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US researchers decipher how one gut bacterium influences immunity

Drug Discovery World

But with hundreds of bacterial species populating our gastrointestinal tract, it’s a daunting task to pinpoint which molecules made by which bacteria affect which biological processes—and how they do so. Such knowledge is essential for learning how to manipulate gut bacteria to treat or prevent illness. Funding and authorship.

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Stanford researchers construct the most complete synthetic microbiome

Drug Discovery World

Fischbach, who is an Associate Professor of Bioengineering and of Microbiology and Immunology, and others saw one solution: Build a microbiome from scratch by growing individually and then mixing its constituent bacteria. They introduced hCom1 to mice that are carefully designed to have no bacteria present. Building the ark.