Remove tag mabs
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Grand Rounds January 12, 2024: Design and Implementation of a Weighted Lottery to Equitably Allocate Scarce Covid-19 Resources (Erin K. McCreary, PharmD, BCIDP)

Rethinking Clinical Trials

The first monoclonal antibody (mABs) treatment for treatment of COVID-19 was approved in November 2020. Clinicians wrote a consult for mABs and the pharmacy delivered whichever mAB that was available. When Evusheld was approved in December 2021 a similar weighted lottery process was put into place.

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This week in drug discovery (24-28 October)

Drug Discovery World

Click’ chemistry used to tag proteins made by cancer cells . A panel of investigational monoclonal antibodies (mAbs) targeting different sites of the Epstein-Barr virus (EBV) have been shown to block infection when tested in human cells in a laboratory setting. . . Millions invited to join UK’s largest health research programme .

Drugs 52
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What to expect from PEGS Europe 2023: Day 3

Drug Discovery World

Laura Mele, PhD, Investigator, GlaxoSmithKline, on: ‘Discovery and characterisation of highly potent Fc-enhanced anti-GPCR mAbs’. Fabian Mohr, PhD, Vice President Research & Development, IBA Lifesciences, on: ‘Developing a robust affinity tag platform using engineered streptavidin’.

Protein 59
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Merck KGaA raises full-year forecast; Perlmutter’s new gig tackles ‘undruggable targets’

The Pharma Data

New variant-hardy AbCellera-Lilly mAb shows utility of viral genomics surveillance ( BioCentury ). AbbVie’s Humira regains top pharma TV spender spot, while sibling brands Rinvoq and Skyrizi tag along ( Fierce ). The weird science of the placebo effect keeps getting more interesting ( Vox ).