Rethinking Clinical Trials

MARCH 1, 2023

For the standard of care arm, treatment is determined by the treating investigator and participant, with the recommendation that the choice of drug is based on NCCN guidelines and dosing administration based on the participant’s previous therapy and disease. – What was the rationale for the choice of study treatments (i.e.,

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Rethinking Clinical Trials

JULY 13, 2023

This is compelling evidence that patients with HFrEF should be treated with this combination of therapies, but less than 5% of patients on are optimal guideline therapies for this condition.

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Rethinking Clinical Trials

OCTOBER 19, 2022

There are additional complexities with pragmatic clinical trials (PCTs), including overlapping roles and responsibilities of clinical and research staff; collection of broad sets of CDEs can make data monitoring more challenging; various and combined methods for data collection (e.g. Wilson Family Chair in Medicine. Ethics, IRB, FM-TIPS.

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