Genotoxicity Related Topics 
BioTech 365
AUGUST 5, 2020
Number of Tests Accepted per Day is Limited to Ensure Rapid Turnaround Time AUSTIN, Texas–(BUSINESS WIRE)–#coronavirus–Genotox Laboratories, an Austin, Texas based company, has announced the capacity to complete 1,500 COVID-19 tests per day.
BioTech 365
MARCH 10, 2021
Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: PCR-test reveals risk of genotoxity of genome editing. from European Biotechnology – first and foremost in European biotech [link].
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The Pharma Data
MAY 3, 2021
According to a Step 4 training presentation on the guideline, the Q3C (R8) Expert Working Group (EWG) review of available toxicity data with 2-MTHF, also known as tert -butylmethyl ether, found no evidence for genotoxicity or reproductive toxicity and no observed effect level in repeat dose toxicity studies involving rats. For CPME, EWG’s review found no evidence of genotoxicity and no data available demonstrating carcinogenic effects. Posted 03 May 2021 | By Joanne S. Eglovitch .
Camargo
DECEMBER 22, 2021
A nonclinical safety evaluation program typically includes pharmacology, general toxicity, toxicokinetics, nonclinical PK, reproductive toxicity, genotoxicity, and carcinogenesis.
Pharmaceutical Technology
DECEMBER 9, 2022
Dedicated experts in extractables and leachables and genotoxic impurities (GTIs) deploy organic trace analysis by liquid chromatography-mass spectrometry (LC-MS), as well as gas chromatography-mass spectrometry (GC-MS) equipment. Rankings 2022.
Camargo
APRIL 20, 2021
Sponsors can select the patient population and leverage companion diagnostics, and nonclinical study requirements such as genotoxicity and carcinogenicity studies can often be waived or delayed to later stages of development, especially for end-stage cancer therapies.
Pharmaceutical Technology
JUNE 26, 2022
Drug substance plays a key part in ensuring a drug program achieves its major milestones, keeps to budget and delivers on its corporate goals.
CATO Research
NOVEMBER 5, 2020
Based on preliminary data and published reports, exposure to high doses of the genotoxic agent melphalan might render the residual malignant myeloma cells into more aggressive clones, accelerating relapse (8, 9) by potentially altering the stroma (10, 11). Multiple myeloma (MM) is a malignant disease of the bone marrow characterized by clonal expansion of plasma cells (1, 2).
XTalks
MAY 13, 2022
FDA prefers the use of DEREK, a knowledge-based expert system for the qualitative prediction of toxicity, and SARAH, a statistical software to identify potentially toxic chemicals for assessment of genotoxic and sensitization potential.
The Pharma Data
MARCH 25, 2021
IBRANCE may impair fertility in males and has the potential to cause genotoxicity.
The Pharma Data
MARCH 25, 2021
SG contains a genotoxic component and can cause teratogenicity and/or embryo-fetal lethality when administered to a pregnant woman. Gilead Sciences, Inc.
The Pharma Data
FEBRUARY 8, 2021
IBRANCE may impair fertility in males and has the potential to cause genotoxicity. Pfizer Inc. NYSE: PFE) today announced that the U.S. Patent and Trademark Office (USPTO) recently issued a U.S. Patent Term Extension (PTE) certificate for IBRANCE® (palbociclib).
The Pharma Data
APRIL 14, 2021
TRODELVY contains a genotoxic component, SN-38, and targets rapidly dividing cells.
The Pharma Data
APRIL 7, 2021
TRODELVY contains a genotoxic component, SN-38, and targets rapidly dividing cells. Trodelvy Significantly Reduced the Risk of Death by 49% Compared with Single-Agent Chemotherapy in the Phase 3 ASCENT Study –.
The Pharma Data
MAY 13, 2021
Exposure to sorbitol during lactation causes metabolic alterations and genotoxic effects in rat offspring. Product Name: Let's Quit Sugar With Audiobook – Let's Quit Sugar.
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