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LabCorp’s Innovative High-Speed COVID-19 Test Gets Emergency Use Authorization from the FDA

XTalks

While the new test is based on RT-PCR molecular detection, it utilizes a high-throughput technique involving a new heat-based extraction method and enhanced technology to extract RNA from samples for COVID-19 testing. The novel method significantly increases testing efficiency while decreasing the need for testing reagents and supplies.

Reagent 98
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Transforming Biomanufacturing: Potential of Cell Free Systems

Roots Analysis

Biomanufacturing utilizing cell free systems is an emerging area of research that enables the synthesis of different biomolecules, such as cytotoxic proteins, fusion proteins, post translationally modified proteins, antibodies, enzymes, vaccines and other complex proteins, without the use of living cells.

Protein 52
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Receptor Occupancy Assays by Flow Cytometry: Benefits for Clinical Trials

XTalks

Generally, antibody-based therapeutics are one of the main types of drugs that are assessed using receptor occupancy assays as they bind to specific cell surface receptors through which they impact downstream intracellular signalling pathways. The antibodies are conjugated to fluorochromes for them to be detected.

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Reflecting on PEGS Europe 2023 

Drug Discovery World

The company’s goal is to accelerate functional characterisation and shortenoptimisation time in antibody discovery and t-cell workflows. coli expression systems and is using high-throughput expression pipelines to screen constructs for optimal expression to generate protein and cellular reagents.

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CRISPR breakthroughs: New solutions for common diseases

Drug Discovery World

Nucleic acid-based diagnostics, which typically require PCR reagents and laboratory equipment, are crucial for identifying, treating, and preventing common infectious diseases. CRISPR diagnostics have successfully detected various pathogens, including RNA viruses (eg. Herpesviridae, Polyomaviridae, and Papillomaviridae), bacteria (e.g.,

DNA 98
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Reflections from AACR 2023

Drug Discovery World

Jordan also commented on a resurgence in antibody drug conjugates (ADCs), noting the higher drug loading, better payload stability, better tissue penetrance, and thinks that will continue. From that, we’ll understand better how to use targeted therapies.” It’s a 1.5 It’s really all driven by the Archer technology.

Protein 52
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Flow cytometry technologies and cancer associated fibroblasts

Drug Discovery World

used conventional flow cytometry analysis and FACS (fluorescence-activated cell sorting) to validate a pan-CAF marker along with CAF subpopulation-specific markers identified using single-cell RNA sequencing 3. For imaging mass cytometry, heavy metal-conjugated antibodies are added simultaneously to a tissue section adhered to a slide.