Pharmaceutical Technology

APRIL 27, 2023

Genomic medicine development was ranked as the top industry trend for 2023 in a survey of 198 GlobalData Pharma clients and prospects conducted between October and November 2022. GlobalData pharmaceutical analysts project that RNA-based gene therapies for oncology will grow from zero in 2022 to $4.6 billion by 2028.

Manufacturing 130

Manufacturing RNA Contamination Vaccination 130

Drug Discovery World

FEBRUARY 28, 2023

In addition, the purity of the final product can be evaluated by using ultrasensitive digital PCR, to detect any residual non-mRNA products, and 16S sequencing, to identify bacterial contamination. The structure of the mRNA is of key importance as it influences the translation efficiency and stability of the transcript in the cell.

Genetics 52

Genetics Genetic Analysis Vaccination Vaccine 52

Drug Discovery World

AUGUST 10, 2022

If the gene does not integrate into the genome, the cell will not become a CAR T cell. Furthermore, even if the transgene enters the cell in the correct numbers, the location where the gene integrates into the genome is somewhat random. The gene could also bury itself in a silenced region of the genome, leaving the gene dormant.

Manufacturing 98

Manufacturing Gene Genome Genomics 98

XTalks

NOVEMBER 7, 2022

These tumor-derived entities are used to derive genomic and proteomic data. However, Dr. Bahassi reported that the selection of CTCs using this method is often not very efficient and the CTC population is usually highly contaminated with leukocytes. Detection of Genomic Alterations from cfDNA: Targeted, Non-Personalized Approaches.

Clinical Trials 98

Clinical Trials Clinical Trials Trials FDA Approval 98