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US researchers decipher how one gut bacterium influences immunity

Drug Discovery World

But with hundreds of bacterial species populating our gastrointestinal tract, it’s a daunting task to pinpoint which molecules made by which bacteria affect which biological processes—and how they do so. Such knowledge is essential for learning how to manipulate gut bacteria to treat or prevent illness.

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Cause of 1990s Argentina cholera epidemic uncovered

Scienmag

Work allows genomic monitoring for epidemic strains of Vibrio cholerae bacteria The evolution of epidemic and endemic strains of the cholera-causing bacterium Vibrio cholerae in Argentina has been mapped in detail by researchers at the Wellcome Sanger Institute, the London School of Hygiene and Tropical Medicine, the University of Cambridge and the (..)

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Anti-tumor agent from the intestine

The Pharma Data

We are talking about the microbiome – the vast collection of bacteria in the human gut. The microbiome has been the focus of research for 20 years – ever since a new technique made it possible to analyse these bacteria quickly and precisely: high-throughput sequencing. The immune system is mentioned particularly frequently.

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Stanford researchers construct the most complete synthetic microbiome

Drug Discovery World

Fischbach, who is an Associate Professor of Bioengineering and of Microbiology and Immunology, and others saw one solution: Build a microbiome from scratch by growing individually and then mixing its constituent bacteria. They introduced hCom1 to mice that are carefully designed to have no bacteria present. Building the ark.

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2020 Year in Review: COVID-19, CRISPR and Immunotherapies Define the Year for the Life Sciences

XTalks

From isolating SARS-CoV-2 in early January to sequencing its genome shortly thereafter and having a prototype vaccine against it within days, scientific process and progress have held steadfast throughout the pandemic. CRISPR are found in approximately 50 percent of sequenced bacterial genomes and nearly 90 percent of archaea genomes.