XTalks

FEBRUARY 9, 2023

Leading clinical trials technology platform provider Medable announced a new partnership with Nova Scotia Health Innovation Hub for a two-year pilot study to improve oncology trial access for patients in rural Nova Scotia through Medable’s decentralized clinical trial (DCT) platform.

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Clinical Trials Clinical Trials Trials Clinical Research 98

pharmaphorum

AUGUST 24, 2022

Diversity in clinical trials is a “scientific imperative”, but how can industry bridge the gap between “why” and “how”? Removing barriers to clinical trial participation for underserved groups is an essential part of addressing health inequalities. Clinical trial participation, she went on, was vital.

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Clinical Trials Clinical Trials Trials Drugs 111

STAT News

OCTOBER 13, 2022

Relmada Therapeutics said Thursday that its experimental treatment for depression failed to achieve the primary goals of a large clinical trial, a significant setback for the company’s only medicine in clinical development.

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Clinical Trials Clinical Trials Trials Drugs 105

Outsourcing Pharma

APRIL 27, 2023

Greenphire, a company that finds solutions for companies wanting to run clinical trials has launched a new patient-facing digital platform.

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Clinical Trials Clinical Trials Trials Clinical Development 98

Drug Discovery World

JANUARY 17, 2023

In this latest episode, DDW’s Megan Thomas is in conversation with two experts when it comes to clinical trials. Walz was recently selected in the 2022 PharmaVoice 100 for the company’s innovative work in the space, and speaks about how real world data can help to boost diversity rates in clinical trials.

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Clinical Trials Clinical Trials Trials Drugs 52

pharmaphorum

NOVEMBER 11, 2022

The lack of diversity in clinical trials has been a topic of debate for decades, but was thrust into the spotlight as the impact of the pandemic on poorer, less educated and ethnically diverse populations became even more apparent. The post IQVIA’s report card for clinical trial diversity: must do better appeared first on.

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Clinical Trials Clinical Trials Trials Pharma Companies 97

Drug Discovery World

JANUARY 17, 2023

In this latest episode, DDW’s Megan Thomas is in conversation with two experts when it comes to clinical trials. Walz was recently selected in the 2022 PharmaVoice 100 for the company’s innovative work in the space, and speaks about how real world data can help to boost diversity rates in clinical trials.

Clinical Trials 52

Clinical Trials Clinical Trials Trials Clinical Development 52

XTalks

MAY 11, 2023

Clinical trials are essential for the development of new treatments for rare diseases, but they can be complex and challenging to execute. That mission is really important to me because I think it’s the only way we’re going to accelerate drug development in rare disease.

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Clinical Trials Clinical Trials Trials Drugs 94

Outsourcing Pharma

MAY 31, 2023

Pamela Tenaerts, chief scientific officer at Medable, is on a mission to democratize and diversify clinical trials.

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Clinical Trials Clinical Trials Trials Clinical Development 64

pharmaphorum

JANUARY 14, 2022

In the latest episode of the pharmaphorum podcast, Dr Paul Tunnah speaks to head of Patient Engagement at Syneos Health, Marie Emms, and Elligo executive vice president and general manager of Worldwide Clinical Trials Early Phase Services, Keith Fern. Keith Fern joins Elligo with a decade of proven leadership in the CRO industry.

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Clinical Trials Clinical Trials Trials Clinical Development 98

ACRP blog

DECEMBER 22, 2022

Another important step forward was the core competency framework developed by the Joint Task Force for Clinical Trials Competency (JTF). This covers eight subject domains defining the knowledge, skills, and attitudes necessary for conducting safe, ethical, and high-quality clinical research. “Our Author: Jill Dawson.

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Clinical Trials Clinical Trials Trials Clinical Research 52

pharmaphorum

NOVEMBER 17, 2020

Pharmaceutical companies often struggle to actively involve patients in the design phase of clinical trials but doing so can have huge benefits for the sustainability and success of research. How the NIHR’s Patient Engagement in Clinical Development service can help.

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Clinical Trials Clinical Trials Trials Clinical Research 116

Drug Discovery World

JANUARY 30, 2023

Dominic Elliston , Managing Director of Evoke Galliard and Evoke Incisive Health, shares his take on how effective clinical trial communications is the key to expediting the delivery of new and extraordinary treatments. What’s that got to do with clinical trials? Tell us about yourself, Dominic. The fast-paced variety!

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Clinical Trials Clinical Trials Trials Drugs 52

Pharmaceutical Technology

MAY 26, 2023

NurrOn Pharmaceuticals CEO Deog Joong Kim stated: “NurrOn has completed the preclinical development of ATH-399A and plans to enter a Phase I clinical trial this year. “We The company has recently received funding from the Michael J Fox Foundation to support the Phase I clinical trial of ATH-399A.

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Clinical Trials Clinical Trials Development Protein 130

Pharmaceutical Technology

MAY 17, 2023

Boundless Bio intends to use the funds for the initial clinical development of the first ecDNA-directed therapy (ecDTx), BBI-355, through clinical data readouts from its ongoing Phase I/II POTENTIATE clinical trial. The company is developing the assay with SOPHiA GENETICS.

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Clinical Trials Clinical Trials Genetics Clinical Development 147

XTalks

FEBRUARY 10, 2023

According to a recent review published in Nature , as of April 2022 almost 1,800 active cell therapy clinical trials were listed in ClinicalTrials.gov, a 33 percent increase from 2021. In a recent webinar, Dr. Vassallo discussed the operational considerations for complex cell therapy clinical trials.

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Clinical Trials Clinical Trials Trials Gene Therapy 52

Worldwide Clinical Trials

FEBRUARY 6, 2023

When using genetic screening to identify clinical trial volunteers, a sponsor’s obligations for further testing and disclosure of results to patients and families are unclear, especially when the results have no impact on medical management. Guidance in this area is much needed. Read the full article!

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Genetics Clinical Trials Clinical Trials Genotype 130

Outsourcing Pharma

OCTOBER 18, 2022

Walmart joins rival retailers by launching its service for clinical trial recruitment, stating that it will focus on older, rural, women and minority populations.

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Clinical Trials Clinical Trials Trials Clinical Development 98

pharmaphorum

MAY 27, 2021

Sheila Rocchio highlights four key areas life sciences must improve on as an industry to drive real change in how clinical trials are conducted. Access to finding the right patients to participate in trials is often cited as the number one obstacle for completing a clinical trial on time and within budget.

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Clinical Trials Clinical Trials Trials Life Science 119

XTalks

OCTOBER 12, 2022

Magnetic resonance imaging (MRI) has had a part in clinical trials for more than three decades now. However, the role of MRI in new drug clinical trials can involve diagnosis of lesions and determination of their severity, early identification of therapeutic responders to drug treatment and treatment monitoring and follow-up.

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Clinical Trials Clinical Trials Trials Drugs 85

pharmaphorum

MARCH 24, 2021

Pfizer has begun clinical development of an antiviral pill against COVID-19, which could be prescribed to patients at the first sign of infection. The post Pfizer begins clinical trials of COVID-19 antiviral pill appeared first on. ” Feature image courtesy of Rocky Mountain Laboratories/NIH.

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Clinical Trials Clinical Trials Trials Vaccination 119

Pharmaceutical Technology

MAY 31, 2023

Setanaxib is under clinical development by Calliditas Therapeutics and currently in Phase III for Primary Biliary Cholangitis (Primary Biliary Cirrhosis). GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data.

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Clinical Trials Clinical Trials Drugs Clinical Development 100

XTalks

NOVEMBER 19, 2021

Cardiac biomarkers can not only serve important roles in the diagnosis, management and prognosis of cardiac diseases, but they can also be significant tools in evaluating treatments in cardiovascular (CV) clinical trials. In CV clinical trials, cardiac biomarkers are most commonly included in efficacy and safety endpoints.

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Clinical Trials Clinical Trials Trials Drugs 98

Outsourcing Pharma

MARCH 20, 2023

Despite diversity being spoken about more than ever before, research discovers clinical trials are less representative of the US population compared to a decade prior.

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Clinical Trials Clinical Trials Trials Research 64

Pharmaceutical Technology

JUNE 2, 2023

EDDING clinical development vice-president Rebecca Xu said: “In November 2020, EDDING announced the positive, statistically significant top-line results of the Phase III clinical trial conducted in Mainland China in severe hypertriglyceridemia patients.”

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Clinical Trials Clinical Trials Clinical Development Drugs 130

pharmaphorum

SEPTEMBER 4, 2020

Sanofi and GlaxoSmithKline have begun clinical trials of their coronavirus vaccine, as AstraZeneca expanded studies of its rival into Japan. If trials go well the companies could request regulatory approval in the first half of 2021. Sanofi is leading the clinical development and registration of the COVID-19 vaccine.

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Clinical Trials Clinical Trials Vaccination Vaccine 106

XTalks

MAY 6, 2022

In this interview, Xtalks spoke with experts from eClinical Solutions , Katrina Rice, Chief Delivery Officer, Data Services; and Diane Lacroix, Vice President, Clinical Data Management, about clinical data management for modern day digital clinical trials. Data security: The clinical trial data is backed-up and secure.

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Clinical Trials Clinical Trials Trials Life Science 98

Drug Discovery World

OCTOBER 18, 2022

A working group has been created to measure and compare the carbon footprint of centralised (traditional site-based) and decentralised clinical trials. The Clinical Trials Environmental Impact Community of Interest (CoI) was started by Pistoia Alliance member, Syneos Health. Growing pressure on life sciences.

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Clinical Trials Clinical Trials Trials Pharma Companies 52

Pharmaceutical Technology

FEBRUARY 8, 2023

On February 7, at a town hall organised to discuss clinical trial designs for gene therapies, FDA experts pushed pharma players to look for ways to establish clinical effectiveness despite the challenges in recruiting patients with rare diseases. GlobalData is the parent company of Pharmaceutical Technology.

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Gene Therapy Gene Trials Clinical Trials 264

Outsourcing Pharma

NOVEMBER 9, 2022

Clinical trial participants are traveling further to attend study sites than previously thought, according to Greenphireâs analysis of its payment data.

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Clinical Trials Clinical Trials Trials Clinical Development 97

Outsourcing Pharma

SEPTEMBER 13, 2022

Bayer Pharma has enlisted Clariness to support its new study review process by providing pre-clinical trial patient insights and post-trial feedback.

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Clinical Trials Clinical Trials Trials Clinical Development 98

Pharmaceutical Technology

MAY 2, 2023

This will help to meet the rising demand for Plus Therapeutics’ lead investigational targeted radiotherapeutic, rhenium (186Re) obisbemeda, for clinical trials that are underway and planned.

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Drugs Clinical Trials Clinical Trials Production 130

Pharmaceutical Technology

MAY 2, 2023

Pamrevlumab, a human monoclonal antibody targeting connective tissue growth factor, is currently undergoing clinical trials for the treatment of conditions including idiopathic pulmonary fibrosis, locally advanced unresectable pancreatic cancer, metastatic pancreatic cancer and Duchenne muscular dystrophy.

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Clinical Trials Clinical Trials Antibody Clinical Development 130

pharmaphorum

JUNE 9, 2022

Owkin has enticed another big pharma partner with its artificial intelligence-powered clinical development platform, Bristol-Myers Squibb, which is paying $80 million upfront to tap into its expertise. The companies say they also aim to improve clinical trial outcomes with covariate adjustment, using real-world data.

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Clinical Trials Clinical Trials Trials Clinical Development 59

Drug Discovery World

DECEMBER 7, 2022

A new report reveals steadily growing interest in the clinical applications of collagen over the last 10 years. . Data analytics company Phesi analysed 2,358 clinical trials involving collagen. In the first 10 months of 2022, there were more than 225 new trials, compared with 125 in 2012.

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Clinical Trials Clinical Trials Trials Clinical Research 52

Pharmaceutical Technology

FEBRUARY 10, 2023

Tech-enabled, next-generation contract research organisation (CRO) Vial has announced a partnership to integrate Egnyte’s Life Sciences electronic trial master file (eTMF) solution into its clinical trial platform. We’re thrilled to be able to constantly increase the bar in clinical trial technology.”

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Clinical Trials Clinical Trials Life Science Clinical Development 130

Pfizer

FEBRUARY 16, 2023

These study participants, representing approximately half of the total recruited participants in the trial, are being discontinued following violations of Good Clinical Practice (GCP) at certain clinical trial sites run by a third-party clinical trial site operator.

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Clinical Trials Clinical Trials Vaccination Vaccine 76