Lilly dives into gene editing

Bio Pharma Dive

Through a deal with Precision Biosciences, the pharma aims to develop therapies for genetic disorders, including Duchenne muscular dystrophy

Gene editing: beyond the hype

Pharma Phorum

Genome editing is an exciting but still nascent field, and companies in the area face as many obstacles as they do opportunities. Zinc fingers are the most common control gene in the body,” Macrae explains. “We Gene therapy can ultimately only take you into the liver,” he explains.

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AbbVie exploring how CRISPR gene editing can improve cell therapies

Bio Pharma Dive

Using technology from Caribou Biosciences, AbbVie hopes to engineer "off-the-shelf" CAR-T cells that can better withstand attacks from the immune system

JPM21: Gene editing for heart disease, a new date to watch in Alzheimer's and Pfizer's deep pockets

Bio Pharma Dive

Verve, a buzzy gene editing startup, unveiled its first drug candidate on Tuesday, while Eli Lilly's and Pfizer's CEO gave updates on Alzheimer's and dealmaking

A CRISPR gene editing treatment continues to show promise for two blood diseases

Bio Pharma Dive

Results from 10 patients with beta thalassemia or sickle cell disease show CRISPR Therapeutics and Vertex's pioneering treatment to be effective, building on earlier study data

Editas, AbbVie rework gene editing deal as pioneering CRISPR trial resumes

Bio Pharma Dive

Development of EDIT-101, the first CRISPR-based therapy to be used in a company-led trial to alter genes within a person's body, will now move forward under Editas' sole ownership

Doudna-founded biotech Caribou raises fresh funds to fuel gene editing pipeline

Bio Pharma Dive

The CRISPR biotech raised $115 million in a Series C financing aimed at advancing its engineered cell therapy research

Beam, Verve stockpile cash as investors bank on gene editing progress

Bio Pharma Dive

Beam expects to receive $260 million through a private stock placement, while Verve raised $94 million to support initial studies of its heart disease treatment

Metagenomi Presents Findings on Three New CRISPR-associated Gene Editing Systems and their Ability to Edit T-Cell and NK-Cell Genomes for Use in Cell Therapy

BioTech 365

Metagenomi Presents Findings on Three New CRISPR-associated Gene Editing Systems and their Ability to Edit T-Cell and NK-Cell Genomes for Use in Cell Therapy Metagenomi Presents Findings on Three New CRISPR-associated Gene Editing Systems and their Ability to Edit T-Cell … Continue reading → Business Wire

Gene-editing produces tenfold increase in superbug slaying antibiotics

Scienmag

Martins Scientists have used gene-editing advances to achieve a tenfold increase in the production of super-bug targeting formicamycin antibiotics. Credit: Dr Dino J.

#news #biotech Researchers invent new gene-editing tool

BioTech 365

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Researchers invent new gene-editing tool.Researchers from the University of Illinois Chicago have discovered a new gene-editing technique that allows for the programming of sequential cuts—or edits—over time.

Japanese consumers more concerned about gene-editing of livestock than of vegetables, survey shows

Scienmag

Credit: Photo by Hisashi Urashima A statistically rigorous survey of Japanese consumers has found that they have more negative opinions about the use of new gene-editing techniques on livestock than they do about use of the same technologies on vegetables.

#news #biotech Researchers analyze consumer preferences for gene edits in the fruit industry

BioTech 365

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Researchers analyze consumer preferences for gene edits in the fruit industry.In states such as California and Florida, the $3 billion orange and citrus industry is big business. … Continue reading → #news

#news #biotech Prime editing enables precise gene editing without collateral damage

BioTech 365

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Prime editing enables precise gene editing without collateral damage.The latest gene editing technology, prime editing, expands the ‘genetic toolbox’ for more precisely creating disease models and correcting … Continue reading → #news

Arbor Biotechnologies and Lonza Enter into Gene Editing Technology Licensing Deal

BioTech 365

Arbor Biotechnologies and Lonza Enter into Gene Editing Technology Licensing Deal Arbor Biotechnologies and Lonza Enter into Gene Editing Technology Licensing Deal The new agreement will provide Lonza with access to Arbor’s gene editing technology Quote from David Cheng, CEO … Continue reading → GlobeNewswire

Verve Therapeutics Announces Data Demonstrating Durable LDL Cholesterol Lowering After a One-Time Gene Editing Treatment in Non-Human Primates

BioTech 365

#news #biotech Precision’s one-time gene editing treatment lowers cholesterol in monkeys for 3 years

BioTech 365

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Precision’s one-time gene editing treatment lowers cholesterol in monkeys for 3 years.Precision’s one-time gene editing treatment lowers cholesterol in monkeys for 3 years arlene.weintraub Fri, 02/19/2021 – … Continue reading → #news

#news #biotech Advancing gene editing with new CRISPR/Cas9 variant

BioTech 365

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Advancing gene editing with new CRISPR/Cas9 variant.Using a new variant to repair DNA will improve both safety and effectiveness of the much-touted CRISPR-Cas9 tool in genetic research, … Continue reading → #news

Researchers recommend more transparency for gene-edited crops

Scienmag

Media contacts: Jennifer Kuzma, jkuzma@ncsu.edu Khara Grieger, kdgriege@ncsu.edu Mick Kulikowski, News Services, 919.218.5937 or mick_kulikowski@ncsu.edu Researchers at North Carolina State University call for a coalition of biotech industry, government and non-government organizations, trade organizations, and academic experts to work together to provide basic information about gene-edited crops to lift the veil on how plants or […].

#news #biotech Genomics, gene-editing and the Blue Revolution

BioTech 365

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Genomics, gene-editing and the Blue Revolution.Aquaculture—the farming of fish and shellfish, is the world’s fastest growing primary industry.

#news #biotech Researchers recommend more transparency for gene-edited crops

BioTech 365

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Researchers recommend more transparency for gene-edited crops.Researchers at North Carolina State University call for a coalition of biotech industry, government and non-government organizations, trade organizations, and academic … Continue reading → #news

A Review of Gene Editing Technology and its Application in Agriculture – ResearchAndMarkets.com

BioTech 365

A Review of Gene Editing Technology and its Application in Agriculture – ResearchAndMarkets.com A Review of Gene Editing Technology and its Application in Agriculture – ResearchAndMarkets.com DUBLIN–(BUSINESS WIRE)–The “Gene Editing Technology and its Application in Agriculture” report has been added … Continue reading → Business Wire

#news #biotech Carnegie Mellon/Yale PNA-based technique an essential part of the gene editing toolkit

BioTech 365

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Carnegie Mellon/Yale PNA-based technique an essential part of the gene editing toolkit.In an article published in the April 8 issue of Nature, the National Institutes of Health’s … Continue reading → #news

#news #biotech Japanese consumers more concerned about gene-editing of livestock than of vegetables, survey shows

BioTech 365

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Japanese consumers more concerned about gene-editing of livestock than of vegetables, survey shows.A statistically rigorous survey of Japanese consumers has found that they have more negative opinions … Continue reading → #news

#news #biotech TALEN gene editing tool more efficient than CRISPR-Cas9 in compact DNA: study

BioTech 365

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: TALEN gene editing tool more efficient than CRISPR-Cas9 in compact DNA: study.TALEN gene editing tool more efficient than CRISPR-Cas9 in compact DNA: study aliu Thu, 01/28/2021 – … Continue reading → #news

Advancing gene editing with new CRISPR/Cas9 variant

Scienmag

Those two key problems – safety and efficacy – are what continue to hold CRISPR-Cas9 gene targeting back from its full clinical potential, explains co-senior author Y. Using a new variant to repair DNA will improve both safety and effectiveness of the much-touted CRISPR-Cas9 tool in genetic research, Michigan Medicine researchers say.

$80 Million-Plus Venture Rounds for Gene Editing, Fusion Protein Companies

BioSpace

Sizable venture rounds from cardiac gene-editing company Verve Therapeutics and the retooled fusion protein maker Vera Therapeutics will push their lead therapies into and through the clinic over the next two years

#news #biotech Research shows potential of gene editing in barley

BioTech 365

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Research shows potential of gene editing in barley.An international team of plant scientists have shown the potential to rapidly improve the quality of barley grain through a … Continue reading → #news

#news #biotech Gene-edited livestock ‘surrogate sires’ successfully made fertile

BioTech 365

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Gene-edited livestock ‘surrogate sires’ successfully made fertile.For the first time, scientists have created pigs, goats and cattle that can serve as viable “surrogate sires,” male animals that … Continue reading → #news

Merit-based NSF grant extension supports expansion of gene-editing technology

Scienmag

Credit: Rasgon Lab, Penn State Researchers who developed an improved method of gene editing for the study of arthropods will expand the technology for use in vertebrate species such as mice, fish and birds after receiving new funding from the National Science Foundation.

EdiGene Announces Approval of its IND Application for its CRISPR/Cas 9 Gene-editing Hematopoietic Stem Cell Therapy ET-01 in ?-thalassemia by China National Medical Products Administration

BioTech 365

EdiGene Announces Approval of its IND Application for its CRISPR/Cas 9 Gene-editing Hematopoietic Stem Cell Therapy ET-01 in ?-thalassemia

#news #biotech Bayer powers gene-editing startup Metagenomi to $65M A round

BioTech 365

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Bayer powers gene-editing startup Metagenomi to $65M A round.Bayer powers gene-editing startup Metagenomi to $65M A round ntaylor Thu, 11/12/2020 – 08:03 from FierceBiotech: Biotech [link].

#news #biotech Gene editing study finds gene for heat tolerance in corals

BioTech 365

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Gene editing study finds gene for heat tolerance in corals.An international research project has used gene-editing technology to examine the heat tolerance of Great Barrier Reef coral … Continue reading → #news

#news #biotech CRISPR, Vertex show CRISPR/Cas9 gene-editing therapy works in more patients

BioTech 365

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: CRISPR, Vertex show CRISPR/Cas9 gene-editing therapy works in more patients.CRISPR, Vertex show CRISPR/Cas9 gene-editing therapy works in more patients ntaylor Thu, 11/05/2020 – 08:52 from FierceBiotech: Biotech … Continue reading → #news

#news #biotech Study uses CRISPR/Cas9-mediated gene editing to study function of insect salivary enzyme

BioTech 365

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Study uses CRISPR/Cas9-mediated gene editing to study function of insect salivary enzyme.Like a scene from a horror movie, tomato fruitworm caterpillars silence their food plants’ cries for … Continue reading → #news

Silk moth’s diapause reverts back to ancestors’ through gene editing!?

Scienmag

Credit: Copyright © 2021, Kunihiro Shiomi, Shinshu University Diapause is a phenomenon in which animals and insects foresee changes in the environment and actively reduce metabolism, or halt regular differentiation and development.

#news #biotech Bayer-backed Metagenomi bumps up series A to $75M as it gears up for gene editing push

BioTech 365

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Bayer-backed Metagenomi bumps up series A to $75M as it gears up for gene editing push.Bayer-backed Metagenomi bumps up series A to $75M as it gears up … Continue reading → #news

Paper: Congress must clarify limits of gene-editing technologies

Scienmag

–Genome editing of human embryos represents one of the most contentious potential scientific applications today. But what if geneticists could sidestep the controversy by editing sperm and eggs instead? Credit: Photo by L. Brian Stauffer CHAMPAIGN, Ill.

Editas names new CEO in latest executive shakeup

Bio Pharma Dive

James Mullen, chair of Editas' board and a former Biogen CEO, will replace Cynthia Collins in a critical year for the gene editing biotech

Gene-edited babies: Current techniques not safe, say experts

The Pharma Data

Current scientific techniques are not yet safe or effective enough to be used to create gene-edited babies, an international committee says. The world’s first gene-edited babies were born in China in November 2018. Why is gene-editing babies controversial?

Beam, capitalizing on stock surge, buys gene therapy tools developer for $120M

Bio Pharma Dive

Guide Therapeutics, the company Beam acquired, is working on ways to more efficiently deliver gene editing therapies into the body

4 storylines at the year's biggest meeting on blood diseases

Bio Pharma Dive

A closely watched gene editing therapy, a slate of new multiple myeloma drugs and much more are set to highlight the American Society of Hematology conference this weekend

Applied StemCell Awarded ~USD 2 mil NIH grant for Advancing its TARGATT Technology for Therapeutic Gene Editing

BioTech 365

ASC), a leading gene editing company focused on the development of enabling tools for cell and gene therapy has been awarded close to $2.0 MILPITAS, Calif.–(BUSINESS –(BUSINESS WIRE)–#AntibodyDiscovery–Applied StemCell, Inc.