Delveinsight

AUGUST 6, 2020

Taysha raises USD 95 Million to take 4 CNS gene therapies into the clinic. Taysha Gene Therapies has raised USD 95 million to take four gene therapies into humans. FDA turns back peanut allergy patch of DBV Technologies. Combating COVID-19 by luring the virus away from human cells with a decoy target.

Allergies 53

Allergies Vaccination Vaccine Gene Therapy 53

pharmaphorum

NOVEMBER 16, 2022

There’s plenty in the pipeline to entice a potential buyer, however, including several mid-stage clinical candidates, such as EPO inhibitor LKA651 for diabetic retinopathy, Factor B inhibitor iptacopan for AMD, and gene therapy PPY988 for geographic atrophy.

Sales 124

Sales Gene Therapy Allergies Medicine 124

XTalks

NOVEMBER 30, 2023

More Investigational Therapies for HIV Are on the Way American Gene Technologies, a pioneering biotech company headquartered in Rockville, Maryland, has released promising results from its Phase I trial of AGT103-T, a gene therapy designed for individuals with chronic HIV disease.

FDA Approval 111

FDA Approval Gene Therapy Clinical Trials Clinical Trials 111

XTalks

NOVEMBER 6, 2020

The Burnaby, BC-based company developed the oral DNA-based vaccine using its proprietary bacTRL Gene Therapy Platform, which uses genetically modified bifidobacteria as carriers of genetic vaccine elements on a DNA plasmid. Related: Red Meat Allergy Test Gets FDA Clearance. “We BacTRL Gene Therapy Platform.

Clinical Trials 75

Clinical Trials Clinical Trials Vaccination Vaccine 75

Drug Discovery World

JANUARY 31, 2024

Recent technological success includes last year’s landmark approval by the MHRA of the first gene therapy for sickle-cell disease and transfusion-dependent β-thalassemia, a treatment from Vertex and CRISPR Therapeutics.

Gene Therapy 52

Gene Therapy Allergies Scientist Gene 52

pharmaphorum

SEPTEMBER 17, 2021

Havas Life Medicom, ARK and Pharmadoctor top the agency charts AstraZeneca, klarify and Novartis Gene Therapies top the pharma leader board. Among pharma companies and healthcare organisations, the top three companies, taking two Golds each, were AstraZeneca, klarify and Novartis Gene Therapies. Market Access. ARK for AZ.

Gene Therapy 52

Gene Therapy Allergies Gene Life Science 52

pharmaphorum

NOVEMBER 30, 2022

Working in the allergy and autoimmune space, COUR looks at nanoparticles and allergens – such as peanut and coeliac (which he had experience with whilst at Takeda) – and infuses these into patients as a treatment so that the body accepts it because of the precise combination technology, patients forming a tolerance to the antigen.

Life Science 97

Life Science Pharma Companies Sales Marketing 97

The Pharma Data

AUGUST 7, 2020

As the pharma industry stands firm in its commitment to advance the sector to fight Covid-19, news has emerged from the European Commission who intend to streamline the development of therapies using genetically modified organisms to treat Covid-19. Regenerative medicine and advanced therapies thriving despite Covid-19 disruption.

Clinical Trials 52

Clinical Trials Clinical Trials Gene Trials 52

The Pharma Data

AUGUST 5, 2021

Bayer recently formed its own cell and gene therapy platform as part of its transformation strategy for Pharmaceuticals. The platform already has potentially ground-breaking medical innovations in clinical development, such as a therapy for the treatment of Parkinson’s. in sales in the Allergy & Cold category.

Sales 52

Sales Production Gene Therapy Allergies 52

XTalks

DECEMBER 20, 2023

Bayer’s Astepro (azelastine), an over-the-counter medication for cold, flu and allergies, led the pack in the first half of 2023 with 7.4 This included the approval of several cell and gene therapies and significant technological advancements such as the incorporation of AI and machine learning in drug development and medical imaging.

Life Science 59

Life Science Clinical Trials Clinical Trials FDA Approval 59

Pharmaceutical Technology

JULY 18, 2022

The KidCOVE trial is being carried out in partnership with the National Institutes of Health (NIH) unit National Institute of Allergy and Infectious Diseases (NIAID). Cell & Gene Therapy coverage on Pharmaceutical Technology is supported by Cytiva. Topic sponsors are not involved in the creation of editorial content.

Vaccination 246

Vaccination Vaccine Gene Therapy Antibody 246

Scienmag

OCTOBER 26, 2020

Researchers at Yale University and the Broad Institute of MIT and Harvard screened hundreds of millions of cells exposed to the COVID-19 and MERS viruses and identified dozens of genes that both enable the viruses to replicate in cells and also those that seem to slam the door on the virus. The pro-viral and anti-viral […].

Gene 74

Gene Research Gene Therapy Allergies 74

Scienmag

FEBRUARY 11, 2021

MUSC Hollings Cancer Center researcher finds loss of STING in recipient dendritic cells increases GVHD severity Credit: MUSC Hollings Cancer Center MUSC Hollings Cancer Center researcher Yongxia Wu, Ph.D., identified a new target molecule in the fight against graft-versus-host disease (GVHD).

Research 53

Research Gene Therapy Allergies Gene 53

Roots Analysis

MARCH 16, 2023

The following points illustrate the key applications of mRNA therapeutics and vaccines: Allergy Tolerization Therapies: Plasmid DNA and mRNA vaccines that encode for allergens have been demonstrated to be capable of inducing T helper 1 cells and T regulatory responses, which, in turn, can modulate allergic reactions caused due to T helper 2 cells.

Vaccination 52

Vaccination Vaccine DNA Protein 52

Scienmag

DECEMBER 3, 2020

A new study has found that a novel T cell genetically engineered by University of Arizona Health Sciences researchers is able to target and attack pathogenic T cells that cause Type 1 diabetes, which could lead to new immunotherapy treatments.

Genetic Engineering 40

Genetic Engineering Engineer Genetics Bacteria 40

Eye on FDA

AUGUST 27, 2023

The committee that had the sole negative recommendation was from the Gastrointestinal Drugs Advisory Committee which did not recommend approval for an NDA involving a treatment for pre-cirrhotic liver fibrosis due to NASH.

Drugs 78

Drugs Gene Therapy Allergies Medicine 78

Drug Discovery World

NOVEMBER 9, 2023

Advances in discovery and engineering of antibodies for non-cancer targets This session will feature a range of presentations which include: Joshua Tan, PhD, Chief, Antibody Biology Unit, National Institute of Allergy and Infectious Diseases, National Institutes of Health, on: ‘Discovery of broadley-neutralising antibodies against Coronaviruses’.

Engineer 52

Engineer Antibody Protein In-Vivo 52

pharmaphorum

JULY 26, 2022

The hope of being able to provide a functional or complete cure for AIDS is being raised by the prospect of utilising recent developments in the industry, including gene therapy and mRNA vaccines. Gene therapies are another approach that has been validated with approvals in recent years.

Gene Therapy 140

Gene Therapy Protein Vaccination Vaccine 140

The Pharma Data

APRIL 27, 2021

to €283 million, reflecting growth of Digestive and Mental Wellness categories as well as Allergy partially offset by the decline of the Pain category. Development for Dupixent ® for grass allergy has been discontinued. At CER, BOI increased 48.6%. The ratio of BOI to net sales was 40.5% (and 27.5% Consumer Healthcare. Change at CER.

Sales 52

Sales Vaccination Vaccine Medicine 52

Pfizer

SEPTEMBER 28, 2022

Pfizer and Sangamo Therapeutics Announce Phase 3 Trial of Investigational Gene Therapy for Hemophilia A Has Re-Opened Recruitment. Pfizer-BioNTech COVID-19 Vaccine, Bivalent (Original and Omicron BA.4/BA.5), 5), COMIRNATY® (COVID-19 Vaccine, mRNA) and Pfizer-BioNTech COVID-19 Vaccine. 5) could cause a severe allergic reaction.

Vaccination 101

Vaccination Vaccine Medicine Clinical Trials 101

Pfizer

OCTOBER 19, 2022

Tell your vaccination provider about all of your medical conditions, including if you: have any allergies. Pfizer and Sangamo Therapeutics Announce Phase 3 Trial of Investigational Gene Therapy for Hemophilia A Has Re-Opened Recruitment. Pfizer-BioNTech COVID-19 Vaccine, Bivalent (Original and Omicron BA.4/BA.5), have a fever.

Vaccination 40

Vaccination Vaccine Clinical Trials Clinical Trials 40

XTalks

AUGUST 2, 2023

Meanwhile, BioMarin’s gene therapy Roctavian is approved by the FDA for the treatment of hemophilia A. Onureg (azacitidine), a leukemia therapy, also saw large growth of 70 percent to $124 million in 2022, and the multiple sclerosis drug Zeposia (ozanimod) generated $250 million in 2022, an 87 percent increase.

Sales 98

Sales Manufacturing FDA Approval Life Science 98

XTalks

DECEMBER 24, 2020

From rare disease drug approvals to treatments involving immunotherapies and gene therapies and awarding of a Nobel Prize to the inventors of the gene-editing tool CRISPR, 2020 was a year of great activity and productivity despite the backdrop of the pandemic. Vaccine Considerations. CRISPR Therapeutics.

Life Science 111

Life Science Vaccination Vaccine Gene 111

pharmaphorum

FEBRUARY 16, 2022

Novartis’ gene therapy Zolgensma (onasemnogene abeparvovec-xioi) for SMA. More deals have followed including for non-small cell lung cancer treatment Tecentriq (atezolizumab) and for the most expensive treatment in the world, gene therapy Libmeldy (atidarsagene autotemcel), to treat metachromatic leukodystrophy (MLD).

Marketing 52

Marketing Life Science Medicine Gene Therapy 52

Eye on FDA

JANUARY 11, 2021

There were 104 releases involving approvals (compared to 92 the previous year) – 58 of which were about the approval of drugs; 42 of which involved the approval of devices; 1 gene therapy; 1 involving an animal product and 2 of which were vaccines.

Gene Therapy 66

Gene Therapy Vaccination Vaccine Allergies 66