Thu.Jun 30, 2022

Blueprint secures access to more than $1B in funding through two new deals

Bio Pharma Dive

Amid a historic market downturn, the precision drug company is raising money through royalty financings with Sixth Street and Royalty Pharma

Pfizer, BioNTech enter $3.2bn deal with US government for Covid-19 shots

Pharmaceutical Technology

Pfizer and BioNTech have entered a new vaccine supply agreement worth $3.2bn with the US government to supply further doses of their Covid-19 vaccine. As per the agreement, the government will procure 105 million 3µg, 10 µg and 30 µg doses of the vaccine.

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Pfizer seeks full FDA approval of Paxlovid as questions about its benefits grow

Bio Pharma Dive

Converting Paxlovid’s emergency authorization to a standard clearance could further broaden its use. But the drug may not meaningfully help people who are vaccinated, and concerns about its potency against emerging variants are growing

Study reveals an unprecedented change in Europe’s fire regime

Scienmag

A study reveals an unprecedented change in the fire regime in Europe which is related to climate change. The affected areas are in Southern, Central and Northern Europe but this historical change in Europe’s fire regime is more intense in the Mediterranean area.

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2022 Research: The Rapid Rise of Ocean Freight Visibility

Download this a benchmark study from FourKites and The Journal of Commerce exploring how international shippers’ usage of global supply chain visibility technology has evolved since the onset of global disruptions caused by COVID-19.

US pays Pfizer $3.2B to increase vaccine supply ahead of omicron booster push

Bio Pharma Dive

The order will bolster the government stockpile of COVID-19 vaccines ahead of a booster rollout that the FDA now says should include shots tailored to the newest versions of omicron

Study shows HIV speeds up body’s aging processes soon after infection

Scienmag

HIV has an “early and substantial” impact on aging in infected people, accelerating biological changes in the body associated with normal aging within just two to three years of infection, according to a study by UCLA researchers and colleagues.

More Trending

Laser creates a miniature magnetosphere

Scienmag

Osaka, Japan – Magnetic reconnections in laser-produced plasmas have been studied to understand the microscopic electron dynamics, which is applicable to space and astrophysical phenomena.

AstraZeneca, chasing immunotherapy rivals, claims study success in early lung cancer

Bio Pharma Dive

A regimen involving its drug Imfinzi improved tumor responses when given before surgery, building on evidence that immunotherapies, already mainstays for advanced disease, could become standard treatments earlier

Drugs 182

Aging-US | Time makes histone H3 modifications drift in mouse liver

Scienmag

BUFFALO, NY- June 30, 2022 – A new research paper was published in Aging (Aging-US) on the cover of Volume 14, Issue 12, entitled, “Time makes histone H3 modifications drift in mouse liver.” Credit: Hillje et al.

FDA halts tests of Sanofi drug, acquired in $3.7B buyout, due to side effects

Bio Pharma Dive

Liver problems in trial volunteers led the agency to curtail studies of the drug, marking the second major setback related to Sanofi’s acquisition of Principia Biopharma

Trials 164

An Innovative & Creative Problem Solver Approach to Selling in the Medical Device Space

Speaker: Steve Goldstein, Sales Leader

Currently in sales or involved in a business that depends on strong sales results? Join Steve Goldstein, Sales Success Coach, Motivational Speaker and Medical Device Sales Leader from Gold Selling LLC. You will absorb critical strategies to become a trusted partner in greater sales success.

Research reveals structure of a human endogenous reverse transcriptase

Scienmag

The crystal structure of a human endogenous reverse transcriptase has similarities to HIV reverse transcriptase, a well-known tractable drug target, which will help design drugs to treat cancer and other diseases, according to a study co-authored by a Rutgers researcher.

Drugs 76

Merck launches accelerator programme for AI startups

pharmaphorum

Merck & Co is looking for startup companies applying artificial intelligence , machine-learning and other digital approaches to drug discovery and development for a new accelerator programme.

Scientists unravel the key to colon cancer relapse after chemotherapy

Scienmag

Approximately 1 in 25 people will develop colon cancer during their lifetime and nearly 2 million cases new cases are diagnosed worldwide each year. Chemotherapy is commonly used to treat colon cancer. While this treatment is initially effective in most cases, many patients relapse after treatment.

Does Plan B Have a Weight Limit?

NY Times

Researchers have looked into why and how weight influences emergency contraception but have come up against several unknowns. Here’s what we know.

Drugs 70

Mandatory COVID Vaccination Policy Template

The federal government is developing a rule requiring employers with more than 100 employees ensure their workers are vaccinated or produce a negative COVID test weekly before entering the workplace. So, what can your organization do to prepare? Get Paycor’s COVID Vaccination Policy Template to help communicate important details to your employees.

Gemini North spies ultra-faint fossil galaxy discovered on outskirts of Andromeda

Scienmag

An unusual ultra-faint dwarf galaxy has been discovered on the outer fringes of the Andromeda Galaxy thanks to the sharp eyes of an amateur astronomer examining archival data processed by NSF’s NOIRLab’s Community Science and Data Center.

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FDA rejection of Spero’s tebipenem ‘raises resistance threat’

pharmaphorum

The FDA’s decision not to approve Spero Therapeutics’ oral antibiotic tebipenem Hbr for adults with complicated urinary tract infections (cUTI) further increases the threat of antibiotic resistance, according to a GlobalData analyst.

Drugs 97

In brief: Surgery may be avoided for children with rare skull tumor

Scienmag

FDA recommends Pfizer, Moderna update their COVID boosters to target omicron subvariants

Fierce Pharma

FDA recommends Pfizer, Moderna update their COVID boosters to target omicron subvariants. zbecker. Thu, 06/30/2022 - 14:49

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Development of ultra-thin, high-efficiency piezoelectric elements that generate electricity from movements in daily life

Scienmag

research team led by Professor Lee Sung-won of the Department of Physics and Chemistry at DGIST (President: Kuk Yang) succeeded in efficiently obtaining electrical energy from small movements of the human body, such as the blink of an eye, by using biocompatible materials to minimize the device’s thickness.

Neglected tropical diseases: non-profits lead the way as private sectors lags

Pharmaceutical Technology

Stagnating interest from private players and added pressure due to the Covid-19 pandemic has put the onus on academia and non-profits to drive new therapies for neglected tropical diseases (NTDs).

Patients with severe brachial plexus injuries who undergo amputation report benefits, Mayo study finds

Scienmag

ROCHESTER, Minn. Reconstruction surgery may not work for some people with severe brachial plexus injuries, so they choose to undergo amputation.

Pfizer's latest $3.2B pandemic vaccine contract suggests private market still a ways off: analysts

Fierce Pharma

Pfizer's latest $3.2B pandemic vaccine contract suggests private market still a ways off: analysts. fkansteiner. Thu, 06/30/2022 - 09:17

Birds warned of food shortages by neighbor birds change physiology and behavior to prepare

Scienmag

CORVALLIS, Ore. Songbirds learning from nearby birds that food supplies might be growing short respond by changing their physiology as well as their behavior, research by the Oregon State University College of Science shows. Credit: Provided by Jamie Cornelius, Oregon State CORVALLIS, Ore.

AstraZeneca's Imfinzi posts positive interim results in pre-surgery lung cancer

Fierce Pharma

AstraZeneca's Imfinzi posts positive interim results in pre-surgery lung cancer. zbecker. Thu, 06/30/2022 - 10:26

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The formation process of unstable unknown radical states visualized clearly for the first time!

Scienmag

? DGIST (President: Kuk Yang) announced on the 26th that Professor Park Jin-hee’s team at the Department of Physics and Chemistry generated new metal-organic frameworks (MOFs) and successfully visualized unstable radical states and identified electron transfer paths according to energy types through structural analysis. Credit: ?

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New patent expiration for Eisai Inc drug LUSEDRA

Drug Patent Watch

Annual Drug Patent Expirations for LUSEDRA Lusedra is a drug marketed by Eisai Inc and is included in one NDA. There is one patent protecting this drug. This drug has…. The post New patent expiration for Eisai Inc drug LUSEDRA appeared first on DrugPatentWatch - Make Better Decisions.

Capturing the onset of galaxy rotation in the early universe

Scienmag

As telescopes have become more advanced and powerful, astronomers have been able to detect more and more distant galaxies. These are some of the earliest galaxies to form in our universe that began to recede away from us as the universe expanded.

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Fibrillar Collagen Wound Dressing by Collagen Matrix Secures the Company Its 40th FDA 510(k) Clearance

XTalks

Collagen Matrix Inc. received its 40 th FDA 510(k) Clearance and this time it was for its Fibrillar Collagen Wound Dressing. The photo shown is one of the company’s products, TruSource™ medical grade collagen. Photo courtesy of Collagen Matrix Inc.

When medicine is not enough for schizophrenia and psychosis

Scienmag

The Brain & Behavior Research Foundation (BBRF) is hosting a free webinar, “When Medicine is Not Enough for Schizophrenia and Psychosis” on Tuesday, July 12, 2022, at 2:00 pm EDT. The presenter will be Dawn I. Velligan, Ph.D.,

Pfizer claims new $3.2bn COVID jab deal with US government

pharmaphorum

Pfizer and BioNTech have signed a new $3.2 billion supply contract with the US government for COVID-19 vaccines, covering 105 million doses that may include Omicron-targeted shots.

Novel gene for Alzheimer’s disease in women identified

Scienmag

(Boston)—Alzheimer’s disease (AD) is a progressive neurodegenerative disorder and the most common cause of dementia, affecting more than 5.8 million individuals in the U.S.

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'The Top Line' podcast: FDA's coming COVID shot makeover, what's driving new M&A activity, plus this week's headlines

Fierce Pharma

The Top Line' podcast: FDA's coming COVID shot makeover, what's driving new M&A activity, plus this week's headlines. tcarey. Thu, 06/30/2022 - 14:36

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Pioneering recycling turns mixed waste into premium plastics with no climate impact

Scienmag

Only a fraction of the material that could be turned into new plastic is currently recycled. Researchers at Chalmers University of Technology in Sweden have now demonstrated how the carbon atoms in mixed waste can replace all fossil raw materials in the production of new plastic.

New patent expiration for NOVO drug SAXENDA

Drug Patent Watch

Annual Drug Patent Expirations for SAXENDA Saxenda is a drug marketed by Novo and is included in one NDA. It is available from two suppliers. There are twenty-three patents protecting…. The post New patent expiration for NOVO drug SAXENDA appeared first on DrugPatentWatch - Make Better Decisions.