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Grand Rounds October 20, 2023: A National Initiative to Eliminate Hepatitis C in the United States – Why This Matters to Clinical Trialists (Rachael L. Fleurence, PhD, MSc; Joshua M. Sharfstein, MD)

Rethinking Clinical Trials

Fleurence, PhD, MSc Senior Advisor National Institutes of Health Joshua M. To address this crisis, the NIH is embarking on a National Initiative on Hepatitis C.       Speakers Rachael L. with the rate of reported acute Hepatitis C cases increasing 400% during 2010-2020. Rates are the highest among 20-39-year-olds.

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Grand Rounds July 8, 2022: Results From the COVID-OUT Trial, A Phase-3 Trial of Outpatient Treatment for Covid-19 Using Metformin, Ivermectin, and Fluvoxamine (Carolyn Bramante, MD, MPH; Thomas Murray, PhD; Jared Huling, PhD)

Rethinking Clinical Trials

Core Faculty, Program for Health Disparities Research. University of Minnesota School of Public Health. University of Minnesota School of Public Health. Some aspects were a success, particularly delivery of study medication nation-wide within 1 day of consent. University of Minnesota Medical School. Thomas Murray, PhD.

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Grand Rounds August 19, 2022: Inclusion and Diversity in Clinical Trials: Actionable Steps to Drive Lasting Change (Gerald Bloomfield, MD, MPH; Michelle Kelsey, MD)

Rethinking Clinical Trials

Associate Professor, Global Health. There is a national priority to increase diversity in clinical trials, from regulatory, funding agencies, industry, and others, so that the participant population reflects the U.S. This is an issue that a number of institutions have been thinking about for some time. Michelle Kelsey, MD.

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Grand Rounds October 6, 2023: Hybrid Studies Should Not Sacrifice Rigorous Methods (David M. Murray, PhD; Moderator: Jonathan Moyer, PhD)

Rethinking Clinical Trials

Moyer, PhD Statistician, NIH Office of Disease Prevention Slides Keywords Implementation; Study design; Hybrid; Clustered; DECIPHeR Key Points People often contest that hybrid designs are not as rigorous as they should be. To the extent that you can use data from electronic health records, that will help with keeping the staff blinded.

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Novel method predicts if COVID-19 clinical trials will fail or succeed

Bioengineer

As of July 15, more than 6,180 COVID-19 clinical trials have been registered through ClinicalTrials.gov, the national registry and database for privately and publicly funded clinical studies conducted around the world. The study was funded by the National Science Foundation awarded to Zhu. ” ###.

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Grand Rounds February 17, 2023: The Heartline Trial: A New Paradigm in Conducting Virtual Clinical Trials (C. Michael Gibson, MS, MD)

Rethinking Clinical Trials

The study is enrolling people where they are using social media, such as Facebook ads, twitter influencers, tv ads, interviews with print/electronic news outlets, national tv (an appearance on “The Talk” to discuss the study), targeted advertising, physicians, electronic health records. There was news pushed out about general health.