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Rheumatoid arthritis treated with implanted cells that release drug

The Pharma Data

Louis have genetically engineered cells that, when implanted in mice, will deliver a biologic drug in response to inflammation. “We used CRISPR technology to reprogram the genes in stem cells. The approach allows those cells to remain in the body for a long time and secrete a drug whenever there is a flare of inflammation.”

Drugs 52
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The Power of Lipids: Enhancing Drug Delivery with Nanoparticles

Roots Analysis

LNPs comprise of a lipid bilayer that surrounds a hydrophobic core, which can be loaded with therapeutic agents ( such as drugs, genetic material and proteins ). The average size of LNPs typically ranges from 40 to 1,000 nanometers, which allows efficient cellular uptake and intracellular delivery.

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Considerations for Neuroscience Trials with Intrathecal Delivery and Other Methods of Direct CNS Administration

XTalks

We know that a lot of different pathologies, especially as we’ve entered the era of molecular medicine and gene therapies, cause many of the same symptoms and work through final common pathways. Viral Vectors for Gene Delivery to the CNS. Next Steps for Targeted CNS Delivery. The patients are waiting!

Trials 83
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Metabolomics: An Emerging yet Powerful Tool in Clinical Research and Development

Roots Analysis

Genomics is the study of genetic material within a cell, and transcriptomics is the study of gene activity in different cells. This approach is often employed to determine the effect of genetic modifications or therapeutics in pharmacokinetic studies of drug metabolism. Untargeted Metabolomics. Our Social Media Platform.

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Covid-19 vaccine success bolsters nanoparticle drug delivery research

Pharmaceutical Technology

In an email to this news service, João Conde, PhD, professor at NOVA Medical School, Universidade NOVA de Lisboa, said advances like the mRNA vaccines serve as a testament to the breakthroughs made by science over decades of research at the junction of genetics and nanomedicine. These could feature in the next four to five years.