Sat.May 13, 2023

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Binge eating linked to habit circuitry in the brain

Medical Xpress

Habits are like shortcuts for our brains. Once we form a habit—say, putting on a seat belt whenever we get into a car—the behavior becomes almost automatic in the right context. But habit formation isn't always a boon. The same neural circuitry that helps us to buckle up underlies binge eating disorders, according to a new study by Stanford Medicine researchers and collaborators.

Medicine 130
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New patent expiration for Eisai Inc drug BANZEL

Drug Patent Watch

Annual Drug Patent Expirations for BANZEL Banzel is a drug marketed by Eisai Inc and is included in two NDAs. It is available from one supplier. There is one patent… The post New patent expiration for Eisai Inc drug BANZEL appeared first on DrugPatentWatch - Make Better Decisions.

Drugs 98
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Restoring control to a particular brain region may help to prevent return to use of opioids

Medical Xpress

A team of neuroscientists at the Medical University of South Carolina (MUSC) has identified changes in the activity of brain cells known as pyramidal neurons, which contribute to drug seeking in a preclinical model of opioid use disorder. After access to heroin was stopped, these neurons became more excitable. The activity of these neurons was restored to normal by blocking the enzyme protein kinase A (PKA).

Protein 111
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Optimizing Clinical Trial Management: The Role of Site Monitoring Metrics and KPIs

Cloudbyz

Overview: Clinical site monitoring metrics and Key Performance Indicators (KPIs) are fundamental tools in the realm of clinical trial management. They provide a way to quantify and evaluate critical aspects of a clinical trial’s performance at individual investigative sites. The range of these metrics is vast, encompassing areas like patient recruitment and retention, data quality, protocol adherence, safety reporting, and much more.

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European Clinical Supply Planning: Balancing Cost, Flexibility and Time

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Both metabolically healthy and unhealthy forms of obesity found to increase risk of obesity-related cancers

Medical Xpress

New research to be presented at this coming week's European Congress on Obesity in Dublin, Ireland (May 17–20) and published in the Journal of the National Cancer Institute shows that both the metabolically healthy and unhealthy 'forms' of obesity are associated with an increased risk of various obesity-related cancers, with the relationship stronger in metabolically unhealthy obesity.

Research 103
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DIA 2023 Annual Global Meeting

CTTI (Clinical Trials Transformation Initiative)

Presentation: Meta-Collaboration to Improve Decentralized Trials Date: Tues., June 27, 1:15 – 2:15 p.m. Presenters: Sara Calvert (CTTI), Robert DiCicco (TransCelerate), Susan Landis (ACRP), and Jane Myles (Curebase) The post DIA 2023 Annual Global Meeting appeared first on CTTI.

Trials 40
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Unlocking Clinical Trial Success: Essential KPIs to Monitor in a Clinical Trial Management System (CTMS)

Cloudbyz

Overview: This comprehensive guide delves into the critical role of Key Performance Indicators (KPIs) in the context of a Clinical Trial Management System (CTMS). As the biotechnological and pharmaceutical industries increasingly rely on these software systems, understanding the breadth of KPIs that a CTMS can generate is key. From enrollment progress and trial timelines to safety metrics, budget tracking, and patient satisfaction, these systems offer a centralized hub to effectively manage the