Remove tag long-covid
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Grand Rounds April 14, 2023: RECOVER in Action – Status of Clinical Trial Protocols (Kanecia Zimmerman, PhD, MD, MPH)

Rethinking Clinical Trials

RECOVER has used cohort data to identify major symptom clusters and develop 5 platform protocols that will investigator priority symptom clusters and their causes; test known and novel interventions across domains; and evaluate treatments to improve Long COVID symptoms. It’s all over the place.

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Grand Rounds October 27, 2023: Digital, Decentralized and Democratized: Lessons From The Yale PaxLC Trial (Harlan M. Krumholz, MD, SM)

Rethinking Clinical Trials

Tags #pctGR, @Collaboratory1 The post Grand Rounds October 27, 2023: Digital, Decentralized and Democratized: Lessons From The Yale PaxLC Trial (Harlan M. One of the main reasons we turn people away is because they are taking a medication that does not work with Paxlovid. Krumholz, MD, SM) appeared first on Rethinking Clinical Trials.

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Grand Rounds October 28, 2022: The HERO (Healthcare Worker Exposure Response & Outcomes) Program: An Online Community to Support Observational Studies, Randomized Trials, and Long-Term Safety Surveillance (Emily O’Brien, PhD, FAHA; Russell Rothman, MD, MPP)

Rethinking Clinical Trials

HERO Registry; HERO TOGETHER; Hydroxychloroquine; COVID-19; PCORI; PCORnet. On March 21, 2020, in response to the COVID-19 pandemic, PCORI contacted leadership at Duke Clinical Research Institute and PCORnet and a decision was made to focus on the space of healthcare workers. Vanderbilt University Medical Center. Key Points.

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Grand Rounds August 5, 2022: Economic Evaluation of Platform Trial Designs (Jay JH Park, PhD, MSc)

Rethinking Clinical Trials

Participants were asked how long it takes and cost for trail set up, conduct, and analysis for a two-arm multi-trial and in addition for a platform trial how long it takes what it costs to add a new intervention. The response rate was low (10%). Discussion Themes. Calling them out is step one. Read the full study.

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Clover Biopharmaceuticals Announces Publication of Phase 1 Clinical Trial Data for its Adjuvanted COVID-19 Vaccine Candidates in The Lancet

The Pharma Data

Adjuvanted S-Trimer COVID-19 vaccine candidates demonstrated favorable safety and tolerability profiles and strong neutralizing immune responses in a phase 1 trial. The study found that Clover’s adjuvanted S-Trimer COVID-19 vaccine candidates were well tolerated and safe. CHENGDU, China , Feb.

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Will Plant-Based Meat Prices Ever Be Lower Than Real Meat?

XTalks

A growing trend toward plant-based eating and distrust in the safety of meat brought on by the COVID-19 pandemic has transformed plant-based meat into a popular alternative rather than a niche product enjoyed only by vegans and vegetarians. But yet, the price tag is still higher than real meat. How Long Will Price Parity Take?

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Establishing Safer Food Supply Chains with Blockchain and IoT

XTalks

Despite enhanced safety measures brought on by the COVID-19 pandemic, consumers are still skeptical about the safety, source and quality of the foods they buy, according to a new survey. Food fraud is a $40 billion a year problem and ends up costing companies much more to repair the damage done to their reputations in the long run.