New CRISPR-Based Tool Called PASTE Gene Editing Inserts Large DNA Sequences at Desired Sites
XTalks
DECEMBER 14, 2022
The CRISPR-Cas9 gene editing system uses a programmable single guide RNA sequence (sgRNA) to find and bind to specific regions of DNA and the Cas9 nuclease induces double strand breaks at these target regions of the genome. The researchers reported very few unwanted deletions or insertions at the sites of gene integration.
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