Mon.Dec 26, 2022

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LegoChem, Amgen partner to develop antibody drug conjugates

Pharmaceutical Technology

LegoChem Biosciences and Amgen have signed a multi-target research collaboration and license agreement to develop antibody-drug conjugates (ADC). Under the deal terms, Amgen was granted rights for the research, development, and commercialisation of ADCs that will be directed to treat up to five targets which are chosen by the company using the ConjuAll ADC technology of LegoChem.

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I usually wake up just ahead of my alarm. What's up with that?

NPR Health - Shots

Call it "precision waking" — the alleged ability to decide when you want to wake up and then doing so, without an alarm. If you think you can do it, you're not alone, though how is still mysterious.

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Females on average perform better than males on a 'theory of mind' test across 57 countries

Medical Xpress

Females, on average, are better than males at putting themselves in others' shoes and imagining what the other person is thinking or feeling, suggests a new study of over 300,000 people in 57 countries.

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New patent expiration for Novo Nordisk drug VICTOZA

Drug Patent Watch

Annual Drug Patent Expirations for VICTOZA Victoza is a drug marketed by Novo Nordisk Inc and is included in one NDA. It is available from two suppliers. There are seven…. The post New patent expiration for Novo Nordisk drug VICTOZA appeared first on DrugPatentWatch - Make Better Decisions.

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Unlocking Excellence: How Catalent Is Transforming Japan’s Clinical Research

Planning on running clinical trials in Japan? How can you reliably supply these studies? Discover Catalent’s clinical supply packaging facility in Shiga, Japan. Strategically located between Tokyo and Osaka, and one of largest in Japan, this 6,000 square meter facility offers comprehensive services including primary and secondary clinical packaging and labelling, comparator sourcing, cold chain storage, local and global distribution, local language support and white glove service to support stud

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Oral anticoagulants found to be more effective and cost-effective than heparin for cancer-associated thrombosis

Medical Xpress

A cost-effectiveness analysis comparing direct oral anticoagulants (DOACs) to low-molecular-weight heparin (LMWH) found that DOACs are both more medically effective and cost-effective than LMWH when treating cancer-associated thrombosis (CAT). These findings may inform decisions on the clinical level as well as policy decisions. The analysis is published in Annals of Internal Medicine.

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China will end its COVID-19 quarantine requirement for incoming passengers

NPR Health - Shots

The scrapping of the quarantine requirement starting Jan. 8 is a major step toward reopening travel with the rest of the world, which the government severely curtailed in a bid to keep the virus out.

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Effect of COVID-19 Vaccine Messaging Platforms in Emergency Departments on Vaccine Acceptance and Uptake

JAMA Internal Medicine

This cluster randomized clinical trial aims to determine whether provision of COVID-19 vaccine messaging platforms in emergency departments increases COVID-19 vaccine acceptance and uptake in unvaccinated patients.

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China races to vaccinate elderly, but many are reluctant

Medical Xpress

Chinese authorities are going door to door and paying people older than 60 to get vaccinated against COVID-19. But even as cases surge, 64-year-old Li Liansheng said his friends are alarmed by stories of fevers, blood clots and other side effects.

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New tentative approval for Teva Pharms drug eltrombopag

Drug Patent Watch

[![eltrombopag structure]([link] Eltrombopag is the generic ingredient in two branded drugs marketed by Novartis and is included in two NDAs. There are eight patents protecting this compound. There are four…. The post New tentative approval for Teva Pharms drug eltrombopag appeared first on DrugPatentWatch - Make Better Decisions.

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Xi urges steps to 'protect' lives as China battles Covid wave

Medical Xpress

Chinese President Xi Jinping urged officials on Monday to take steps to protect lives in his first public remarks on COVID-19 since Beijing dramatically loosened hardline containment measures this month.

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The New Age of Decentralized Clinical Trials

White paper that delves into the complex topic of Decentralized Clinical Trials and how to master them within the confines of FDA Regulations

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New tentative approval for Amneal Pharms drug saxagliptin

Drug Patent Watch

[![saxagliptin structure]([link] Saxagliptin is the generic ingredient in one branded drug marketed by Astrazeneca Ab and is included in one NDA. There are two patents protecting this compound. There are…. The post New tentative approval for Amneal Pharms drug saxagliptin appeared first on DrugPatentWatch - Make Better Decisions.

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Long COVID: Could mono virus or fat cells be playing roles?

Medical Xpress

A British historian, an Italian archaeologist and an American preschool teacher have never met in person, but they share a prominent pandemic bond.

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Drug Patent Expirations for the Week of December 25, 2022

Drug Patent Watch

VICTOZA (liraglutide recombinant) Novo nordisk inc Patent: 8,846,618 Expiration: Dec 27, 2022 See More … For more information on how DrugPatentWatch can help with your pharmaceutical business intelligence needs, contact…. The post Drug Patent Expirations for the Week of December 25, 2022 appeared first on DrugPatentWatch - Make Better Decisions.

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Spontaneous baby movements are important for development of coordinated sensorimotor system

Medical Xpress

Spontaneous, random baby movements aid development of their sensorimotor system, according to new research led by the University of Tokyo. Detailed motion capture of newborns and infants was combined with a musculoskeletal computer model to enable researchers to analyze communication among muscles and sensation across the whole body.

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Roles and Responsibilities of Specialized Clinical Supply Experts

When selecting a clinical supply provider, consideration often focuses upon the manufacturing, packaging, storage and distribution capabilities available that will, at face-value, be sufficient to meet the needs of the sponsor and their trial. However, there are human-based and knowledge-driven factors that are often overlooked that go beyond these basic physical capabilities and are integral to the development and delivery of high performing clinical supply chains.

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New patent expiration for NOVO drug SAXENDA

Drug Patent Watch

Annual Drug Patent Expirations for SAXENDA Saxenda is a drug marketed by Novo and is included in one NDA. It is available from two suppliers. There are twenty-five patents protecting…. The post New patent expiration for NOVO drug SAXENDA appeared first on DrugPatentWatch - Make Better Decisions.

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Winter is tough on your skin—fight back

Medical Xpress

The key to keeping skin soft in winter: Moisturize.

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Relief Therapeutics Files Amendment No. 2 to its Registration Statement on Form F-1 with the U.S. Securities and Exchange Commission RELIEF THERAPEUTICS Holding SA, announced that it has filed Amendment No. 2 to its Registration Statement on Form F-1 under the Securities Act of 1933 with the U.S. Securities and Exchange Commission relating to a proposed offering of its ordinary shares in the form of American Depositary Shares. NANOBIOTIX Announces First Patient Randomized in the United States in Global Phase 3 Pivotal Trial Evaluating Radioenhancer NBTXR3 in Head and Neck Cancer NANOBIOTIX announced the first patient in the United States has been randomized in NANORAY-312, a global Phase 3 registrational trial evaluating NBTXR3 for the treatment of elderly patients with locally advanced head and neck squamous cell carcinoma who are ineligible for platinum-based chemotherapy. Harm Reduction Therapeutics' New Drug Application for RiVive™ Over-the-Counter Naloxone Nasal Spray Accepted and Granted Priority Review

BioSpace

Mergers and acquisitions are expected to be a key theme in the pharmaceutical industry in 2023.

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Which pharmaceutical companies have the most emulsion dosed drugs?

Drug Patent Watch

This chart shows the pharmaceutical companies with the most emulsion dosed drugs. For a different perspective, see the most popular dosage types. The companies with the most emulsion dosed drugs…. The post Which pharmaceutical companies have the most emulsion dosed drugs? appeared first on DrugPatentWatch - Make Better Decisions.

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The New Age of Decentralized Clinical Trials

This new white paper defines and details the impact of Decentralized Clinical Trials on the Pharmaceutical industry and how the impact can be measured along with steps companies can take to ensure adoption.

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Imaging Drug Cytalux (pafolacianine) Approved for Detection of Lung Cancer During Surgery

XTalks

On Target Laboratories, Inc. has obtained US Food and Drug Administration (FDA) approval of an expanded indication for the use of Cytalux (pafolacianine) for the detection of lung cancer during surgery. This biotech company discovers and develops targeted intraoperative molecular imaging agents to illuminate cancer during surgery. In November 2021, Cytalux received FDA approval to assists surgeons in visually identifying additional malignant tissue in ovarian cancer to be removed during the oper

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Business ecosystems in asset finance: Greater than the sum of their parts

Pharmaceutical Technology

The once cut-throat business landscape is evolving, and business ecosystems are on the rise. Open APIs are facilitating unprecedented collaboration, enabling businesses to pool their resources and expertise to develop better solutions for end users. The opportunities for new innovations and functionalities are enormous. “Companies have long looked at collaboration to increase value, but the idea of expanding such partnerships on a technical basis was enabled by the rise of the internet and linke