Remove Bioassay Remove Containment Remove Development Remove Genomics
article thumbnail

Evaluating methods targeting Protein-Protein Interactions

pharmaphorum

The issue, however, is developing an effective way of targeting them. . Understanding the mechanism of PPIs and developing methods to target aberrant ones has been a key strategy in drug development. The interface is highly hydrophobic, hence any compounds containing water would be repelled.

Protein 125
article thumbnail

Can artificial intelligence help craft new medicines?

Drug Discovery World

The potential of drug targets Over the next 50 years, new targets emerged and drugs were developed against them. Here, new bioassay technologies helped testing, but more definite answers were required. Often drug targets already validated in academic literature are picked up for drug discovery and development efforts.