Remove Bioassay Remove Development Remove Genome Remove RNA
article thumbnail

RNA-based immunotherapy eradicates melanoma tumours

Drug Discovery World

Investigators at the Icahn School of Medicine at Mount Sinai have designed an RNA-based strategy to activate dendritic cells that eradicated tumours and prevented their recurrence in mouse models of melanoma. Dendritic cells have been a key focus for the development of new cancer therapies as these cells organise the cancer-immunity cycle.

RNA 52
article thumbnail

Using analytics and bioassays to de-risk your mRNA LNP drug development programme

Pharmaceutical Technology

The swift development and deployment of messenger-RNA (mRNA) vaccines against the SARS-CoV-2 virus during the COVID-19 crisis has catapulted the pharmaceuticals industry into a new paradigm. They can react with RNA and inactivate the RNA itself.” This involves monitoring the material in different conditions.

Bioassay 130