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Guide to using AAV vectors in gene therapy

Drug Discovery World

In 2023, DDW hosted a webinar, ‘A comprehensive guide to using adeno-associated virus (AAV) vectors in gene therapy’, supported by Azenta Life Sciences. Questions were fielded from the audience, which included: What analysis will be performed to evaluate host or other DNA contamination? Why are those important?

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Guide to using AAV vectors in gene therapy

Drug Discovery World

Earlier this year, DDW hosted a webinar, ‘A comprehensive guide to using adeno-associated virus (AAV) vectors in gene therapy’, supported by Azenta Life Sciences. Questions were fielded from the audience, which included: What analysis will be performed to evaluate host or other DNA contamination?

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Advances in cell line development

Drug Discovery World

The market for cell line development is currently rising due to an increased focus by the life sciences sector on biopharmaceuticals and targeted therapies. For instance, bacteria and yeast cell lines are easier to cultivate compared with mammalian cell lines, requiring less maintenance for the medium they are grown in.

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Improving quality control for CAR T cell therapies

Drug Discovery World

The immune system typically identifies foreign entities such as bacteria and viruses and activates lymphocytes such as T cells to destroy them with overwhelming force. Although this type of contamination has not yet been reported in humans, RCVs can form rapidly growing T cell neoplasms, another type of cancer. Marwan obtained his M.S.