article thumbnail

Five key drug discovery deals of summer 2023

Drug Discovery World

The news followed an announcement that Biogen would be cutting around 1,000 jobs, or 11% of its workforce, to allow investment into its product pipeline. We are very excited to continue the development of sepofarsen and ultevursen for patients,” said Jean-Frédéric Chibret, President of the Théa group.

Drugs 52
article thumbnail

The Power of Lipids: Enhancing Drug Delivery with Nanoparticles

Roots Analysis

SLNs offer various benefits, such as easy production process, good release profile and low cost. However, their drawbacks include limited drug loading capacity and potential drug expulsion during storage. The LNPs can be monitored using various imaging modalities to confirm the delivery of siRNA to the target cells.

Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

mRNA Synthesis: ManufacturingProcess of Modern Revolutionary Molecule

Roots Analysis

The production of such drug products requires skilled labor, stringent manufacturing protocols and specialized expertise. Additionally, they also require appropriate drug delivery systems to efficiently administer the intervention (in a manner that they can avoid degradation by cellular endonucleases).

article thumbnail

Growing Demand for Oligonucleotides Proposes Shedload of Opportunities for Contract Manufacturers

Roots Analysis

In the 20 th century, major research went into discovery of a therapeutic class with the primary purpose of interfering with the RNA expression linked to disease causing proteins, nowadays classified as oligonucleotides. Oligonucleotide Synthesis, Modification and Purification Services Market. Our Social Media Platform. Web: [link].

article thumbnail

Considerations for Neuroscience Trials with Intrathecal Delivery and Other Methods of Direct CNS Administration

XTalks

According to an analysis of the 2013 Medical Expenditure Panel Survey, one in six US adults reported taking a psychiatric drug at least once in 2013. Global sales of over-the-counter and prescription products related to central nervous system (CNS) disease added up to $86 billion in 2019.

Trials 83
article thumbnail

Covid-19 vaccine success bolsters nanoparticle drug delivery research

Pharmaceutical Technology

Since then, the field of nanomedicine has steadily progressed to reach high points such as the successful use of nanotechnology to deliver messenger RNA (mRNA)-based Covid-19 vaccines. Due to their size, cells can absorb them where they release products. Langer, now a David H.