccine Diamyd ® , an antigen-specific immunotherapy based on the auto-antigen GAD (glutamic acid decarboxylase), to induce immunological tolerance and stop the autoimmune destruction of insulin producing cells. People with type 1 diabetes cannot produce insulin.

Development 40

Development Insulin Drugs Clinical Trials 40

Pharmaceutical Technology

JANUARY 30, 2023

The drug increases insulin synthesis and release. Mounjaro heavily relied on CROs during its development, as evidenced by the fact that it has an associated 36 clinical research agreements recorded on GlobalData’s Deals database, suggesting that it may also turn to contractors for manufacturing.

Drugs 130

Drugs Manufacturing Contract Manufacturing FDA Approval 130

The Pharma Data

FEBRUARY 18, 2022

Depending on the infrastructure, workforce and clinical research and regulatory capacity in place, WHO and partners will work with the beneficiary countries to develop a roadmap and put in place the necessary training and support so that they can start producing vaccines as soon as possible. .”

Vaccination 52

Vaccination Vaccine Manufacturing Production 52

pharmaphorum

JUNE 14, 2021

This can lead to metabolic abnormalities including insulin resistance, diabetes, and elevated levels of blood lipids (such as high cholesterol). Partial lipodystrophy results in a partial loss, but the fat that remains is redistributed in inappropriate places around the body.

Drugs 105

Drugs Pharma Companies Licensing Licensing 105

Pharmaceutical Technology

JANUARY 10, 2023

Hailed as a breakthrough, Tzield’s approval marks the first of its kind to be introduced since the discovery of insulin, which won the 1923 Nobel Prize in the category of Physiology or Medicine. These therapies work by reprogramming the immune system, preventing it from attacking and eradicating insulin-producing cells in the pancreas.

Insulin 246

Insulin FDA Approval Research Clinical Trials 246

XTalks

APRIL 29, 2021

Maislin points to the lack of participant diversity in clinical trials conducted by Gilead Sciences for its COVID-19 treatment Veklury (remdesivir) as one example of this issue. If the people who would benefit most from a treatment aren’t included in clinical research, there’s a risk that drugs won’t be effective for that patient population.

Clinical Trials 95

Clinical Trials Clinical Trials Trials Drugs 95

The Pharma Data

DECEMBER 13, 2020

7.1%) levels were well controlled, and in this context, significant placebo-adjusted decreases were observed in both glycemic parameters along with improvements in commonly used fasting indexes of insulin sensitivity (HOMA-IR and QUICKI scores). Harrison, MD, Director, Summit Clinical Research. .

Trials 52

Trials In-Vitro Insulin Protein 52

pharmaphorum

SEPTEMBER 1, 2020

The first was insulin – Frederick Banting and colleagues managed to isolate insulin that could treat diabetes, up until that point a fatal condition. The period between 1918 and 1939 was marked by two breakthroughs that presaged the arrival of the pharma industry as we know it today.

Medicine 145

Medicine Insulin Pharmacy Drugs 145

XTalks

SEPTEMBER 17, 2020

While clinical researchers occasionally need to identify and validate a new surrogate endpoint for a given trial, choosing endpoints that have been previously used as the basis of NDAs and BLAs can clear the path to eventual approval. Also known as Berardinelli-Seip syndrome, there are four subtypes of lipodystrophy.

Trials 98

Trials Gene Hormones Clinical Trials 98

The Pharma Data

MAY 13, 2021

Insulin Resistance and Cancer Risk: An Overview of the Pathogenetic Mechanisms. Experimental Diabetes Research. Ectopic lipid storage and insulin resistance: a harmful relationship. Relationship between disease severity, hyperinsulinemia, and impaired insulin clearance in patients with nonalcoholic steatohepatitis.

Insulin 52

Insulin Production Hormones Medicine 52

The Pharma Data

APRIL 4, 2023

Merck has the industry’s largest immuno-oncology clinical research program. The KEYTRUDA clinical program seeks to understand the role of KEYTRUDA across cancers and the factors that may predict a patient’s likelihood of benefitting from treatment with KEYTRUDA, including exploring several different biomarkers.

FDA Approval 40

FDA Approval Containment Hormones Dermatology 40