Scienmag

APRIL 29, 2022

Department of Energy’s Brookhaven National Laboratory and their collaborators have discovered an aberrant protein that’s deadly to bacteria. In a paper just published in the journal PLOS ONE, the scientists describe how this erroneously built protein mimics the action of aminoglycosides, a class of antibiotics.

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Bacteria Protein Scientist 94

XTalks

JANUARY 12, 2022

A team of scientists from Harvard T.H. The innovative food packaging is made from a type of corn protein called zein , starch and other naturally-derived biopolymers, which have been found to be sustainable replacements for PFAS and other plastic-coated paper. So, how does it work? Coli or Listeria.

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Packaging Packaging Scientist Bacteria 98

Scienmag

OCTOBER 19, 2020

New research led by University of Hawai’i at Manoa scientists revealed that, in the mutually beneficial […]. It is now recognized that microbiomes are major drivers of health in all animals, including humans, and that these symbiotic systems often exhibit strong daily rhythms.

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Bacteria Protein Scientist Research 52

Scienmag

OCTOBER 27, 2020

Building the driving machinery of bacteria, the flagella, requires numerous proteins to be assembled. Adding sugar and the presence of a control point are two key steps identified by UNIGE scientists.

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Bacteria Protein Scientist 89

The Pharma Data

JUNE 14, 2023

Scientists discover small RNA that regulates bacterial infection People with weakened immune systems are at constant risk of infection. But the bacteria can sometimes change their behavior and enter the bloodstream, causing chronic localized infections to become acute and potentially fatal. aeruginosa infections.

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RNA Regulation Scientist Bacteria 40

Scienmag

MAY 21, 2021

Hansen DALLAS – May 21, 2021 – One member of a large protein family that is known to stop the spread of bacterial infections by prompting infected human cells to self-destruct appears to kill the infectious bacteria instead, a new study led by UT Southwestern scientists shows.

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Bacteria Protein Scientist Medicine 79

The Pharma Data

JUNE 30, 2021

For their remarkable scientific contributions, doctoral student Julia Klaus, Zurich University VetSuisse Faculty, and Dr Yasmin Parr from the MRC-University of Glasgow, Centre for Virus Research, have received the 2021 ABCD Young Scientist Award. To foster young talent development in the feline health research community.

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Scientist Immune Response Antibody Development 52

Delveinsight

JANUARY 28, 2021

Nirogy plans to use the proceeds to improve its drug discovery platform for generating a pipeline of small-molecule drugs designed to aim the solute carrier family of transporter proteins (SLCTs) embedded in the cell membrane. Gut Bacteria proffer insight into molecules protective against asthma and COVID-19.

Bacteria 52

Bacteria Trials Drugs Clinical Trials 52

Drug Discovery World

AUGUST 9, 2022

Based in Dundee, Cypex manufactures recombinant xenobiotic metabolizing enzymes with its product portfolio covering a wide range of proteins involved in drug metabolism. . This technology enables the expression of human drug-metabolizing enzymes in bacteria, without requiring large modifications to the proteins.?

In-Vitro 52

In-Vitro Protein Production Bacteria 52

XTalks

JANUARY 6, 2021

One nanobody in particular, called NIH-CoVnb-112, was shown to be able to prevent COVID-19 infection from the novel coronavirus by targeting both the spike protein on SARS-CoV-2, as well as the angiotensin converting enzyme 2 (ACE2) receptor that it binds to on human cells. Related: Scientists Use Llama Antibodies to Neutralize COVID-19.

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Antibody Protein Bacteria In-Vitro 105

The Pharma Data

JUNE 22, 2023

They have shown that the mechanism involves a block in proteins called interferons, which promote tissue factor releases. ” The team demonstrated that life-threatening clotting could be prevented in mice infected with the bacteria E. coli and Staph aureus and also in response to SARS-CoV2, the virus that causes COVID-19.

Bacteria 40

Bacteria Branding Protein Scientist 40

Drug Discovery World

NOVEMBER 17, 2022

Its strategy is based on identifying, selecting, and nurturing high-quality European science and this model aims to bring together scientists from across Europe, combining tools and expertise from academia and industry. . It appears to neutralise even drug-resistant bacteria. . diff, and several other deadly pathogens.

Bacteria 52

Bacteria Engineer Gene Genetics 52

Drug Discovery World

JULY 29, 2022

But with hundreds of bacterial species populating our gastrointestinal tract, it’s a daunting task to pinpoint which molecules made by which bacteria affect which biological processes—and how they do so. Such knowledge is essential for learning how to manipulate gut bacteria to treat or prevent illness.

Bacterium 52

Bacterium Research Bacteria Immune Response 52

Drug Discovery World

MARCH 14, 2023

For the first time, researchers have developed an mRNA vaccine that is 100% effective against a type of bacteria that is lethal to humans, paving the way for effective vaccination against antibiotic-resistant bacteria. However, until now scientists believed that mRNA vaccines against bacteria were biologically undoable.

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Bacteria Vaccination Vaccine Protein 59

The Pharma Data

MARCH 13, 2022

assistant professor of medicine at the Johns Hopkins University School of Medicine and staff scientist at NIAID. assistant professor of medicine at the Johns Hopkins University School of Medicine and staff scientist at NIAID. population.

Immune Response 52

Immune Response Protein Medicine Genetics 52

Drug Discovery World

DECEMBER 14, 2023

In addition, Glasgow is an attractive location to the brightest and best scientists from all over the world.  Its researchers represent some of the best scientists from around the world who have come together to work towards better outcomes for patients today and in the future.”

Drugs 75

Drugs Life Science Research Scientist 75

Drug Discovery World

FEBRUARY 6, 2024

Sanofi has stated that it intends to become the first pharma company “powered by AI at scale”, and as part of this ambition, agreed a collaboration with BioMap to co-develop advanced AI models and protein Large Language Models that that it hopes will enable biologics design and multiparametric optimisation 2. Obulytix is not alone.

Marketing 69

Marketing Medicine Genome Genomics 69

Drug Discovery World

DECEMBER 29, 2023

Dr Sofia Ferreira, Director of Applications at Refeyn, discusses how various technologies can address the main challenges in membrane protein characterization, describing how novel technologies, such as mass photometry, can streamline and support analytical processes. Scientists use a multitude of membrane mimetics to overcome this issue.

Protein 52

Protein In-Vitro Research Drugs 52

Pharmaceutical Technology

AUGUST 17, 2022

Lyme disease is also known as borreliosis, which refers to the borrelia bacteria that cause the condition. The vaccine targets six different serotypes of borrelia bacteria. In the past, the volatility of the bacteria made target identification difficult. It is currently treated with antibiotics.

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Vaccination Vaccine Bacteria Protein 299

XTalks

JANUARY 20, 2021

Through laboratory and clinical studies, the scientists discovered that blockade of histamine could help alleviate IBS symptoms. The mice were fed the protein again after the infection had been cleared, to see whether the infection had sensitized the immune system.

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Immune Response Research Allergies Protein 52

Roots Analysis

OCTOBER 19, 2023

Bacteria plays a crucial role in maintaining the ecosystem balance. However, there are few species of bacteria that can cause several infectious diseases ( such as strep throat, salmonellosis, tuberculosis, whooping cough ). The overuse of antibiotics has resulted in the emergence of multi-drug-resistant bacteria. coli and P.

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Bacteria Production In-Vivo In-Vitro 40

Drug Discovery World

NOVEMBER 28, 2023

Scientists at the University of Bath have developed a way of joining up the head and tail of a protein, making it more stable and easier to get into cells. Drug treatments often work by binding to proteins involved in disease and blocking their activity, which either reduces symptoms or treats the disease.

Protein 59

Protein Drugs Reagent Life Science 59

Drug Discovery World

OCTOBER 11, 2023

Dr Luke Clifton , Instrument Scientist at ISIS Neutron and Muon Source, explains the molecular mechanism behind antibiotics. The two main classes of bacteria are separated based on their differing cell surface architecture. The two main classes of bacteria are separated based on their differing cell surface architecture.

Bacteria 59

Bacteria Development Scientist Protein 59

Drug Discovery World

APRIL 30, 2024

Its job is to carry coding information that is essential to the translation and processing of functional proteins. This is essential to its use as a therapeutic agent and gives the technology a vast versatility making it suitable to treating a wide range of diseases – especially those that have high protein expression.

RNA 52

RNA Protein Vaccination Vaccine 52

Drug Discovery World

APRIL 25, 2024

Grand View Research states that the market for cell lines is currently bolstered by the fact that the majority of biopharma companies use cell lines to synthesise recombinant monoclonal antibodies and proteins. There are a lot of considerations to take when choosing a cell line.

Development 59

Development Protein In-Vivo Life Science 59

XTalks

FEBRUARY 11, 2021

Much of the fundamental groundwork for genetics and genomic research was laid in the 20 th century, with significant contributions from women scientists, some of whom worked during times when acceptance of female researchers was not widespread. Martha Chase: For the Books. Martha Chase. The marriage ended in divorce after a few short years.

Genetics 119

Genetics DNA Genome Genomics 119

XTalks

NOVEMBER 9, 2021

Ever since pesticides became widely used in agriculture, scientists have been searching for ways to improve upon pest protection for both human and planetary health. RNA interference (RNAi) is one such improvement that earned the scientists responsible for its discovery a Nobel Peace Prize in 2006. In 2017, Monsanto Co.

RNA 98

RNA Gene Scientist Protein 98

Drug Discovery World

AUGUST 10, 2022

The immune system typically identifies foreign entities such as bacteria and viruses and activates lymphocytes such as T cells to destroy them with overwhelming force. To overcome this evasion tactic, the CAR protein was developed to recognise other markers on cancer cells. Identifying the right CAR T cell target.

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Manufacturing Gene Genome Genomics 98

Drug Discovery World

OCTOBER 4, 2022

Rebecca McClellan, Scientific Program Manager, Research, Development & Communications, explains how scientists are learning more about the connections between the microbiome and human health to potentially develop first-in-class microbiome therapies. They introduced hCom1 to mice that are carefully designed to have no bacteria present.

Research 52

Research Bacteria Scientist Bacterium 52

Drug Discovery World

MAY 2, 2023

In the event of an attack from similar bacteriophages, the bacteria can recognise these segments and use this to discern and cleave the viral DNA, which disrupts the viral gene function. Scientists can now target, activate, or silence any genes of interest to perturb the phenotype of cell populations.

Genome 52

Genome Genomics Gene DNA 52

Delveinsight

JULY 23, 2020

In a new study that is published in Science Translational Medicine, the scientists showed that preventing a protein called PI3KC2a could alter how platelets react to a change in blood flow that can promote the formation of clots, which is a common cause of heart attack or stroke.

Protein 52

Protein Bacteria Scientist Research 52

pharmaphorum

SEPTEMBER 14, 2020

While there may be just under 20,000 confirmed protein coding genes, it turns out that much of the genome outside of these genes is also important in regulating how the genome is controlled. To address these issues, scientists and clinicians are starting to look at ‘long-read’ sequencing.

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Genome Genomics Medicine Gene 117

Druggist

SEPTEMBER 15, 2021

But, the way the virus is continuously mutating, is a problem for both scientists and doctors. This medicine inhibits the growth of bacteria by inhibiting the synthesis of essential proteins which is needed by the bacteria to carry out the necessary functions. Every effort is being made to prevent covid-19.

Doctors 52

Doctors Doctor Medicine Bacteria 52

Druggist

SEPTEMBER 15, 2021

But, the way the virus is continuously mutating, is a problem for both scientists and doctors. This medicine inhibits the growth of bacteria by inhibiting the synthesis of essential proteins which is needed by the bacteria to carry out the necessary functions. Every effort is being made to prevent covid-19.

Doctors 52

Doctors Doctor Medicine Bacteria 52

Drug Discovery World

JULY 18, 2023

Current research is focused on designing CRISPR-enhanced CAR T cells that are resistant to immunosuppressive cytokines such as transforming growth factor-β (TGF-β) 2 , programmed cell death protein (PD-1) 3 , or other negative T cell regulators 4 (CTLA-4, LAG-3, and TIM-3), thus improving anti-tumour functions.

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DNA Genome Genomics RNA 98

The Pharma Data

DECEMBER 15, 2020

Scientists will be testing a drug class targeting the C-reactive protein (CRP) marker of acute inflammation in the body. The protein may be involved in such conditions, and a CRP test may be used to find or monitor conditions that cause inflammation. Next, they plan on identifying potential therapeutic candidates.

Clinical Trials 52

Clinical Trials Clinical Trials Antibody Trials 52

The Pharma Data

JANUARY 21, 2021

Researchers at Stanford Medicine , investigating old mice and human cell cultures, found that immune cells called myeloid cells, which are found in the brain, circulatory system and peripheral tissues not only battle infectious agents, but work on cleaning up debris, like dead cells and aggregated proteins.

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Research DNA Hormones Vaccination 52