article thumbnail

A protein-based COVID-19 vaccine that mimics the shape of the virus

The Pharma Data

Even as several safe and effective COVID-19 vaccines are being administered to people worldwide, scientists are still hard at work developing different vaccine strategies that could provide even stronger or longer-lasting immunity against SARS-CoV-2 and its variants.

Protein 52
article thumbnail

Chemical found in leafy greens shown to slow growth of COVID-19 and common cold viruses

The Pharma Data

In a study described March 18 in the Nature journal Communications Biology, the scientists showed that sulforaphane, a plant-derived chemical, known as a phytochemical, already found to have anti-cancer effects, can inhibit the replication of SARS-CoV-2, the coronavirus that causes COVID-19, and another human coronavirus in cells and mice.

Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

Closing the translation gap in oncology drug development

Drug Discovery World

Mice and humans share the same set of organs and over 85% of their genetic makeup, which enables researchers to study interdependent biological consequences of genetic variation and clinical responses to anti-cancer compounds before advancing to human clinical trials. Cancer is far more complex than the sum of its parts.

article thumbnail

Roche launches SARS-CoV-2 variant test to help monitor emerging coronavirus mutations

The Pharma Data

This research use only laboratory test can be used to help scientists track mutation prevalence and to assess any potential impact on diagnostics, vaccines and therapeutics, providing crucial insight for healthcare systems in making appropriate measures to combat COVID-19. 1.1.7), South Africa (B.1.351), 1.351), and Brazil (P.1). 1.351 and P.1

article thumbnail

How mice with humanised immune systems are advancing cell-based immunotherapy

Drug Discovery World

By Courtney Ferrebee, PhD, Field Applications Scientist, Taconic Biosciences. As a result, researchers are striving to continually improve immuno-oncology approaches using the patient’s own immune cells to combat tumours. However, adverse effects such as cytokine release syndrome (CRS) and neurotoxicity still occur.

In-Vivo 52
article thumbnail

What to expect from PEGS Europe 2023: Day 1

Drug Discovery World

Sebastian Jaeger, PhD, Senior Scientist, ADCs & Targeted NBE Therapeutics, Merck Healthcare KGaA, on: ‘Evaluation of Fcab-drug conjugates as a novel antibody-based format for targeted drug delivery’.

article thumbnail

The evolution of assays for immuno-oncology research

Drug Discovery World

Cancer is a complex heterogenous multistep disease characterised by uncontrolled cell proliferation combined with a dysregulated immune response. A healthy immune system is naturally primed to eliminate malignant and abnormal cells through a synchronised and dynamic interplay between adaptive and innate immunity.