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Evaluating methods targeting Protein-Protein Interactions

pharmaphorum

AUGUST 5, 2021

Whereas targets like receptors contain an obvious ligand-binding site for drug molecules to interact with, PPIs comprise a more complex structure. The interface is highly hydrophobic, hence any compounds containing water would be repelled. This innovative method now brings technology closer to developing genome-wide PPI networks.

Protein 125
Protein Gene Bioassay DNA 125
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Can artificial intelligence help craft new medicines?

Drug Discovery World

MAY 4, 2023

Here, new bioassay technologies helped testing, but more definite answers were required. Expression patterns, proteomic profiles, bioassay results, and structures could now be captured en masse in normal and disease conditions. The MorCVD database contains all the human proteins that can be potentially involved in heart disease.

Medicine 52
Medicine Protein Drugs Bioassay 52
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