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What to expect from drug discovery and development in 2023

Drug Discovery World

JANUARY 26, 2023

Opportunities will progress for use cases such as cancer diagnoses based on liquid biopsies, predicting cancer progression and improving gene editing tools potential (e.g. We are seeing the change from traditional biopharmaceuticals to cell and gene therapies. They will allow us to treat a disease with one single dose.

Development 98
Development Drugs Clinical Trials Clinical Trials 98
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Re-assessing the risks of drug-induced arrhythmias during drug discovery

Drug Discovery World

AUGUST 15, 2023

Dofetilide was found to inhibit the human Ether-à- go-go-Related Gene (hERG) encoding cardiac potassium channel, which mediates the repolarising current in the cardiac action potential (IKr). Inhibition of hERG can lead to one of the most lethal arrhythmias, known as torsade de pointes.

Drugs 52
Drugs In-Vivo Development Research 52
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