Sun.Aug 20, 2023

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Scientists Identify a Hidden Pattern of Consciousness in The Brains of Coma Patients

AuroBlog - Aurous Healthcare Clinical Trials blog

Scientists have used advanced imaging techniques to identify brain activity and regions linked to cognitive motor dissociation (CMD), or ‘hidden consciousness‘ CMD is a state in which a person appears comatose and unresponsive while inwardly showing signs of conscious brain activity.

Scientist 203
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CRISPR Shows Preclinical Promise in Treating Alzheimer’s as Challenges Persist

BioSpace

At AAIC, researchers presented studies using CRISPR-Cas9 in animal/organoid models of Alzheimer’s disease, but some experts doubt that such approaches will successfully translate to humans.

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NABL follows rigorous process while giving accreditation to a drug testing laboratory: NABL CEO

AuroBlog - Aurous Healthcare Clinical Trials blog

The National Accreditation Board for Testing and Calibration Laboratories (NABL) follows a rigorous process while giving accreditation to a drug testing laboratory. It includes the scrutiny of application as well as quality management system (QMS) documents in accordance with ISO/IEC 17025:2017, informs N Venkateswaran, CEO, NABL.

Drugs 131
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Roche, Exelixis’ Drug Combo Bounces Back with Late-Stage Prostate Cancer Win

BioSpace

After sustaining two Phase III fails, Roche and Exelixis finally reported a late-stage win for their combination regimen of Tecentriq and Cabometyx in metastatic castration-resistant prostate cancer.

Drugs 76
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European Clinical Supply Planning: Balancing Cost, Flexibility and Time

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Late Mortality After COVID-19 Infection in Veterans vs Risk-Matched Comparators

JAMA Internal Medicine

This retrospective cohort study of COVID-19 survivors and matched uninfected comparators assesses the time course of excess mortality after COVID-19.

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Regeneron Expands Eylea’s Label with High-Dose Approval

BioSpace

Following a prior rejection due to manufacturing problems, Regeneron’s higher-dose Eylea won the FDA’s approval Friday, allowing for more infrequent dosing for the treatment of various eye diseases.

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Moderna, CARsgen Join Forces Combining mRNA Cancer Vaccine with CAR T

BioSpace

The companies will evaluate Moderna’s investigational Claudin18.2 mRNA cancer vaccine in combination with CARsgen’s Claudin18.2 CAR T cell candidate.

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Novel Spectrometry Platforms: Key Advancements

Roots Analysis

Spectrometry is an analytical technique that is used to analyze the fundamental components of a radiation or ion beam’s spectrum. There are two main divisions of spectrometry, which involve the use of electromagnetic radiation and ionization ( also known as mass spectrometry ), respectively. The former division of spectrometry uses electromagnetic radiation from different regions of an electromagnetic spectrum as the source of energy whereas the latter uses high energy electrons as its energy so

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FDA Pilot Program for Cancer Diagnostics Met with Skepticism

BioSpace

Some experts question the value of recently issued FDA guidance that aims to address gaps in the quality of unapproved laboratory tests for cancer.

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Changes in the Use of Long-Term Medications Following Incident Dementia Diagnosis

JAMA Internal Medicine

This cohort study investigates changes in use of common medications after an incident dementia diagnosis in a national sample of Medicare beneficiaries.

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The New Age of Decentralized Clinical Trials

White paper that delves into the complex topic of Decentralized Clinical Trials and how to master them within the confines of FDA Regulations

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Addressing the UK’s Scientific Skills Gap

BioSpace

If we want to make the UK a scientific superpower, we need to address the elephant in the room: the skills gap.

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Regeneron gets FDA blessing for CHAPLE drug Veopoz

pharmaphorum

Regeneron gets FDA blessing for CHAPLE drug Veopoz Phil.

Drugs 83
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Gilead’s Magrolimab Again Placed on Partial Clinical Hold by FDA

BioSpace

The biopharma’s acute myeloid leukemia hopeful is on partial clinical hold, affecting two Phase III AML studies, Gilead announced Monday. The CD47 candidate also spent four months on hold in 2022.

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Which pharmaceutical companies have the most drug patents in Eurasian Patent Organization?

Drug Patent Watch

This chart shows the pharmaceutical companies with the most patents in Eurasian Patent Organization. Patents must be filed in each country (or, in some cases regional patent office) where patent… The post Which pharmaceutical companies have the most drug patents in Eurasian Patent Organization? appeared first on DrugPatentWatch - Make Better Decisions.

Drugs 40
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Unlocking Excellence: How Catalent Is Transforming Japan’s Clinical Research

Planning on running clinical trials in Japan? How can you reliably supply these studies? Discover Catalent’s clinical supply packaging facility in Shiga, Japan. Strategically located between Tokyo and Osaka, and one of largest in Japan, this 6,000 square meter facility offers comprehensive services including primary and secondary clinical packaging and labelling, comparator sourcing, cold chain storage, local and global distribution, local language support and white glove service to support stud