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Accelerating NDA filing through faster carcinogenicity assessment

Drug Discovery World

The International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH) issues guidelines and develops testing strategies for evaluating carcinogenicity along with other risks such as genotoxicity, immunotoxicity, and reproductive toxicity. In practice, this was typically conducted in rats and mice.

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Let's Quit Sugar With Audiobook – Let's Quit Sugar

The Pharma Data

Exposure to sorbitol during lactation causes metabolic alterations and genotoxic effects in rat offspring. The Yale Journal of Biology and Medicine. Preventive Medicine Reports. Experimental & Molecular Medicine. Journal of addiction medicine. Aspartame bioassay findings portend human cancer hazards.

Insulin 52