Biobanking, Gene Expression and In-Vitro - Clinical Research Informer

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Biobanking

Gene Expression

In-Vitro

Alnylam identifies gene to lower abdominal fat and decrease cardiovascular risk

Pharmaceutical Technology

AUGUST 11, 2022

Alnylam Pharmaceuticals and collaborators have identified rare mutations in the INHBE gene that is expressed in the liver, related to a lower waist-to-hip ratio for body mass index (BMI), which is often used as an indicator of abdominal fat and is correlated with the risk of type 2 diabetes (T2D) and coronary heart disease.

Gene

Gene Biobanking Gene Expression In-Vitro

Fibrosis research: Advances and challenges

Drug Discovery World

JANUARY 24, 2024

Fibrocor is on track to complete all IND-enabling work to support IND filing and initiation of clinical trials in 2024. Phase I of the clinical program will dose healthy volunteers with single ascending doses of FIB992 before proceeding to a multiple ascending dose study where the drug is administered for a two-week period.

Research

Research Gene Expression Drugs Development

Alnylam identifies gene to lower abdominal fat and decrease cardiovascular risk

Fibrosis research: Advances and challenges

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