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Enough Of Wasting Away From Cancer: Companies Gear Up To Tackle Cachexia

Delveinsight

Cachexia is observed as a result of underlying diseases, including cancer, AIDS, tuberculosis, chronic heart failure, hormonal deficiency, and others. NGM120 is a first-in-class antagonistic antibody, which binds glial cell-derived neurotrophic factor receptor alpha-like (GFRAL) and inhibits growth differentiation factor 15 (GDF15).

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Big pharma vs small diseases: Tackling rare diseases

pharmaphorum

Despite the inherent difficulties, major pharma companies do take aim at rare diseases, usually with dedicated units focusing on clusters of rare diseases that afflict the same part of the body. How big pharma tackles rare diseases. It’s a different business model, if you will,” Miquel said. “So So that is the trick.

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2020 review – Pharma’s progress outside of COVID-19

pharmaphorum

The company’s menopause drug NT-814 is heading for phase 3 development in 2021 following a mid-stage trial readout. NT-814 is a non-hormonal drug that works on the neurokinin (NK) 1,3 receptor antagonist, thus treating the vasomotor symptoms associated with the menopause. Rare disease progress.

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Unfolding The Folds Of Transthyretin

Delveinsight

Transthyretin (TTR) is a protein that the liver produces to facilitate the transfer of thyroid hormone and vitamin A in the blood. Pharma companies like Alnylam Pharmaceuticals , Ionis Pharmaceuticals , Eidos Therapeutics, and many others are providing the thrust to the Hereditary transthyretin amyloidosis market forward.

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Protein Precision: “Harnessing Targeted Protein Degradation”

Roots Analysis

Due to which, several big pharma companies and other industry stakeholders are actively contributing towards development of protein degradation therapies and technologies, contributing towards growth of targeted protein degradation market.

Protein 40
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Rheumatoid Arthritis: Causes, Risk Factors, Treatment Approaches and Market Landscape

Delveinsight

Even after several years of research, exact causes of Rheumatoid Arthritis are unknown, but some factors are believed that trigger the immune system to mistakenly send antibodies to attack the joints and the tissues surrounding them; which in turn results in pain and inflammation. These antibodies are signs of hyperactive immunity.

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BioSpace Global Roundup, Oct. 15

The Pharma Data

VBL Therapeutics – The European Patent Office granted a patent to Israel-based VBL’s proprietary investigational anti-MOSPD2 monoclonal antibodies to treat inflammatory conditions. VBL is currently advancing its lead anti-MOSPD2 candidate through IND-enabling studies.