Pharmaceutical Technology

JUNE 29, 2023

Experts warn caution around CRISPR gene editing technology on human embryos as it may have dangerous consequences.

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Gene Editing Gene 246

Bio Pharma Dive

JULY 20, 2022

The deal, which is worth $60 million upfront, broadens Vertex’s reach into gene editing and expands Verve’s research beyond heart disease.

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Gene Editing Gene Drugs Development 330

Bio Pharma Dive

FEBRUARY 1, 2022

The collaboration with GenEdit, a South San Francisco startup developing new ways of delivering gene editing tools into the body, dates back to December 2020, but has recently begun to advance.

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Gene Editing Gene Development 330

BioSpace

NOVEMBER 16, 2023

s conditional marketing authorization for Vertex Pharmaceuticals and CRISPR Therapeutics’ gene-edited therapy exa-cel raises some potential safety concerns with the risk of off-target effects.

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Gene Editing Gene Marketing 118

Bio Pharma Dive

JUNE 26, 2021

Results published in The New England Journal of Medicine offer the first clinical evidence that CRISPR gene editing inside the body can be safe and effective, a culmination of years of scientific research.

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Gene Editing Gene Medicine Research 363

Bio Pharma Dive

NOVEMBER 2, 2021

The biotech has identified gene editing as a natural fit for the technology it uses to deliver its vaccines and drugs. A deal with Metagenomi, a startup backed by Bayer, will further those ambitions.

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Gene Editing Gene Vaccination Vaccine 310

Bio Pharma Dive

JULY 23, 2021

The IPO is several times larger than what CRISPR Therapeutics, Intellia and Editas raised several years ago, and ranks well ahead of a more recent offering from gene editing startup Beam.

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Gene Editing Gene 338

Bio Pharma Dive

FEBRUARY 3, 2022

Founded by University of California, Berkeley scientists, Rewrite is studying ways to expand the reach of gene editing beyond limitations of current technologies, including Intellia's.

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Gene Editing Gene Scientist 267

Bio Pharma Dive

JUNE 30, 2021

The companies aim to develop therapies for complement-driven diseases, a specialty of Apellis and relatively new research ground for gene editing.

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Gene Editing Gene Research Development 310

Bio Pharma Dive

JUNE 17, 2021

Capitalizing on investor interest in gene editing, the high-profile startup has secured one of the richest biotech initial public offerings priced this year.

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Gene Editing Gene 297

Pharmaceutical Technology

JANUARY 10, 2023

Asklepios BioPharmaceutical has entered a research partnership and option agreement with ReCode Therapeutics for exploring its single-vector gene-editing platform. The new solution will enable complete gene insertion by delivering the gene-editing tool and DNA as mixed cargo to desired targets in one LNP.

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Gene Editing Gene Gene Therapy Genetics 130

Pharmaceutical Technology

FEBRUARY 23, 2023

Moderna has entered a strategic research and development partnership with ElevateBio’s Life Edit Therapeutics to discover and develop new in-vivo mRNA gene editing therapies. The post Moderna partners with Life Edit for mRNA gene editing therapies appeared first on Pharmaceutical Technology.

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Gene Editing Gene Gene Therapy In-Vivo 147

Bio Pharma Dive

NOVEMBER 15, 2023

Since halting work on a sickle cell treatment early this year, Graphite Bio has laid off staff, shed assets and, now, agreed to be subsumed via a merger with Lenz Therapeutics.

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Gene Editing Gene 271

pharmaphorum

NOVEMBER 1, 2023

Cellectis rockets on gene-editing alliance with AstraZeneca Phil.Taylor Wed, 01/11/2023 - 12:05 Bookmark this

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Gene Editing Gene 101

Bio Pharma Dive

MARCH 2, 2022

A federal patent board ruled Broad Institute scientists were first to a key gene editing advance, weakening the patent position of Intellia and CRISPR Therapeutics, which hold licenses through the University of California.

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Gene Editing Gene Scientist Licensing 202

Drug Discovery World

NOVEMBER 30, 2023

Scientists have used CRISPR gene editing to target and rapidly destroy glioblastoma cells in an approach that could apply to other highly mutated cancers. The post CRISPR gene editing ‘cancer shredding’ technique destroys brain tumours appeared first on Drug Discovery World (DDW).

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Gene Editing Gene Genetics DNA 52

Pharmaceutical Technology

JUNE 15, 2023

Verve Therapeutics and Eli Lilly and Company have entered an exclusive research partnership to advance the former’s preclinical stage in vivo gene editing programme targeting lipoprotein(a) (Lp(a)) to treat atherosclerotic cardiovascular disease (ASCVD).

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Gene Editing Gene Gene Therapy In-Vivo 130

Fierce Pharma

NOVEMBER 16, 2023

But will cost watchdogs embrace the gene-editing therapy? Vertex, CRISPR gain 'historic' nod in UK for exa-cel. kdunleavy Thu, 11/16/2023 - 11:00

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Gene Editing Gene 124

NPR Health - Shots

MARCH 6, 2023

The last time this summit convened in 2018, the world was shocked to hear a scientist had created the first gene-edited babies. He was condemned, but gene-editing has continued, with some success. Image credit: Anthony Wallace/AFP via Getty Images)

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Gene Editing Gene Scientist 133

NPR Health - Shots

MARCH 16, 2023

A Mississippi woman's life has been transformed by a treatment for sickle cell disease with the gene-editing technique CRISPR. All her symptoms from a disease once thought incurable have disappeared. Image credit: Orlando Gili for NPR)

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Gene Editing Gene 145

pharmaphorum

JANUARY 29, 2021

Cutting edge’ is, for once, a truly apt description when it comes to gene editing – both because the field is pushing medicine into areas we might never have dreamed possible, and because these technologies involve literally cutting DNA at a specific point in the genome. Zinc fingers. That would just slow the whole field down.

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Gene Editing Gene Gene Therapy In-Vivo 145

Medical Xpress

MAY 1, 2023

Gene-editing therapy aimed at two targets—HIV-1, the virus that causes AIDS, and CCR5, the co-receptor that helps the virus get into cells—can effectively eliminate HIV infection, new research from the Lewis Katz School of Medicine at Temple University and the University of Nebraska Medical Center (UNMC) shows.

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Gene Editing Gene Medicine Drugs 124

Bio Pharma Dive

OCTOBER 3, 2022

Shares in LogicBio had lost nearly all their value since a 2018 IPO, bringing the company to the brink of Nasdaq delisting. The buyout deal represents a premium of over 600%.

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Gene Editing Gene 356

Bio Pharma Dive

FEBRUARY 22, 2023

The messenger RNA specialist said Wednesday it is teaming up with Life Edit Therapeutics to develop therapies that can modify genes “in vivo.”

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Gene Editing Gene In-Vivo RNA 259

Bio Pharma Dive

OCTOBER 3, 2023

The longtime partners believe that, by combining their technologies, they can create “in vivo” genetic medicines for nervous system and muscular disorders.

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Gene Editing In-Vivo Gene Genetics 260

BioSpace

JUNE 14, 2023

Eli Lilly has secured the rights to Verve Therapeutics’ gene editing approach, a “one-and-done” method that the companies hope will lower the cardiovascular risk factor lipoprotein(a).

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Gene Editing Gene 98

Drug Discovery World

JANUARY 12, 2023

Scientists use complex gene editing and disease modeling systems to gain insights on the potential of CRISPR. . Most gene editing studies are performed in traditional 2D culture systems that model a simplified version of the tissue and biology in question. Limitations of organoids.

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Gene Editing Gene Drugs In-Vivo 98

STAT News

FEBRUARY 22, 2023

Moderna is aiming to build a gene editing franchise powered by some of the same technologies used in its COVID-19 vaccines. The Cambridge biotech company announced Wednesday that it will partner with Life Edit Therapeutics to develop potentially permanent treatments for rare genetic diseases and other conditions.

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Gene Editing Gene Gene Therapy Genetic Disease 126

Bio Pharma Dive

JUNE 9, 2023

The regulator will issue separate verdicts on the pioneering treatment’s use in sickle cell disease and beta thalassemia, with the first expected late this year.

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Gene Editing Gene Drugs Regulation 324

Bio Pharma Dive

NOVEMBER 8, 2023

A gene editing therapy developed by Vertex Pharmaceuticals and CRISPR Therapeutics can mute sickle cell disease’s most damaging symptoms. Yet treatment may not be as simple as its dramatic benefit makes it seem.

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Gene Editing Gene Development 326

NPR Health - Shots

MARCH 8, 2023

The Third International Summit on Genome Editing concluded Monday with ethicists warning scientists to slow down efforts to use gene-editing to enhance the health of embryos. Image credit: Mark Schiefelbein/AP)

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Gene Editing Gene Genome Genomics 98

Bio Pharma Dive

OCTOBER 31, 2023

Expert advisers are reviewing the companies’ case for approval of what could be the first medicine based on the gene editing technology. Follow their discussion here.

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Gene Editing Gene Medicine 330

Bio Pharma Dive

OCTOBER 31, 2023

The high-profile meeting focused on the theoretical risks of CRISPR gene editing, as both the FDA and its advisory committee appeared convinced by the efficacy of the companies’ exa-cel treatment.

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Gene Editing Gene 336

BioSpace

MAY 17, 2023

AstraZeneca Deepens Gene Editing Capabilities with Revvity Partnership 5/18/2023

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Gene Editing Gene 100

Bio Pharma Dive

OCTOBER 11, 2023

Once the specialty of a few select drugmakers, CRISPR gene editing is now an essential technology for a growing group of biotechs, many led by former students of the field's pioneering scientists.

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Gene Editing Gene Scientist 355

XTalks

DECEMBER 14, 2022

Expanding upon the CRISPR-Cas9 gene editing system, researchers at MIT have designed a new technique called PASTE gene editing that can cut out defective genes and replace them with new genes in a safer and more efficient way. The PASTE gene editing technique was recently published in Nature Biotechnology.

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Gene Editing Gene DNA Gene Sequencing 98

Bio Pharma Dive

JANUARY 12, 2021

Verve, a buzzy gene editing startup, unveiled its first drug candidate on Tuesday, while Eli Lilly's and Pfizer's CEO gave updates on Alzheimer's and dealmaking.

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Gene Editing Gene Drugs 189