BioTech 365

MAY 5, 2021

First of its kind SARS-CoV-2 detection by partial N gene sequencing now publicly available at CLIA Certified Milford Connecticut laboratory First of its kind SARS-CoV-2 detection by partial N gene sequencing now publicly available at CLIA Certified Milford Connecticut laboratory … Continue reading →

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Gene Sequencing Gene 52

Medical Xpress

FEBRUARY 1, 2023

Next-generation cancer strategies rely on next-generation gene sequencing (NGS), which paves the way for new techniques and tools to detect mutations and determine patient therapy.

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Gene Sequencing Gene Research Genetics 75

BioSpace

AUGUST 24, 2021

The development of COVID-19 vaccines, which took only months from the initial gene sequencing to the time shots were in arms, was the biggest story of 2020 alongside the pandemic itself.

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Gene Sequencing Gene Vaccination Vaccine 98

pharmaphorum

JUNE 23, 2022

Systemic administration of gene-editing drugs would avoid that process with an “off-the-shelf” option for a one-shot, potentially curative treatment for diseases associated with genetic mutations.

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Gene Editing In-Vivo Gene Sequencing Gene 97

Scienmag

JULY 6, 2021

New method yields 10 times more data, reduces gene sequencing costs by one third Researchers have devised a way to multiply by more than ten-fold the accessible details of gene activity in individual cells.

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Gene Sequencing Gene Research Development 75

Scienmag

JUNE 1, 2022

New research led by scientists at the Milner Centre for Evolution at the University of Bath suggests that determining evolutionary trees of organisms by comparing anatomy rather than gene sequences is misleading.

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Gene Sequencing Gene Scientist Research 54

XTalks

DECEMBER 14, 2022

The objective of Abudayyeh and Gootenberg’s research was to develop a gene editing tool that can facilitate the splicing and replacement of a defective gene sequence without double-stranded breaks in DNA. The researchers reported very few unwanted deletions or insertions at the sites of gene integration.

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Gene Editing Gene DNA Gene Sequencing 98

Scienmag

MAY 4, 2021

Credit: Elizabeth Cooke Next-generation gene sequencing (NGS) technologies –in which millions of DNA molecules are simultaneously but individually analyzed– theoretically provides researchers and clinicians the ability to noninvasively identify mutations in the blood stream.

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Gene Gene Sequencing Research DNA 64

pharmaphorum

JANUARY 5, 2023

The data was from their phase 2b trial of a personalised vaccine consisting of 34 mRNAs, each targeting mutations – identified by gene sequencing – thought to be driving a patient’s cancer. The post Boost for mRNA as Moderna to acquire OriCiro for $85 million appeared first on.

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Gene Sequencing Vaccination Vaccine DNA 97

BioTech 365

DECEMBER 3, 2020

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Research team develops software that cuts time, cost from gene sequencing.A team of Johns Hopkins University researchers has developed a new software that could revolutionize how DNA … Continue reading →

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Gene Sequencing Gene Research DNA 40

pharmaphorum

DECEMBER 14, 2022

The two partners have revealed the first clinical data from a phase 2b trial of a personalised vaccine consisting of 34 mRNAs, each targeting mutations – identified by gene sequencing – that are thought to be driving a patient’s cancer.

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Vaccination Vaccine Trials Gene Sequencing 98

pharmaphorum

FEBRUARY 23, 2022

Interest in non-viral methods of delivering gene therapies has been growing in the face of current scrutiny of the safety of viral vectors like adeno-associated viruses (AAV), with a number of clinical programmes based on AAV under clinical holds imposed by the FDA.

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Gene Therapy Gene Gene Sequencing Immune Response 105

pharmaphorum

OCTOBER 12, 2022

The neoantigens are selected based on gene sequencing of either a tumour biopsy or a blood sample, with an individual vaccine tailored to the patient manufactured and administered in a matter of weeks.

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Vaccination Vaccine Gene Sequencing RNA 105

pharmaphorum

MARCH 10, 2022

Scenic’s platform technology Cell-Seq is used to seek out genetic modifiers, defined as gene sequences that counteract the effect of another disease-associated gene.

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Genetics Gene Sequencing Gene Clinical Trials 98

BioTech 365

APRIL 20, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Algorithm maps gene expression in space.As we accumulate more and more gene-sequencing information, cell-type databases are growing in both size and complexity.

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Gene Expression Gene Gene Sequencing Research 40

pharmaphorum

AUGUST 10, 2021

The three-year project – led by respiratory medicine expert Dr Timothy Hinks from the Oxford University Respiratory Medicine Unit – will use whole-genome sequencing of around 500 patients with severe asthma, comparing their gene sequences with control subjects who don’t have asthma.

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Gene Sequencing Gene Bioinformatics Genome 116

BioTech 365

FEBRUARY 4, 2021

GenapSys), the company behind the world’s first highly accurate, affordable, and accessible gene sequencer, today announced it has named Jason Myers as its Chief Executive … Continue reading → GenapSys Names Jason Myers CEO GenapSys Names Jason Myers CEO REDWOOD CITY, Calif.–(BUSINESS

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Gene Sequencing Gene 40

Drug Discovery World

MARCH 20, 2023

The investigators found the two risk genes, SRRM2 and AKAP11, by comparing the gene sequences of people with schizophrenia to those of healthy controls. Next, the researchers plan to assess whether and how these genes may have a clinical role and to identify drugs that might target the genes in the study.

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Gene Research Gene Sequencing Genetics 52

Roots Analysis

FEBRUARY 21, 2022

Since the introduction of a gene sequencing method by Frederick Sanger in 1977, the field of genomic data collection and analysis has evolved significantly. Advancement in DNA sequencing technologies have resulted in noteworthy developments in various healthcare-related research fields, such as diagnostics and personalized medicine.

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Gene Sequencing Reagent RNA Genome 52

Drug Discovery World

JULY 24, 2023

Ginkgo will leverage innovative technologies enabled by its high-throughput, automated Foundry and its proprietary genetic data Codebase, a portfolio of reusable biological assets which includes more than one billion proprietary gene sequences.

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Protein Gene Sequencing Antibody Radiology 52

Drug Discovery World

APRIL 17, 2023

Genetic sequencing To assess these alterations in groups of different ancestries, Walch and colleagues analysed targeted DNA sequencing data from 4,441 patients treated for colorectal cancer at MSK between 2014 and 2022. Tumours were sequenced using MSK-IMPACT, a gene sequencing panel that looks for mutations in up to 505 genes.

Genome 52

Genome Genomics Gene Sequencing Genetics 52

pharmaphorum

AUGUST 10, 2021

The decision was taken by the UUS regulator after a case of a rare blood cancer (myelodysplastic syndrome) was seen in a patient treated with Skysona that probably arose as a result of the lentiviral vector used to deliver the gene therapy.

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Gene Therapy Gene Genetic Disease Marketing 135

pharmaphorum

SEPTEMBER 14, 2022

Meanwhile, a third gene therapy candidate – SPVN30, which combines the gene sequences in SPVN06 and SPVN20 – is in early development for RP. The post SparingVision raises €75m for eye disease gene therapies appeared first on.

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Gene Therapy Gene Gene Sequencing Gene Editing 52

pharmaphorum

MARCH 15, 2022

Gene sequencing specialist Illumina has started rolling out a new test that looks for a battery of tumour-associated genes from a single tissue sample, and could be used to help guide treatment for a broad range of cancers.

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Gene Gene Sequencing Clinical Trials Clinical Trials 52

Pharmaceutical Technology

MAY 26, 2023

As per the company, dbDNA is suitable for rapid, scalable manufacture of GMP DNA and can incorporate gene sequences of sizes ranging from 500bp to 20kb, which are typically unstable as pDNA.

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DNA Manufacturing Gene Therapy Gene 130

pharmaphorum

MAY 18, 2021

The advantage of plant-based production is that it is quick – Medicago says it produced the main ingredient for its vaccine just 20 days after the gene sequence of SARS-CoV-2 was published – and is easily scalable simply by cultivating additional plants.

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Vaccination Vaccine Gene Sequencing Immune Response 64

pharmaphorum

AUGUST 21, 2020

Cambridge, UK-based Biofidelity has raised $12 million in first-round funding for its cancer diagnosis platform, which can detect mutations quicker than current approaches like gene sequencing.

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Gene Sequencing DNA FDA Approval Genetics 59

pharmaphorum

APRIL 23, 2021

The alliance is based on Obsidian’s cytoDRIVE platform, which uses already approved small-molecule drugs alongside gene-editing medicines to control the expression of protein from a gene sequence. For example, adding a small-molecule might stabilise the medicine, allowing levels of the target protein to increase.

Genetics 52

Genetics Gene Editing Drugs Gene 52

Drug Discovery World

AUGUST 5, 2022

Evonetix believes this will break dependence on the service provider approach giving users the power to prepare gene sequences rapidly in their own laboratories. The result is a platform that has been designed from the ground up to be a benchtop DNA synthesis system. Why enzymatic synthesis?

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DNA Gene Sequencing Gene Gene Therapy 52

pharmaphorum

FEBRUARY 22, 2021

That therapy uses an adeno-associated virus (AAV) as a vector rather than a lentivirus, a vector type that features in approved gene therapies such as Roche’s Luxturna and Novartis’ Zolgensma. million in Europe.

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Gene Therapy Gene Gene Sequencing Gene Expression 52

Roots Analysis

OCTOBER 16, 2023

DNA and Gene Cloning involves the isolation of a DNA sequence of any species ( often a gene ) and its insertion into a vector to enable growth without any alteration in the original DNA sequence. These clones can be manipulated and mutated in vitro to alter the expression and function of a protein.

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DNA Gene Protein In-Vitro 40

pharmaphorum

FEBRUARY 19, 2021

“Since 2020 there has been a 50% increase in sequences produced in African countries. This is a priority area for us to ensure that all African countries are equipped to carry out gene sequencing locally or can send samples to reference laboratories.”. Novavax has also signed a deal to provide 1.1

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Vaccination Vaccine Gene Sequencing Gene 64

The Pharma Data

DECEMBER 28, 2020

Combining next generation sequencing (“NGS”) with its technology platform, the Company performs full-gene sequencing with deletion/duplication analysis in an array of panels that can be tailored to meet specific customer needs.

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Genetics Gene Sequencing Antibody Gene 52

Drug Discovery World

SEPTEMBER 28, 2023

This is the latest episode of the free DDW narrated podcast, “Overcoming different barriers in drug discovery”, which covers three articles written for Volume 23, Issue 3 – Summer 2022 of DDW.

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Drugs Development Gene Sequencing DNA 52

Drug Discovery World

MARCH 27, 2023

Advances in sequencing are leading to scientific breakthroughs in preventative care, faster diagnoses, and proactive medical interventions. Genomics is driving a revolution in drug development and, in the long run, the state of public healthcare. Jack Dix , Head of Healthcare Strategy and Consulting at Kainos, expands.

Genome 52

Genome Genomics Research Drugs 52

Roots Analysis

FEBRUARY 23, 2022

Over the past few years, several companies have started offering a diverse range of genome sequencing products and services using various second and third generation sequencing technologies.

Genetics 52

Genetics RNA Gene Therapy DNA 52

Drug Discovery World

DECEMBER 13, 2022

PacBio, developer of sequencing solutions, has announced its HiFi sequencing technology will be used in a pilot project for the Children’s Rare Disease Cohorts Initiative (CRDC) at Boston Children’s Hospital. .

Genetics 52

Genetics Research Genome Genomics 52