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US researchers decipher how one gut bacterium influences immunity

Drug Discovery World

But with hundreds of bacterial species populating our gastrointestinal tract, it’s a daunting task to pinpoint which molecules made by which bacteria affect which biological processes—and how they do so. Such knowledge is essential for learning how to manipulate gut bacteria to treat or prevent illness.

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Scientists discover small RNA that regulates bacterial infection

The Pharma Data

Scientists discover small RNA that regulates bacterial infection People with weakened immune systems are at constant risk of infection. But the bacteria can sometimes change their behavior and enter the bloodstream, causing chronic localized infections to become acute and potentially fatal. aeruginosa infections.

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Global advances in synthetic biology

Drug Discovery World

Its strategy is based on identifying, selecting, and nurturing high-quality European science and this model aims to bring together scientists from across Europe, combining tools and expertise from academia and industry. . It appears to neutralise even drug-resistant bacteria. . diff, and several other deadly pathogens.

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New Research Shows IBS Symptoms May be Caused by Gut Infections

XTalks

Through laboratory and clinical studies, the scientists discovered that blockade of histamine could help alleviate IBS symptoms. The mice were fed the protein again after the infection had been cleared, to see whether the infection had sensitized the immune system.

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Stanford researchers construct the most complete synthetic microbiome

Drug Discovery World

Rebecca McClellan, Scientific Program Manager, Research, Development & Communications, explains how scientists are learning more about the connections between the microbiome and human health to potentially develop first-in-class microbiome therapies. They introduced hCom1 to mice that are carefully designed to have no bacteria present.

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Top 30 Pharma and Biotech Companies in 2023: Statistics and Trends

XTalks

Johnson & Johnson’s Top 5 Best-Selling Drugs of 2022: 1) Stelara (ustekinumab) Stelara is an immunosuppressant biologic therapy that blocks the IL-12 and IL-23 proteins that play a role in plaque psoriasis and Crohn’s disease. The monoclonal antibody targets CD20, a protein found on the surface of B lymphocytes (B cells).

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2020 Year in Review: COVID-19, CRISPR and Immunotherapies Define the Year for the Life Sciences

XTalks

After being identified in December 2019 in Wuhan, Hubei in China, medical officials and scientists got to work to isolate and identify the novel virus that they observed to be causing a new respiratory illness. Most antibody drugs and vaccines have been developed to target parts of the spike protein.