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Swiss scientists identify a virus that kills dormant bacteria

Drug Discovery World

Researchers have found a virus that kills dormant bacteria, a discovery that could help to combat infections that can’t be treated with antibiotics. For the first time, ETH Zurich researchers in Switzerland have isolated a bacteriophage from rotting plant material that can attack and kill bacteria in a dormant state.

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A gene in tuberculosis bacteria is found essential for siderophore secretion and virulence

Scienmag

of the University of Alabama at Birmingham have made what they call “a major step” in understanding how Mycobacterium tuberculosis acquires iron from its human host — a process essential for the pathogenesis of this bacterium. . – Lei Zhang, Ph.D., and Michael Niederweis, Ph.D.,

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Scientists discover small RNA that regulates bacterial infection

The Pharma Data

Pseudomonas aeruginosa, a common environmental bacterium, can colonize different body parts, such as the lungs, leading to persistent, chronic infections that can last a lifetime – a common occurrence in people with cystic fibrosis. “Our study took a novel approach to look directly into the bacterium’s behavior in the human host.”

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Global advances in synthetic biology

Drug Discovery World

The Rockefeller University 2 recently reported the development of a synthetic antibiotic that could potentially work against drug-resistant bacteria. It appears to neutralise even drug-resistant bacteria. . But with the rise of antibiotic-resistant bacteria, there is an urgent need for new active compounds.

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Anti-tumor agent from the intestine

The Pharma Data

We are talking about the microbiome – the vast collection of bacteria in the human gut. The microbiome has been the focus of research for 20 years – ever since a new technique made it possible to analyse these bacteria quickly and precisely: high-throughput sequencing. In doing so, they induce epigenetic changes.

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Stanford researchers construct the most complete synthetic microbiome

Drug Discovery World

While scientists routinely silence a gene or remove a protein from a specific cell or even an entire mouse, there is no such set of tools to remove or modify one species among the hundreds in a given faecal sample. “So They introduced hCom1 to mice that are carefully designed to have no bacteria present. Building the ark.

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Top 30 Pharma and Biotech Companies in 2023: Statistics and Trends

XTalks

Meanwhile, BioMarin’s gene therapy Roctavian is approved by the FDA for the treatment of hemophilia A. 2) Botox Therapeutic/Cosmetic Botox, or botulinum neurotoxin, is a neurotoxic protein produced by the Clostridium botulinum bacteria. But all three drugs have new competitors. Both are anti-CD20 agents. billion in 2022.

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