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Gene Silencing Porphyria Treatment, Givlaari, Finally Wins Over England’s NICE Amid Stellar Long-Term Data

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AIP is a type of acute hepatic porphyria (AHP) that can cause severe pain and neurological symptoms, including seizures, due to a buildup of toxic neuroproteins. The treatment came with an initial price tag of $39,000 per vial, which amounts to a total of $575,00 each year. This leads to lowering of ALA and PBG levels.