Remove Bacteria Remove Contamination Remove DNA Remove Manufacturing
article thumbnail

Biopharmaceutical Filtration: A Deep Dive

Roots Analysis

It involves the separation of unwanted particles from biological materials to obtain contaminant free products. Membrane Filters: Membrane filters are typically used for sterilization and removal of smaller impurities such as bacteria and viruses. are used to remove any residual bacteria, viruses, or endotoxins.

article thumbnail

Advances in cell line development

Drug Discovery World

Cell line development is an essential underpinning of the drug development process, enabling teams to test, optimise and manufacture therapeutics at a commercial scale. For instance, bacteria and yeast cell lines are easier to cultivate compared with mammalian cell lines, requiring less maintenance for the medium they are grown in.

article thumbnail

Improving quality control for CAR T cell therapies

Drug Discovery World

And as researchers study all of these factors, they are also discovering that CAR T cell development and manufacturing require a new approach to quality control to ensure their safety and efficacy. The challenge of manufacturing CAR T cells. Developing the first CAR T cell therapy.