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A gene in tuberculosis bacteria is found essential for siderophore secretion and virulence

Scienmag

of the University of Alabama at Birmingham have made what they call “a major step” in understanding how Mycobacterium tuberculosis acquires iron from its human host — a process essential for the pathogenesis of this bacterium. . – Lei Zhang, Ph.D., and Michael Niederweis, Ph.D.,

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Researchers peer inside deadly pathogen’s burglary kit

Scienmag

Structural insights about a deadly bacterium’s toolbox point to ways to block it Credit: Maria Schumacher Lab, Duke Biochemistry DURHAM, N.C. – The bacterium that causes the tick-borne disease tularemia is a lean, mean infecting machine.

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Researchers find peptide that treats, prevents killer citrus disease

Scienmag

Treatment causes deadly bacterium to leak and die Credit: Hailing Jin/UCR New research affirms a unique peptide found in an Australian plant can destroy the No. 1 killer of citrus trees worldwide and help prevent infection. Huanglongbing, HLB, or citrus greening has multiple names, but one ultimate result: bitter and worthless citrus fruits.

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Swiss scientists identify a virus that kills dormant bacteria

Drug Discovery World

How phages work still a mystery In 2019, the team isolated a new, previously unknown virus that infects Pseudomonas aeruginosa, a bacterium that can cause serious respiratory diseases like pneumonia. However, you need to know exactly how a phage attacks a bacterium before you can select the right phages for a particular treatment.

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Symvivo’s Oral COVID-19 Vaccine Enters Clinical Trials

XTalks

The Burnaby, BC-based company developed the oral DNA-based vaccine using its proprietary bacTRL Gene Therapy Platform, which uses genetically modified bifidobacteria as carriers of genetic vaccine elements on a DNA plasmid. BacTRL Gene Therapy Platform. Related: Red Meat Allergy Test Gets FDA Clearance. “We

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Scientists discover small RNA that regulates bacterial infection

The Pharma Data

Pseudomonas aeruginosa, a common environmental bacterium, can colonize different body parts, such as the lungs, leading to persistent, chronic infections that can last a lifetime – a common occurrence in people with cystic fibrosis. “And at this point, the function of the gene was unknown.” and Nelson D.

RNA 40
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Global advances in synthetic biology

Drug Discovery World

The Brady lab has been finding antibacterial genes in soil and growing them within more lab-friendly bacteria. Most antibiotics are derived from genetic sequences locked within so-called biosynthetic gene clusters, which are genes that function as a unit to collectively code for a series of proteins.