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13th PM Society Digital Awards – celebrating creative innovation

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Meanwhile, Prescript Communications – which had designed Novartis’ Kesimpta Digital Training Portal, the Bronze winner of the Internal Communications category – said that the company itself had been fortunate to undergo its own creative digitalisation makeover process before being approached for the project, having foreseen developing trends.

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Roche scores phase 3 win for subcutaneous Tecentriq, eyes filings

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The results of the IMscin001 study found that an injection of Tecentriq under the skin taking just a few minutes was non-inferior to a 30 to 60-minute infusion with the IV version in terms of pharmacokinetics – how the active ingredient behaves in the body after administration. Results from a trial in first-line NSCLC are due in early 2023.

Trials 105
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BMS buys into AI-designed immune drug from Exscientia

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The cash injection and BMS alliance have made Exscientia one of the most well-funded biotechs in the AI category and allowed it to bulk up its capabilities with the acquisition of Austrian rival Allcyte for $61 million in June.

Drugs 98
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AI specialist Insilico raises $60m as more projects head to clinic

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Along with bringing forward additional drugs in its pipeline, the cash injection will be used to continue development of its Pharma.AI The first quarter of 2022 is reported to be the slowest in three years for new financings in the biopharma category, coming after record levels in 2020 and 2021.

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Blackstone funds new trials of Sanofi’s Sarclisa in myeloma

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Blackstone will provide €300 million in funding for the project, which will focus on a subcutaneous formulation of Sarclisa (carfilzomib) that is due to start a pivotal study later this year. Sanofi has partnered with drug delivery specialist Enable Injections to develop the subcutaneous formulation.

Trials 97
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Welsh startup Antiverse raises $2m for antibody discovery toolkit

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It’s one of the few AI drug discovery companies operating in the antibody category, as most are focused on small molecules. The Cardiff, Wales startup is combining machine learning and phage display techniques to model antibody-antigen binding and says it can cut the time it takes to develop a drug candidate.

Antibody 101
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GSK preps filing for novel antibiotic for urinary tract infections

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Another study called EAGLE-1 is comparing two oral doses of gepotidacin to a regimen based on an intramuscular injection of ceftriaxone and oral azithromycin in the treatment of urogenital gonorrhoea. There are real concerns that we could be entering a post-antibiotic era, where even minor infections can be enough to kill patients.