The Genomic Medicine Revolution: Multi-Modality Approaches in Advanced Therapies
Pharmaceutical Technology
AUGUST 16, 2024
Genomic medicines offer new techniques for treating conditions once thought to be intractable - a world of opportunity awaits.
Genome Related Topics 
Tome Biosciences debuts with $213M and a new way to edit the genome
Bio Pharma Dive
DECEMBER 12, 2023
Based on the work of MIT scientists, the well-funded startup is developing ways to insert large sizes of genetic material anywhere in the genome without damaging or breaking DNA.
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AstraZeneca, seeking new drug targets, taps a genomics biotech and its AI technology
Bio Pharma Dive
SEPTEMBER 8, 2023
Worth up to $840 million, the collaboration will give Alexion access to Verge Genomics’ platform, which uses human tissue data to find drug targets for diseases that degrade the nerve system.
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Tome acquires startup Replace, gaining new genome editing tools
Bio Pharma Dive
JANUARY 2, 2024
The deal is the second startup sale engineered by University of California, Berkeley scientist Shakked Halperin, and gives Tome a way to insert or delete small DNA sequences into the genome.
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Analyze whole genome sequencing samples at the speed of light
Bio Pharma Dive
FEBRUARY 13, 2023
Deliver fast and reliable results at low cost with a tool for whole genome analysis in just minutes
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Hopewell Therapeutics raises funds for genomic medicines development
Pharmaceutical Technology
JUNE 8, 2023
Biotechnology company Hopewell Therapeutics has raised $25m in seed financing to accelerate the development of next-generation lipid nanoparticles for targeted delivery of genomic medicines. Hopewell Therapeutics is engaged in discovering, synthesising and developing advanced ttLNPs to provide next-generation genomic medicines.
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Access to genomic surveillance: Open science and public health
pharmaphorum
OCTOBER 16, 2024
The pandemic served as a catalyst for a revolution in genomic surveillance for tracking pathogens. The technology proved vital in aiding understanding of the evolution of and spread of virus in real time to inform public health measures, ultimately accelerating drug and vaccine development.
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The new genomic frontier: Next-generation data management takes flight
pharmaphorum
JUNE 21, 2024
Explore the latest advancements in genomics and sequencing technologies, and learn how next-generation data management tools are transforming genomic research and applications in this new genomic frontier.
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Short reads, big impact: How genomics is revolutionising cancer research
pharmaphorum
MAY 30, 2024
Discover how genomics is transforming cancer research through the study of DNA, RNA, and ctDNA. Learn about the latest breakthroughs in the field in this insightful short read.
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Data-driven disease research harnessing the genome
pharmaphorum
JANUARY 9, 2024
Discover how the UK Biobank is leveraging technology and the power of genomics in data-driven disease research. Join the digital revolution in understanding and combating diseases using cutting-edge techniques and large-scale genomic data analysis.
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Working for a mature form of genomic medicines
pharmaphorum
MAY 29, 2024
In a new episode of the pharmaphorum podcast, Rahul Kakkar, CEO of gene editing company Tome, speaks with web editor Nicole Raleigh about programmable genomic integration (PGI) technology.
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Royal Marsden launches first UK genome testing facility to improve testing for cancer
Pharma Times
JUNE 14, 2024
The installation will double the capacity of cancer genomic testing using robotic automation
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Genome Edited Foods: Understanding the New FDA Guidance
XTalks
MARCH 1, 2024
In a pivotal move for the food industry, the US Food and Drug Administration (FDA) has unveiled industry guidance for genome edited foods derived from plants. This landmark guidance aims to demystify the FDA’s risk-based approach towards both genome edited foods and all new plant varieties. What is Genome Editing?
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UK study backs whole-genome screening for cancer care
pharmaphorum
JANUARY 10, 2024
UK study led by Genomics England drawing on 100,000 Genomes Project and real-world clinical data backs use of whole-genome sequencing in cancer care
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Genome Research publishes a special issue in Single-cell Genomics
Scienmag
OCTOBER 1, 2021
October 1, 2021 – Genome Research ([link] publishes a special issue highlighting novel advances and insights in Single-cell Genomics. October 1, 2021 – Genome Research ([link] publishes a special issue highlighting novel advances and insights in Single-cell Genomics. Credit: Cover artwork © Victor O.
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A new dawn of the genomic age: five areas set to be transformed in 2023
pharmaphorum
JANUARY 26, 2023
2022 was a banner year for genomics. In March, the collaborative T2T consortium published the first complete telomere-to-telomere sequence of the human genome, filling in the last 8% of the 3 billion base pairs that make up our DNA.
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Magazine: Genomic projects exploit scale as clinical applications play catch-up
Pharmaceutical Technology
JULY 26, 2022
The last few months have marked the publication of research emerging from projects designed to collect and analyse genomic data on a wider scale than was previously thought possible. The post Magazine: Genomic projects exploit scale as clinical applications play catch-up appeared first on Pharmaceutical Technology.
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Experts prefer whole genome sequencing as viable option to identify & characterize bacteria as concerns of AMR escalate
AuroBlog - Aurous Healthcare Clinical Trials blog
DECEMBER 18, 2023
As antimicrobial resistance (AMR) poses a growing threat to global public health, challenging the effectiveness of antibiotics and other antimicrobial drugs, medical experts suggest whole genome sequencing as a viable option to identify and characterize the bacteria, viruses, fungi or parasites, along with their transmission pattern.
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Investment fuels AI-driven development of breakthrough genomic medicines
pharmaphorum
OCTOBER 12, 2022
David Del Bourgo (CEO and co-founder, Whitelab Genomics) has always been passionate about introducing disruptive, innovative technologies to markets. We founded Whitelab Genomics after realising the potential to use data, data science, and AI in a more systematic way to develop genomic therapies,” Del Bourgo says.
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Emmes and MedGenome Launch Genomics Strategic Partnership Focused on Advancing Rare Disease Research
Pharma Mirror
NOVEMBER 16, 2021
Rockville, Emmes, a global, full-service Clinical Research Organization dedicated to supporting the advancement of public health and biopharmaceutical innovation, today announced a partnership with MedGenome aimed at accelerating breakthrough treatments, powered by human genomics, for rare disease patients.
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Genomics England will move HQ to Canary Wharf’s new biocluster
pharmaphorum
JUNE 13, 2022
Canary Wharf’s bid to become a new hub for the life sciences sector in the UK has been given a boost following the decision by Genomics England to relocate to the development. Genomics England will move into space at the iconic One Canada Square skyscraper (pictured) that was the EMA’s home before the move to the Netherlands.
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STAT+: ??Genomics is racing toward a $100 genome. Are we ready for it?
STAT News
JULY 27, 2022
As the cost of DNA sequencing plummets, we’re fast approaching a point when decoding a human genome could cost $100 — about as much as the average American’s weekly grocery store run. Health systems are preparing to test programs that could lead to the use of whole-genome screening in millions of newborns.
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UK Biobank releases largest-ever genome sequencing dataset
pharmaphorum
NOVEMBER 30, 2023
UK Biobank releases largest-ever genome sequencing dataset Phil.Taylor Thu, 30/11/2023 - 10:00 Bookmark this
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How Hazel Jones is charting new horizons in genomics
BioPharma Reporter
MAY 15, 2024
Hazel Jones is the interim CEO and chief operations officer at Enhanc3D Genomics. We sat down with her to discuss her leap of faith into 3D genomics, and how she is scaling the business and driving operational change.
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GEN-001 by Genome & Co for Head And Neck Squamous Cell Carcinoma (HNSC): Likelihood of Approval
Pharmaceutical Technology
DECEMBER 4, 2023
GEN-001 is under clinical development by Genome & Co and currently in Phase I for Head And Neck Squamous Cell Carcinoma (HNSC).
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Congenica extends contract with Hong Kong Genome Project
BioPharma Reporter
OCTOBER 9, 2023
Congenica, a digital health company providing software and solutions for the analysis and interpretation of genomic data at scale, has announced a two-year extension to its contract for the Hong Kong Genome Project (HKGP), the first large-scale genome sequencing initiative in Hong Kong.
Large European study underlines power of genomic sequencing to diagnose diseases
STAT News
APRIL 12, 2023
LONDON — Using genome sequencing greatly expanded the number of diagnoses researchers could provide for children with developmental disorders from thousands of families across the United Kingdom and Ireland, researchers reported in a new study Wednesday. Read the rest…
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USDA-ARS releases genome of the voracious desert locust
Scienmag
JUNE 26, 2022
June 27, 2022–The first high-quality genome of the desert locust—those voracious feeders of plague and devastation infamy and the most destructive migratory insect in the world—has been produced by U.S. June 27, 2022–The first high-quality genome of the desert locust—those voracious feeders of […].
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As the Smithsonian wraps a landmark genome exhibit, leaders in the field reflect on what’s changed
STAT News
AUGUST 17, 2022
When the Smithsonian National Museum of Natural History opened its genomics exhibit in 2013, the field was just celebrating the 10th anniversary of the completed Human Genome Project. Sequencing that first genome cost over $500 million. The genomes since cost $10,000. The development of CRISPR-Cas9 landed a Nobel Prize.
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UK announces mass genome sequencing programme for newborns
Medical Xpress
DECEMBER 13, 2022
UK health authorities on Tuesday announced a pioneering research programme using the genomes of 100,000 new-born babies, to detect rare genetic illnesses and speed up treatment.
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Personalising whole genome sequencing doubles diagnosis of rare diseases
Medical Xpress
NOVEMBER 7, 2022
Tailoring the analysis of whole genome sequencing to individual patients could double the diagnostic rates of rare diseases, finds a new study led by UCL researchers.
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Scientists sequence Beethoven's genome for clues into his painful past
NPR Health - Shots
MARCH 22, 2023
Scientists have sequenced the genome of Ludwig van Beethoven from two-century-old locks of hair, and found clues about the ailments that plagued him in life. Image credit: Henry Guttmann Collection/Getty Images)
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The future, now: Revolutionising disease prevention through predictive genomics
pharmaphorum
JUNE 30, 2023
The future, now: Revolutionising disease prevention through predictive genomics Mike.Hammerton Fri, 30/06/2023 - 08:00 Bookmark this
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American Urological Association: Genomic urine test accurately predicts bladder cancer
Medical Xpress
MAY 15, 2023
A new genomic urine test can predict bladder cancer as many as 12 years before clinical signs and symptoms emerge, according to a study presented at the annual meeting of the American Urological Association, held from April 28 to May 1 in Chicago.
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Here’s how the $100 Human Genome will Change Medicine
BioSpace
JULY 10, 2022
A silicon wafer offers the powerful insights of the human genome for the low price of $100. Ultima Genomics CEO Gilad Almogy discussed the therapeutic possibilities with BioSpace.
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Kansas children’s hospital first to use world’s most advanced genomic sequencing
BioPharma Reporter
OCTOBER 10, 2023
Childrenâs Mercy Kansas City, an independent pediatric health organization, has become the first health care system to replace old genetic tests, such as rapid exome and chromosomal microarray analysis, with the worldâs most-advanced genomic sequencing technology from PacBio.
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Seqera Labs partners with Genomics England to enhance genomic research capabilities
Drug Discovery Today
MAY 26, 2023
BARCELONA/LONDON, 25.05.23: Seqera Labs, the leading provider of secure workflow orchestration software in the life sciences sector, has partnered with Genomics England, the government-owned company that launched the 100,000 Genomes Project in partnership with the NHS.
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STAT+: Upstart Element ratchets up race for cheaper DNA sequencing with a $200 genome
STAT News
JANUARY 11, 2023
But genomics startup Element Biosciences on Wednesday announced it can now read a whole human genome for as little as $200 — the cost of a couple trips to the grocery store. SAN FRANCISCO — Decoding the billions of chemical letters that help shape who we are once cost a fortune.
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UK genomics market valued at over £5bn, according to new report
Pharma Times
JULY 30, 2021
‘Genomics Nation’ report launched in a bid to showcase the thriving UK genomics sector
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Inclusive new tool makes genomic research better reflect world’s diversity
Scienmag
MARCH 10, 2022
Scientists have developed a powerful, inclusive new tool for genomic research that boosts efforts to develop more precise treatments for many diseases by leveraging a better representation of the genetic diversity of people around the world.
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Oncotype DX: Breast cancer, genomics, and rethinking the oncology paradigm
pharmaphorum
JULY 27, 2023
Oncotype DX: Breast cancer, genomics, and rethinking the oncology paradigm Mike.Hammerton Thu, 27/07/2023 - 08:00 Bookmark this
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Genomic consent: New guideline to help researchers and patients
Medical Xpress
NOVEMBER 14, 2022
How can Canada optimize the impact of human genomic sequencing to increase our understanding of disease? New guidance in Canadian Medical Association Journal (CMAJ) lays out the key elements for obtaining patient consent for researchers and policymakers in this growing field.
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Incidental findings in genomics
Scienmag
JUNE 10, 2022
Vienna, Austria: As the cost of genome and exome1 sequencing falls, its use in characterising rare diseases and personalising cancer treatment, for example, is becoming far more frequent. But such analyses may throw up findings unrelated to the condition for which it has been requested.
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